Results 11 to 20 of about 165,839 (215)

Glycometabolic Alterations in Secondary Adrenal Insufficiency: Does Replacement Therapy Play a Role? [PDF]

open access: yes, 2018
Secondary adrenal insufficiency (SAI) is a potentially life-threatening endocrine disorder due to an impairment of corticotropin (ACTH) secretion from any process affecting the hypothalamus or pituitary gland.
Gianfrilli, Daniele   +5 more
core   +6 more sources

Sexual Differentiation of Circadian Clock Function in the Adrenal Gland [PDF]

open access: yes, 2016
Sex differences in glucocorticoid production are associated with increased responsiveness of the adrenal gland in females. However, the adrenal-intrinsic mechanisms that establish sexual dimorphic function remain ill defined. Glucocorticoid production is
Evans, Jennifer A.   +5 more
core   +2 more sources

Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue. [PDF]

open access: yes, 1981
Two different monoclonal antibodies, characterized initially as binding synaptic terminal regions of rat brain, bind a 65,000-dalton protein, which is exposed on the outer surface of brain synaptic vesicles. Immunocytochemical experiments at the electron
Matthew, WD, Reichardt, LF, Tsavaler, L
core   +2 more sources

Perioperative Changes in the Pituitary-Adrenal and Pituitary-Thyroid Systems and Their Correction in Females with Severe Gestosis

open access: yesОбщая реаниматология, 2006
Objective: to study the venous blood levels of adrenocorticotropic hormone (ACTH), cortisol, thyrotropic hormone, and thyroxin in females with severe gestosis in the perioperative period and to develop a method for correction of the hormonal status ...
V. M. Zhenilo, I. V. Mikhno
doaj   +1 more source

Effects of loperamide on the human hypothalamo-pituitary-adrenal axis in vivo and in vitro. [PDF]

open access: yes, 1992
Loperamide, an opiate agonist of high specificity for p-receptors, was recently reported to suppress ACTH and cortisol levels in normal subjects, but not in patients with proven ACTH-dependent Cushing’s disease. However, there is little information on
Auernhammer, Christoph J.   +4 more
core   +1 more source

Effect of date seed (Phoenix dactylifera) supplementation as functional food on cardiometabolic risk factors, metabolic endotoxaemia and mental health in patients with type 2 diabetes mellitus: a blinded randomised controlled trial protocol

open access: yesBMJ Open, 2023
Introduction Recently, the improvement of chronic hyperglycaemia-related damage of type 2 diabetes mellitus (T2DM) through functional food consumption has attracted the attention of many clinicians.
Mehdi Mohammadi Zadeh   +2 more
doaj   +1 more source

Trilostane in dogs [PDF]

open access: yes, 2010
Over the last 10 years, trilostane, a competitive inhibitor of steroid synthesis, is being widely used for the treatment of canine hyperadrenocorticism.
Alenza   +59 more
core   +1 more source

Inflammatory Signaling in Hypertension: Regulation of Adrenal Catecholamine Biosynthesis

open access: yesFrontiers in Endocrinology, 2018
The immune system is increasingly recognized for its role in the genesis and progression of hypertension. The adrenal gland is a major site that coordinates the stress response via the hypothalamic-pituitary-adrenal axis and the sympathetic-adrenal ...
Collin J. Byrne   +7 more
doaj   +1 more source

Ipilimumab, not just another anti-cancer therapy: hypophysitis as side effect illustrated by four case-reports [PDF]

open access: yes, 2014
Ipilimumab is a monoclonal antibody that blocks cytotoxic T-lymphocyte antigen4 (CTLA-4), an inhibitory molecule typically expressed on T cells. Blockade of CTLA-4 induces an overall activation of T cells, including an immune-mediated anti-tumour ...
Brochez, Lieve   +4 more
core   +2 more sources

A review of the endocrine disrupting effects of micro and nano plastic and their associated chemicals in mammals

open access: yesFrontiers in Endocrinology, 2023
Over the years, the vaste expansion of plastic manufacturing has dramatically increased the environmental impact of microplastics [MPs] and nanoplastics [NPs], making them a threat to marine and terrestrial biota because they contain endocrine disrupting
Sana Ullah   +6 more
doaj   +1 more source

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