Cytoprotective and enhanced anti-inflammatory activities of liposomal piroxicam formulation in lipopolysaccharide-stimulated RAW 264.7 macrophages [PDF]
Hoe Siong Chiong,1 Yoke Keong Yong,1 Zuraini Ahmad,1 Mohd Roslan Sulaiman,1 Zainul Amiruddin Zakaria,1 Kah Hay Yuen,2 Muhammad Nazrul Hakim1,31Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia; 2School of ...
Chiong HS +6 more
doaj +3 more sources
Development and Validation of an in-line API Quantification Method Using AQbD Principles Based on UV-Vis Spectroscopy to Monitor and Optimise Continuous Hot Melt Extrusion Process [PDF]
A key principle of developing a new medicine is that quality should be built in, with a thorough understanding of the product and the manufacturing process supported by appropriate process controls. Quality by design principles that have been established
Juan Almeida +5 more
doaj +4 more sources
The protective effects of garlic (Allium sativum var. Solo Garlic) extract mitigates piroxicam-induced liver damage and oxidative stress in rats [PDF]
Background: Piroxicam, a nonsteroidal antiinflammatory drug, is commonly used to induce inflammation in experimental models of inflammatory bowel disease (IBD).
Maya Nurwartanti Yunita +10 more
doaj +2 more sources
Self-nanoemulsifying drug delivery system (SNEDDS) of piroxicam: evaluation on anti-inflammantory activity in wistar rats [PDF]
Piroxicam is a non-steroidal anti-inflammatory drug (NSAID) that is commonly used for arthritis, gout, and other musculoskeletal disorders. Piroxicam is poorly soluble in water and according to the biopharmaceutical drug classification system (BCS) is ...
Yudha Rizky Nuari +2 more
doaj +1 more source
Purpose: In this study, a controlled release drug delivery system loaded with piroxicam and methadone was synthesized and used subcutaneously in rat with experimental tibial defect and healing were assessed histopathologically. Materials and Methods:
Pegah Khosravian +5 more
doaj +1 more source
Photostability of piroxicam in the inclusion complex with 2-hydroxypropyl-β-cyclodextrin [PDF]
The aim of this work is the protection of piroxicam from photodegradation by forming inclusion complex with 2-hydroxypropyl-β-cyclodextrin. Piroxicam:2-hydroxypropyl-β-cyclodextrin molecular inclusion complex was prepared by coprecipitation ...
Nikolić Vesna D. +6 more
doaj +1 more source
Piroxicam belongs to BCS class II and has low solubility. Self-nanoemulsifying drug delivery systems (SNEDDS) are considered a potential approach for increasing the solubility and release of piroxicam.
Septiawan Adi Nugroho +2 more
doaj +1 more source
Reducing ulcerogenic effect of self-nano emulsifying drug delivery system of piroxicam [PDF]
Piroxicam is antiinflammatory non-steroidal (AINS) drug group that has anti-inflammatory, analgesic and antipyretic effects. Like most other AINS drugs, piroxicam has low solubility and has gastrointestinal (ulcerogenic) side effects on long-term use ...
Iis Wahyuningsih +2 more
doaj +1 more source
Background: Piroxicam is one of the nonsteroidal anti-inflammatory drugs used as antipyretic, analgesic and anti-inflammatory drug often used for the relief of nonspecific fever condition and in arthritis. This study investigated the protective potential
Tijani Stephanie Abiola +2 more
doaj +1 more source

