Results 11 to 20 of about 17,854 (186)

Pharmaceutical Cocrystal of Piroxicam: Design, Formulation and Evaluation [PDF]

Advanced Pharmaceutical Bulletin, 2017
Purpose: Cocrystallisation of drug with coformers is a promising approach to alter the solid sate properties of drug substances like solubility and dissolution.
Prabhakar Panzade, Giridhar Shendarkar, Sarfaraj Shaikh, Pavan Balmukund Rathi   +3 more
doaj   +1 more source

Nonsteroidal Anti-Inflammatory Drugs and Risk of Gastrointestinal Bleeding: A Systematic Review and Meta-Analysis. [PDF]

Clin Pharmacol Ther
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used for pain and inflammation but are associated with gastrointestinal (GI) bleeding. While this risk is well established, most studies evaluate NSAIDs as a homogenous class, limiting clinical decision‐making based on individual agent safety.
Tawfik AG, Gomez-Lumbreras A, Del Fiol G, Kawamoto K, Trinkley KE, Reese T, Jones A, Malone DC.   +7 more
europepmc   +2 more sources

Electrocatalytic performance of Au@Cu Nanoparticle Chains as Sensor for Determination of Piroxicam

International Journal of Electrochemical Science, 2021
A chemical reduction technique at low temperature was employed to synthesize Au and Cu nanoparticle chains (Au@Cu NCs) with sodium citrate as the growth reducing agent, stabilizer and structure directing agent, chloroauric acid (HAuCl4) and copper ...
Na Wu, Guanmei Yang, Jinming Meng, Guiyang Liu, Shaoping Feng, Xianlan Chen, Guowei Zhang   +6 more
doaj   +1 more source

Pengaruh Pemberian Ekstrak Jintan Hitam (Nigella sativa) terhadap Kadar MDA dan SOD Hepar Tikus (Rattus norvegicus) yang Diinduksi Piroxicam

Jurnal Fisika Flux, 2021
Piroxicam merupakan salah satu obat anti inflamasi non steroid (OAINS) yang berpotensi menyebabkan kerusakan sel pada organ hepar. Kerusakan hepar ditandai dengan tingginya kadar MDA (Malondialdehyde) dalam darah.
Septiana Kurniasari
doaj   +1 more source

Apoptosis induced by piroxicam plus cisplatin combined treatment is triggered by p21 in mesothelioma. [PDF]

PLoS ONE, 2011
BackgroundMalignant mesothelioma (MM) is a rare, highly aggressive tumor, associated to asbestos exposure. To date no chemotherapy regimen for MM has proven to be definitively curative, and new therapies for MM treatment need to be developed.
Alfonso Baldi, Maria Teresa Piccolo, Maria Rosaria Boccellino, Aldo Donizetti, Irene Cardillo, Raffaele La Porta, Lucio Quagliuolo, Enrico P Spugnini, Francesca Cordero, Gennaro Citro, Massimo Menegozzo, Raffaele A Calogero, Stefania Crispi   +12 more
doaj   +1 more source

Formulation and evaluation of topical piroxicam microemulgel for arthritis

Journal of Contemporary Pharmacy, 2023
Background: Piroxicam is an anti-inflammatory, analgesic, and antipyretic drug. Piroxicam is widely used in the management of chronic pain. The objective of this work was to develop and analyze topical Piroxicam microemulgel to improve drug solubility ...
Mehreen Sattar, Somia Sarfraz, Uzma Liaquat, Iqra Shoukat, Bilal Ahmad, Talib Hussain   +5 more
doaj   +1 more source

Protective potential of piroxicam on human peripheral blood mononuclear cells against the suppressive capacity of glioblastoma cell lines

Scientific Reports, 2022
Dexamethasone, a common medication used in the treatment regimen of glioblastoma, has broad inhibitory effects on the immune responses. Here, in an in vitro study, we examined the effects of piroxicam, a potent substitute for dexamethasone, on peripheral
Jahangir Abdesheikhi, Farnaz Sedghy, Alireza Farsinejad, Merat Mahmoudi, Mahdi ranjkesh, Meysam Ahmadi-Zeidabadi   +5 more
doaj   +1 more source

Comparison of Analgesic Effect of Rosmarinic Acid With Piroxicam in Mice [PDF]

International Journal of Basic Science in Medicine, 2022
Introduction: Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the most widely used drugs in the treatment of pain and inflammation. Although, their side effects i.e.; gastrointestinal and renal adverse effects, limit the use of these drugs ...
Mohsen Moradi, Mahdi Mashhadi Akbar Boojar, Mehdi Saberi, Hamidreza Rahimi Salkuyeh, Maryam Ghorbani, Hasan Amanpour, Fateme Salem   +6 more
doaj   +1 more source

Protective effect of antioxidant rich aqueous curry leaf (Murraya koenigii) extract against gastro-toxic effects of piroxicam in male Wistar rats

Toxicology Reports, 2014
Piroxicam (chemically 4-hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide), a classical non-steroidal anti-inflammatory drug (NSAID) is orally administered to arthritic patients.
Syed Benazir Firdaus, Debosree Ghosh, Aindrila Chattyopadhyay, Mousumi Dutta, Sudeshna Paul, Jagannath Jana, Anjali Basu, Gargi Bose, Hiya Lahiri, Bhaswati Banerjee, Sanjib Pattari, Subhrangshu Chatterjee, Kuladip Jana, Debasish Bandyopadhyay   +13 more
doaj   +1 more source

Meloxicam decreases the migration and invasion of CF41.Mg canine mammary carcinoma cells [PDF]

, 2017
Indexación: Web of Science; Scopus.Cyclooxygenase (COX)-2 expression is positively correlated with malignant features in canine mammary carcinomas. Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit COX activity and may therefore possess anticancer ...
Arias, J.I., Iturriaga, M.P., Paredes, R., Torres, C.G.   +3 more
core   +1 more source