Odor identity coding by distributed ensembles of neurons in the mouse olfactory cortex
eLife, 2017 Olfactory perception and behaviors critically depend on the ability to identify an odor across a wide range of concentrations. Here, we use calcium imaging to determine how odor identity is encoded in olfactory cortex.
Benjamin Roland +4 more
doaj +1 more source
Individual odor hedonic perception is coded in temporal joint network activity
NeuroImage, 2021 Intro: The human sense of smell is highly individual and characterized by a strong variability in the perception and evaluation of olfactory stimuli, depending on cultural imprint and current physiological conditions.
Paul Ruser +4 more
doaj +1 more source
TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy [PDF]
, 2017 Significance Alzheimer’s disease (AD) is the most common cause of dementia and is a major public health problem for which there is currently no disease-modifying treatment.
Anderson, Elise +9 more
core +2 more sources
Effect of delayed acquisition times on Gadolinium-enhanced MRI of the presumably normal canine brain [PDF]
, 2011 A delay in imaging following intravenous contrast medium administration has been recommended to reduce misdiagnoses. However, the normal variation of contrast enhancement in dogs following a delay has not been characterized.
Brannan, N. +5 more
core +1 more source
Neurobiology of Disease, 2005 Pilocarpine-induced status epilepticus (PCSE) is a widely used model to study neurodegeneration in limbic structures after prolonged epileptic seizures.
Jens Weise +5 more
doaj +1 more source
NF-κB "decoy" inhibits COX-2 expression in epileptic rat brain [PDF]
Journal of Integrative Neuroscience, 2020 There is a need to investigate the role of nuclear factor kappa B in the regulation of cyclooxygenase-2 expression in the epileptic rat brain and cultured hippocampal neurons.
Jing Xu, Yiping Sun, Yongshun Zhao, Qifa Li, Biying Ge, Shufang Dai, Kemin Liu, Hong Xu, Lei Fu, Jie Zhao
doaj +1 more source
Early Gabapentin Treatment during the Latency Period Increases Convulsive Threshold, Reduces Microglial Activation and Macrophage Infiltration in the Lithium-Pilocarpine Model of Epilepsy [PDF]
, 2017 The lithium-pilocarpine model of epilepsy reproduces several features of temporal lobe epilepsy in humans, including the chronological timeline of an initial latency period followed by the development of spontaneous seizures. Epilepsy therapies in humans
Auzmendi, Jerónimo Andrés +3 more
core +3 more sources
Odor-intensity Coding in the Anterior Piriform Cortex [PDF]
Chemical Senses, 2005 The primary olfactory cortex is defined as the region that receivesdirect fiber projection from the olfactory bulb (OB). The piriformcortex (PC) is the largest structure in the olfactory cortex. However,no ‘point to point’ anatomical connection between the OB and PChas been found (Haberly, 1998).
Norihiko, Onoda +2 more
openaire +2 more sources
eLife, 2020 Pattern completion, or the ability to retrieve stable neural activity patterns from noisy or partial cues, is a fundamental feature of memory. Theoretical studies indicate that recurrently connected auto-associative or discrete attractor networks can ...
Kevin A Bolding +4 more
doaj +1 more source
Olfactory cortical neurons read out a relative time code in the olfactory bulb [PDF]
, 2014 Odor stimulation evokes complex spatiotemporal activity in the olfactory bulb, suggesting that the identity of activated neurons as well as the timing of their activity convey information about odors.
Haddad, Rafi +5 more
core +1 more source