Results 51 to 60 of about 496,447 (247)

Network Dynamics in the Developing Piriform Cortex of Unanesthetized Rats.

Cerebral Cortex, 2020
The time course of changes in functional cortical activity during early development has been extensively studied in the rodent visual system. A key period in this process is the time of eye opening, which marks the onset of patterned visual input and ...
Zihao Zhang, Donald Chad Collins, Joost X. Maier   +2 more
semanticscholar   +1 more source

TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy [PDF]

, 2017
Significance Alzheimer’s disease (AD) is the most common cause of dementia and is a major public health problem for which there is currently no disease-modifying treatment.
Anderson, Elise, Colonna, Marco, Finn, Mary B., Holtzmann, David M., Koscal, Lauren J., Leyns, Cheryl E. G., Robinson, Grace O., Serrano, Javier Remolina, Stewart, Floy R., Ulrich, Jason D.   +9 more
core   +2 more sources

Odor identity coding by distributed ensembles of neurons in the mouse olfactory cortex

eLife, 2017
Olfactory perception and behaviors critically depend on the ability to identify an odor across a wide range of concentrations. Here, we use calcium imaging to determine how odor identity is encoded in olfactory cortex.
Benjamin Roland, Thomas Deneux, Kevin M Franks, Brice Bathellier, Alexander Fleischmann   +4 more
doaj   +1 more source

Individual odor hedonic perception is coded in temporal joint network activity

NeuroImage, 2021
Intro: The human sense of smell is highly individual and characterized by a strong variability in the perception and evaluation of olfactory stimuli, depending on cultural imprint and current physiological conditions.
Paul Ruser, Carina J. Koeppel, Hagen H. Kitzler, Thomas Hummel, Ilona Croy   +4 more
doaj   +1 more source

Synaptophysin and synaptoporin expression in the developing rat olfactory system [PDF]

, 1993
The expressions of two closely related synaptic vesicle antigens synaptophysin and synaptoporin were examined in the olfactory system of the adult rat and during pre- and postnatal development.
Bayer, Bergmann, Betz, Bixby, Breipohl, Brunjes, Elferink, Farbman, Farbman, Fletcher, Geppert, Gesteland, Graziadei, Halász, Halász, Hinds, Hsu, Huttner, Jahn, Jahn, Knaus, Kosaka, Lahr, Lahr, Leube, Mandell, Marchand, Margolis, Marquèze-Pouey, Matteoli, McLean, Navone, Ovtscharoff, Pedersen, Rehn, Schwob, Schwob, Shipley, Smotherman, Specht, Specht, Südhof, Thomas, Thomas, Tixier-Vidal, Trimble, Van Lookeren Campagne, Verhaagen, Wendland, Wiedenmann, Zhong   +50 more
core   +1 more source

Expression time course and spatial distribution of activated caspase-3 after experimental status epilepticus: Contribution of delayed neuronal cell death to seizure-induced neuronal injury

Neurobiology of Disease, 2005
Pilocarpine-induced status epilepticus (PCSE) is a widely used model to study neurodegeneration in limbic structures after prolonged epileptic seizures.
Jens Weise, Tobias Engelhorn, Arnd Dörfler, Stefanie Aker, Mathias Bähr, Andreas Hufnagel   +5 more
doaj   +1 more source

NF-κB "decoy" inhibits COX-2 expression in epileptic rat brain [PDF]

Journal of Integrative Neuroscience, 2020
There is a need to investigate the role of nuclear factor kappa B in the regulation of cyclooxygenase-2 expression in the epileptic rat brain and cultured hippocampal neurons.
Jing Xu, Yiping Sun, Yongshun Zhao, Qifa Li, Biying Ge, Shufang Dai, Kemin Liu, Hong Xu, Lei Fu, Jie Zhao
doaj   +1 more source

Association of Piriform Cortex Resection With Surgical Outcomes in Patients With Temporal Lobe Epilepsy.

JAMA Neurology, 2019
Importance A functional area associated with the piriform cortex, termed area tempestas, has been implicated in animal studies as having a crucial role in modulating seizures, but similar evidence is limited in humans.
M. Galovic, I. Baudracco, Evan Wright-Goff, Galo Pillajo, P. Nachev, B. Wandschneider, F. Woermann, P. Thompson, S. Baxendale, A. McEvoy, M. Nowell, M. Mancini, S. Vos, G. Winston, R. Sparks, F. Prados, A. Miserocchi, Jane de Tisi, Louis A van Graan, R. Rodionov, Chengyuan Wu, M. Alizadeh, Lauren Kozlowski, A. Sharan, Lohith G. Kini, K. Davis, B. Litt, S. Ourselin, S. Moshé, Josemir W Sander, W. Löscher, J. Duncan, M. Koepp   +32 more
semanticscholar   +1 more source

Early Gabapentin Treatment during the Latency Period Increases Convulsive Threshold, Reduces Microglial Activation and Macrophage Infiltration in the Lithium-Pilocarpine Model of Epilepsy [PDF]

, 2017
The lithium-pilocarpine model of epilepsy reproduces several features of temporal lobe epilepsy in humans, including the chronological timeline of an initial latency period followed by the development of spontaneous seizures. Epilepsy therapies in humans
Auzmendi, Jerónimo Andrés, Murta, Verónica, Ramos, Alberto, Rossi, Alicia Raquel   +3 more
core   +3 more sources

The functional upregulation of piriform cortex is associated with cross-modal plasticity in loss of whisker tactile inputs.

PLoS ONE, 2012
BackgroundCross-modal plasticity is characterized as the hypersensitivity of remaining modalities after a sensory function is lost in rodents, which ensures their awareness to environmental changes.
Bing Ye, Li Huang, Zilong Gao, Ping Chen, Hong Ni, Sudong Guan, Yan Zhu, Jin-Hui Wang   +7 more
doaj   +1 more source