Influence of mirtazapine on salivary cortisol in depressed patients [PDF]
, 2003 Unlike other antidepressants, mirtazapine does not inhibit the reuptake of norepinephrine or serotonin but acts as an antagonist at presynaptic alpha(2)-receptors, at postsynaptic 5-HT2 and 5-HT3 receptors, and at histaminergic H1 receptors. Furthermore,
Baghai, Thomas C. +3 more
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Frontiers in Endocrinology, 2016 Survival of all living organisms depends on maintenance of a steady state of homeostasis, which process relies on its ability to react and adapt to various physical and emotional threats.
Waldemar Kanczkowski +3 more
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Adverse effects of glucocorticoid therapy
Iatreia, 2021 Glucocorticoids are widely used medications for the management of many chronic diseases, but they are associated with multiple adverse effects that can affect different organs. In the present review, a description will be made of the effects derived from
Gutiérrez-Restrepo, Johnayro
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Chronic Heroin Dependence Leading to Adrenal Insufficiency
Case Reports in Endocrinology, 2014 Opioids have been the mainstay for pain relief and palliation over a long period of time. They are commonly abused by drug addicts and such dependence usually imparts severe physiologic effects on multiple organ systems. The negative impact of opioids on
Gautam Das
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Post-Mortem Immunohistochemical Evidence of β2-Adrenergic Receptor Expression in the Adrenal Gland [PDF]
, 2019 The evidence from post-mortem biochemical studies conducted on cortisol and catecholamines suggest that analysis of the adrenal gland could provide useful information about its role in human pathophysiology and the stress response.
Alibrandi A. +10 more
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The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders [PDF]
, 2020 Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity.
Clark, Ashley K +3 more
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Estrone and estradiol concentrations in human ovaries, testes, and adrenals during the first two years of life [PDF]
, 1987 To determine the origin of estrogens in infant blood, we measured estrone (E1) and estradiol (E2) in the gonads of 50 girls and 64 boys who died suddenly between birth and 2 yr of age as well as in the adrenals of 18 of these infant girls and 16 of the ...
Bidlingmaier, F. +4 more
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Research progress in the correlation between chronic stress and ovarian dysfunction
Shanghai Jiaotong Daxue xuebao. Yixue banThe ovary is an important reproductive organ for women. Decreased ovarian function not only affects the reproductive capabilities, but also leads to the decline of women′s quality of life.
WEI Liutong, LAI Dongmei
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Challenges in treatment of patients with non-classic congenital adrenal hyperplasia
Frontiers in Endocrinology, 2022 Congenital adrenal hyperplasia (CAH) due to 21α-hydroxylase deficiency (21OHD) or 11β-hydroxylase deficiency (11OHD) are congenital conditions with affected adrenal steroidogenesis.
Bas P. H. Adriaansen +6 more
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Leptin fails to blunt the lipopolysaccharide-induced activation of the hypothalamic-pituitary-adrenal axis in rats [PDF]
, 2014 Copyright @ 2013 The authors. This work is licensed under a Creative Commons Attribution 3.0 Unported License.Obesity is a risk factor for sepsis morbidity and mortality, whereas the hypothalamic-pituitary-adrenal (HPA) axis plays a protective role in ...
Ahima +40 more
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