Results 21 to 30 of about 112,170 (313)

Inflammatory Signaling in Hypertension: Regulation of Adrenal Catecholamine Biosynthesis

Frontiers in Endocrinology, 2018
The immune system is increasingly recognized for its role in the genesis and progression of hypertension. The adrenal gland is a major site that coordinates the stress response via the hypothalamic-pituitary-adrenal axis and the sympathetic-adrenal ...
Collin J. Byrne, Sandhya Khurana, Aseem Kumar, Aseem Kumar, T. C. Tai, T. C. Tai, T. C. Tai, T. C. Tai   +7 more
doaj   +1 more source

A Recessive Mutation Resulting in a Disabling Amino Acid Substitution (T194R) in the LHX3 Homeodomain Causes Combined Pituitary Hormone Deficiency [PDF]

, 2012
Background/Aims: Recessive mutations in the LHX3 homeodomain transcription factor gene are associated with developmental disorders affecting the pituitary and nervous system. We describe pediatric patients with combined pituitary hormone deficiency (CPHD)
Hiedl, Stefan, Duran-Prado, Mario, Lohse, Peter, Roeb, Julia, Rhodes, Simon J., Malik, Raleigh E., Bechtold-Dalla Pozza, Susanne, Park, Soyoung   +7 more
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A review of the endocrine disrupting effects of micro and nano plastic and their associated chemicals in mammals

Frontiers in Endocrinology, 2023
Over the years, the vaste expansion of plastic manufacturing has dramatically increased the environmental impact of microplastics [MPs] and nanoplastics [NPs], making them a threat to marine and terrestrial biota because they contain endocrine disrupting
Sana Ullah, Shahid Ahmad, Xinle Guo, Saleem Ullah, Sana Ullah, Ghulam Nabi, Kunyuan Wanghe   +6 more
doaj   +1 more source

Impairment of adrenocortical function associated with increased plasma tumor necrosis factor-alpha and interleukin 6 concentrations in African trypanosomiasis [PDF]

, 1994
African sleeping sickness (SS) is a severe, potentially lethal parasitic disease. The treatments of choice are the antiparasitic agents suramin, which is adrenotoxic, and/or melarsoprol. We evaluated the functional integrity of the hypothalamic-pituitary-
Winkelmann, W., Reincke, M, Allolio, B., Siekmann, L., Heppner, C, Arlt, W, Petzke, F, Arlt, W., Mbulamberi, D, Vollmer, D, Chrousos, G. P., Allolio, B, Siekmann, L, Vollmer, D., Heppner, C., Mbulamberi, D., Winkelmann, W, Reincke, Martin, Petzke, F., Chrousos, G P   +19 more
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Transcriptional Analysis of Sepsis-Induced Activation and Damage of the Adrenal Endothelial Microvascular Cells

Frontiers in Endocrinology, 2020
Bacterial sepsis is a serious threat to the body homeostasis and is often associated with high mortality in non-coronary intensive stations.
Lan-Sun Chen, Lan-Sun Chen, Sumeet P. Singh, Gregor Müller, Stefan R. Bornstein, Waldemar Kanczkowski   +5 more
doaj   +1 more source

Corticotropin-Releasing Hormone: A Novel Stimulator of Somatolactin in Teleost Pituitary Cells

Cells, 2023
Corticotropin-releasing hormone (CRH) is known for its crucial role in the stress response system, which could induce pituitary adrenocorticotropic hormone (ACTH) secretion to promote glucocorticoid release in the adrenal gland.
Ruixin Du, Xuetao Shi, Feng Chen, Li Wang, Hongwei Liang, Guangfu Hu   +5 more
doaj   +1 more source

The origin of glucocorticoid hormone oscillations.

PLoS Biology, 2012
Oscillating levels of adrenal glucocorticoid hormones are essential for optimal gene expression, and for maintaining physiological and behavioural responsiveness to stress.
Jamie J Walker, Francesca Spiga, Eleanor Waite, Zidong Zhao, Yvonne Kershaw, John R Terry, Stafford L Lightman   +6 more
doaj   +1 more source

Progressive onset of adrenal insufficiency and hypogonadism of pituitary origin caused by a complex genetic rearrangement within DAX-1

, 2002
DAX-1 [dosage-sensitive sex reversal, adrenal hypoplasia congenital (AHC) critical region on the X chromosome, gene 11 is a transcription factor expressed in the adrenal gland and at all levels of the gonadotrope axis.
Gaillard, R.C., Schorderet, D., Schorderet, D, Jameson, J.L., Pralong, F.P., Gaillard, RC, Fiaux, M., Achermann, JC, Salvi, R, Achermann, J.C., Gomez, F, Fiaux, M, Pralong, FP, Jameson, JL, Salvi, R., Gomez, F.   +15 more
core   +1 more source

Temporal and spatial dynamics of corticosteroid receptor down-regulation in rat brain following social defeat [PDF]

, 2001
The experiments explored the nature and time course of changes in glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) binding in homogenates of various brain regions and pituitary of male Wistar rats following social defeat stress.
Horváth, K.M., Bohus, B., Bohus, B, Bauke Buwalda, Nyakas, C, Felszeghy, K., Felszeghy, K, Béla Bohus, Klára Felszeghy, Horváth, Katalin M.,, Koolhaas, J M, Buwalda, B, Boer, Sietse F. de,, Nyakas, Csaba,, Csaba Nyakas, Katalin M Horváth, de Boer, S.F., Felszeghy, Klára,, Koolhaas, J.M., Sietse F de Boer, Koolhaas, Jaap M.,, Nyakas, C., Buwalda, Bauke,, Horváth, K M, Buwalda, B., Bohus, Béla,, Jaap M Koolhaas   +26 more
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Glucocorticoid receptor signaling in the brain and its involvement in cognitive function

Neural Regeneration Research
The hypothalamic–pituitary–adrenal axis regulates the secretion of glucocorticoids in response to environmental challenges. In the brain, a nuclear receptor transcription factor, the glucocorticoid receptor, is an important component of the hypothalamic ...
Chonglin Su, Taiqi Huang, Meiyu Zhang, Yanyu Zhang, Yan Zeng, Xingxing Chen   +5 more
doaj   +1 more source