Results 31 to 40 of about 17,410,593 (309)

The origin of glucocorticoid hormone oscillations.

open access: yesPLoS Biology, 2012
Oscillating levels of adrenal glucocorticoid hormones are essential for optimal gene expression, and for maintaining physiological and behavioural responsiveness to stress.
Jamie J Walker   +6 more
doaj   +1 more source

Transcriptional Analysis of Sepsis-Induced Activation and Damage of the Adrenal Endothelial Microvascular Cells

open access: yesFrontiers in Endocrinology, 2020
Bacterial sepsis is a serious threat to the body homeostasis and is often associated with high mortality in non-coronary intensive stations.
Lan-Sun Chen   +5 more
doaj   +1 more source

Thyroid Disorders Change the Pattern of Response of Angiotensinase Activities in the Hypothalamus-Pituitary-Adrenal Axis of Male Rats

open access: yesFrontiers in Endocrinology, 2018
Thyroid disorders affect the hypothalamic-pituitary-adrenal axis with important consequences on the cardiovascular function in which the renin-angiotensin system plays a major role.
Ana B. Segarra   +5 more
doaj   +1 more source

The Pituitary-Adrenal Response to Paradoxical Sleep Deprivation Is Similar to a Psychological Stressor, Whereas the Hypothalamic Response Is Unique

open access: yesFrontiers in Endocrinology, 2022
Stressors of different natures induce activation of the hypothalamic-pituitary-adrenal (HPA) axis at different magnitudes. Moreover, the HPA axis response to repeated exposure is usually distinct from that elicited by a single session.
Danilo A. Moraes   +4 more
doaj   +1 more source

The actions of ethinyloestradiol on the pituitary‐adrenal system of the rat [PDF]

open access: yesBritish Journal of Pharmacology, 1970
Summary . Single doses of ethinyloestradiol stimulate the pituitary adrenal axis of the female rat during quiescent conditions. . After a stimulus which releases endogenous ACTH, there is an inhibition of the release of corticosterone from the adrenal gland, but an increase in the corticosterone stored in the gland. .
openaire   +3 more sources

Glucocorticoid receptor signaling in the brain and its involvement in cognitive function

open access: yesNeural Regeneration Research
The hypothalamic–pituitary–adrenal axis regulates the secretion of glucocorticoids in response to environmental challenges. In the brain, a nuclear receptor transcription factor, the glucocorticoid receptor, is an important component of the hypothalamic ...
Chonglin Su   +5 more
doaj   +1 more source

Morpho-functional changes of pituitary-adrenal system in the long-term course of experimental diabetes mellitus

open access: yesJournal of Education, Health and Sport, 2016
Tkachuk Yurii. Morpho-functional changes of pituitary-adrenal system in the long-term course of experimental diabetes mellitus. Journal of Education, Health and Sport. 2016;6(4):375-384. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.50532 http://
Yurii Tkachuk
doaj   +2 more sources

A Recessive Mutation Resulting in a Disabling Amino Acid Substitution (T194R) in the LHX3 Homeodomain Causes Combined Pituitary Hormone Deficiency [PDF]

open access: yes, 2012
Background/Aims: Recessive mutations in the LHX3 homeodomain transcription factor gene are associated with developmental disorders affecting the pituitary and nervous system. We describe pediatric patients with combined pituitary hormone deficiency (CPHD)
Hiedl, Stefan   +7 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

A putative role for the aryl hydrocarbon receptor (AHR) gene in a patient with cyclical Cushing’s disease

open access: yesBMC Endocrine Disorders, 2020
Background Apart from PRKAR1A mutations in a subset of cyclical Cushing’s syndrome due to primary pigmented nodular adrenocortical disease, the molecular basis of cyclical Cushing’s syndrome has not been investigated.
Sunita M. C. De Sousa   +6 more
doaj   +1 more source

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