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The role of the piriform cortex in temporal lobe epilepsy: A current literature review [PDF]

open access: yesFrontiers in Neurology, 2022
Temporal lobe epilepsy is the most common form of focal epilepsy and can have various detrimental consequences within many neurologic domains. Recent evidence suggests that the piriform cortex may also be implicated in seizure physiology.
Keanu Chee   +6 more
doaj   +3 more sources

Occurrence of new neurons in the piriform cortex [PDF]

open access: yesFrontiers in Neuroanatomy, 2015
Adult neurogenesis has been well studied in hippocampus and subventricular zone; while this is much less appreciated in other brain regions, including amygdala, hypothalamus and piriform cortex.
Ti-Fei eYuan   +2 more
doaj   +9 more sources

Mixture Coding and Segmentation in the Anterior Piriform Cortex [PDF]

open access: yesFrontiers in Systems Neuroscience, 2020
Coding of odorous stimuli has been mostly studied using single isolated stimuli. However, a single sniff of air in a natural environment is likely to introduce airborne chemicals emitted by multiple objects into the nose.
Sapir Penker   +3 more
doaj   +4 more sources

Elevated tau in the piriform cortex in Alzheimer's but not Parkinson's disease using PET‐MR [PDF]

open access: yesAlzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION Olfactory dysfunction can be an early sign of Alzheimer's disease (AD). We used tau positron emission tomography‐magnetic resonance (PET‐MR) to analyze a key region of the olfactory circuit, the piriform cortex, in comparison to the adjacent
Hossein Moein Taghavi   +18 more
doaj   +2 more sources

Interictal blood–brain barrier dysfunction in piriform cortex of people with epilepsy [PDF]

open access: yesAnnals of Clinical and Translational Neurology
Objective The piriform cortex is considered to be highly epileptogenic. Its resection during epilepsy surgery is a predictor for postoperative seizure freedom in temporal lobe epilepsy. Epilepsy is associated with a dysfunction of the blood–brain barrier.
Freya Schulte   +20 more
doaj   +2 more sources

LRP4 is required for the olfactory association task in the piriform cortex [PDF]

open access: yesCell & Bioscience, 2022
Background Low-density lipoprotein receptor-related protein 4 (LRP4) plays a critical role in the central nervous system (CNS), including hippocampal synaptic plasticity, maintenance of excitatory synaptic transmission, fear regulation, as well as long ...
Min Yan   +12 more
doaj   +2 more sources

Intracranial investigation of piriform cortex epilepsy during odor presentation. [PDF]

open access: yesNeurocase, 2023
Abstract The piriform cortex is part of the olfactory system, principally receiving input from the lateral olfactory tract and projecting to downstream components of the olfactory network, including the amygdala. Based on preclinical studies, the piriform cortex is vulnerable to injury and can be easily kindled as an onset site for seizures ...
Bearden DJ   +10 more
europepmc   +5 more sources

Lineage Relationships Between Subpallial Progenitors and Glial Cells in the Piriform Cortex [PDF]

open access: yesFrontiers in Neuroscience, 2022
The piriform cortex is a paleocortical area, located in the ventrolateral surface of the rodent forebrain, receiving direct input from the olfactory bulb.
Rebeca Sánchez-González   +1 more
doaj   +2 more sources

The Piriform Cortex and Human Focal Epilepsy [PDF]

open access: yesFrontiers in Neurology, 2014
It is surprising that the piriform cortex, when compared to the hippocampus, has been given relatively little significance in human epilepsy. Like the hippocampus, it has a phylogenetically preserved three-layered cortex that is vulnerable to excitotoxic
David eVaughan   +4 more
doaj   +4 more sources

Lateral entorhinal cortex afferents reconfigure the activity in piriform cortex circuits. [PDF]

open access: yesProc Natl Acad Sci U S A
AbstractOdours are key signals for guiding spatial behaviours such as foraging and navigation in rodents. It has recently been found that odour representations in the piriform cortex (PCx) can also contain information about their spatial context. However, the precise origins of this information within the brain and its subsequent integration into the ...
Pedroncini O   +2 more
europepmc   +5 more sources

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