Results 91 to 100 of about 20,909 (254)

Molecular signatures of neural connectivity in the olfactory cortex

Nature Communications, 2016
The piriform cortex projects to multiple brain regions involved in diverse aspects of olfactory behavior but information about the organization of these outputs is lacking.
Assunta Diodato, Marion Ruinart de Brimont, Yeong Shin Yim, Nicolas Derian, Sandrine Perrin, Juliette Pouch, David Klatzmann, Sonia Garel, Gloria B Choi, Alexander Fleischmann   +9 more
doaj   +1 more source

Distinct medial temporal volumetric signatures in extra‐medial temporal lobe lesional epilepsy

Epilepsia Open, EarlyView.
Abstract Objective To quantify amygdala and hippocampal volumetric asymmetries in patients with drug‐resistant epilepsy (DRE) and extra‐medial temporal lesions (EMTLs) and to assess the prevalence of structural alterations relative to drug‐resistant temporal lobe epilepsy (TLE), extratemporal lobe epilepsy (ETLE), and healthy individuals.
Yonatan Serlin, Bijal Patel, Elena Hayday, Alexandrea Kilgore‐Gomez, Tianxia Wu, Shareena A. Rahman, William H. Theodore, Sara K. Inati   +7 more
wiley   +1 more source

Modulation of Inhibitory Synaptic Potentials in the Piriform Cortex [PDF]

Journal of Neurophysiology, 1999
Modulation of inhibitory synaptic potentials in the piriform cortex. Intracellular recordings from pyramidal neurons in brain slice preparations of the piriform cortex were used to test results from a computational model about the effects of cholinergic agonists on inhibitory synaptic potentials induced by stimulation of afferent fibers in layer Ia ...
M M, Patil, M E, Hasselmo
openaire   +2 more sources

Spatial and temporal evolution of neuronal activation, stress and injury in lithium-pilocarpine seizures in adult rats. [PDF]

, 1998
In order to follow the spatial and temporal evolution of neuronal damage, cellular activation and stress responses subsequent to lithium-pilocarpine seizures of various durations in the adult rat, we analyzed the expression of Fos protein and local ...
Baram, TZ, Fernandes, MJ, Motte, J, Nehlig, A   +3 more
core   +2 more sources

Is Dysphagia in Multiple System Atrophy Responsive to Levodopa? Results from a Retrospective Study

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Dysphagia remains a major clinical concern in multiple system atrophy (MSA), and so far, lacks relevant treatment options. Objective To systematically assess levodopa‐responsiveness of dysphagia in MSA. Methods 19 MSA‐patients underwent endoscopic swallowing evaluation in Off‐ and On‐state, following an adapted FEES‐levodopa‐test ...
Florin Gandor, Luise Berger, Vera Jäger, Katharina Demmin, Doreen Gruber, Katja Schimming, Paulina Thimm, Georg Ebersbach, Stefanie Schreiber, Dominic Rowe, Annemarie Vogel   +10 more
wiley   +1 more source

Orchestration of Hippocampal Information Encoding by the Piriform Cortex [PDF]

Cerebral Cortex, 2019
Abstract The hippocampus utilizes olfactospatial information to encode sensory experience by means of synaptic plasticity. Odor exposure is also a potent impetus for hippocampus-dependent memory retrieval. Here, we explored to what extent the piriform cortex directly impacts upon hippocampal information processing and storage.
Strauch, Christina, Manahan-Vaughan, Denise   +1 more
openaire   +2 more sources

Perampanel Blocks Transsynaptic α‐Synuclein Propagation and Neurodegeneration in a Mouse Model of Lewy Body Disease

Movement Disorders, EarlyView.
Abstract Background Transsynaptic α‐synuclein propagation plays a crucial role in the progression of Lewy body disease. We previously demonstrated that an α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor antagonist, perampanel, blocks neuronal uptake of α‐synuclein preformed fibrils (PFFs) in an activity‐dependent manner.
Jun Ueda, Norihito Uemura, Jiarui Chang, Tetsuya Hirato, Tomoyuki Ishimoto, Miki Oono, Shuichi Matsuzawa, Riki Matsumoto, Hodaka Yamakado, Ryosuke Takahashi   +9 more
wiley   +1 more source

Layer-specific expression of extracellular matrix molecules in the mouse somatosensory and piriform cortices

IBRO Reports, 2019
In the developing central nervous system (CNS), extracellular matrix (ECM) molecules have regulating roles such as in brain development, neural-circuit maturation, and synaptic-function control.
Hiroshi Ueno, Shunsuke Suemitsu, Shinji Murakami, Naoya Kitamura, Kenta Wani, Yosuke Matsumoto, Motoi Okamoto, Takeshi Ishihara   +7 more
doaj   +1 more source

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

Journal of Internal Medicine, EarlyView.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

Prenatal genesis of layer II doublecortin expressing neurons in neonatal and young adult guinea pig cerebral cortex

Frontiers in Neuroanatomy, 2015
Cells expressing doublecortin (DCX+) occur at cortical layer II, predominantly over the paleocortex in mice/rats, but also across the neocortex among larger mammals.
Yan eYang, Mi-Xin eXie, Jian-Ming eLi, Xia eHu, Peter ePatrylo, Xue-Gang eLuo, Yan eCai, ZHIYUAN eLI, Xiao-Xin eYan   +8 more
doaj   +1 more source