Results 111 to 120 of about 770,455 (417)

Principles of Pituitary Surgery [PDF]

, 2018
Key Points 1. Understand the principles of pituitary surgery including the key-elements of surgical planning and decision-making 2. Identify the technical nuances distinguishing the endoscopic from the microscopic transsphenoidal approach 3.
Evans, James J., Farag, MD, Alexander, Farrell, MD, Christopher J, Nyquist, MD, Gurston G., Rosen, Marc, MD   +4 more
core   +2 more sources

Pituitary Adenoma Segmentation [PDF]

arXiv, 2011
Sellar tumors are approximately 10-15% among all intracranial neoplasms. The most common sellar lesion is the pituitary adenoma. Manual segmentation is a time-consuming process that can be shortened by using adequate algorithms. In this contribution, we present a segmentation method for pituitary adenoma.
arxiv  

Oxytocin‐Mediate Modulation of Splenic Immunosuppression in Chronic Social Stress Through Neuroendocrine Pathways

Advanced Science, EarlyView.
Chronic social stress elevates oxytocin levels, leading to immunosuppression by enhancing regulatory T‐cell activity and promoting anti‐inflammatory macrophage polarization in the spleen. Blocking oxytocin signaling reverses these effects but worsens stress‐induced behavioral disorders and reduces survival rates. This highlights oxytocin's dual role in
Yi‐Shu Zhang, Hai‐Chao Chen, Jia‐Xin Cao, Si‐Wei Zhou, Yue‐Zhang Ma, Yu‐Hong Jing   +5 more
wiley   +1 more source

Identifying Facial Features and Predicting Patients of Acromegaly Using Three-Dimensional Imaging Techniques and Machine Learning

Frontiers in Endocrinology, 2020
Objective: Facial changes are common among nearly all acromegalic patients. As they develop slowly, patients often fail to notice such changes before they become obvious. Consequently, diagnosis and treatment are often delayed.
Tian Meng, Xiaopeng Guo, Xiaopeng Guo, Xiaopeng Guo, Wei Lian, Wei Lian, Wei Lian, Kan Deng, Kan Deng, Kan Deng, Lu Gao, Lu Gao, Lu Gao, Zihao Wang, Zihao Wang, Zihao Wang, Jiuzuo Huang, Xiaojun Wang, Xiao Long, Bing Xing, Bing Xing, Bing Xing   +21 more
doaj   +1 more source

From pituitary adenoma to pituitary neuroendocrine tumor (PitNET): an International Pituitary Pathology Club proposal.

Endocrine-Related Cancer, 2017
The classification of neoplasms of adenohypophysial cells is misleading because of the simplistic distinction between adenoma and carcinoma, based solely on metastatic spread and the poor reproducibility and predictive value of the definition of atypical
Sylvia L. Asa, O. Casar-Borota, Philippe Chanson, Etienne Delgrange, P. Earls, S. Ezzat, Ashley B. Grossman, H. Ikeda, N. Inoshita, N. Karavitaki, M. Korbonits, E. R. Laws, Lopes Mb, N. Maartens, Ian E. McCutcheon, O. Mete, Hiroshi Nishioka, G. Raverot, Federico Roncaroli, W. Saeger, L. Syro, A. Vasiljevic, Chiara Villa, A. Wierinckx, J. Trouillas   +24 more
semanticscholar   +1 more source

Sortilin‐Mediated Rapid, Precise and Sustained Degradation of Membrane Proteins via mRNA‐Encoded Lysosome‐Targeting Chimera

Advanced Science, EarlyView.
The study identified sortilin as a promising LTR, enabling targeted degradation of oncogenic proteins through an mRNA‐encoded MedTAC strategy. In a mouse model, MedTACPTK7 reduced PTK7 by up to 80%, extended survival, and showed excellent pharmacokinetics without toxicity, providing a scalable platform for targeted therapies.
Xin Chang, Xinyu Qiu, Xiaoning Tong, Shaoju Gan, Weicheng Yi, Sitao Xie, Xiangsheng Liu, Chao Zuo, Weihong Tan   +8 more
wiley   +1 more source

Fully endoscopic far-lateral supracerebellar infratentorial approach for trigeminal neuralgia: illustrative case reports

Chinese Neurosurgical Journal
Background Trigeminal neuralgia (TN) is a common cause of craniofacial pain. The retrosigmoid approach is usually used to treat TN, but no cases of endoscopic far-lateral supracerebellar infratentorial approach (EF-SCITA) were used to undergo operation ...
Hong Yao, Wenlei Yang, Hao Tang, Yijun Cheng, Shaojian Lin, Zhe Bao Wu   +5 more
doaj   +1 more source

Sex differences in the pituitary TGFβ1 system: the role of TGFβ1 in prolactinoma development [PDF]

, 2019
Prolactinomas are the most frequent functioning pituitary adenomas, and sex differences in tumor size, behavior and incidence have been described. These differences have been associated with earlier diagnosis in woman, as well as with serum estradiol ...
Abeledo Machado, Alejandra Inés, Camilletti, María Andrea, Diaz, Graciela Susana, Faraoni, Erika Yanil, Ratner, Laura Daniela, Recouvreux, Maria Victoria, Rulli, Susana Beatriz   +6 more
core   +1 more source

A Touch Enabled Hemodynamic and Metabolic Monitor

Advanced Science, EarlyView.
This work presents a touch‐based hybrid platform for simultaneous monitoring of vital signs and sweat metabolites. With a simple tri‐finger touch of 4–6 min, users can concurrently get to know their glucose, uric acid, cortisol levels from fingertip sweat, along with blood pressure and heart rate.
Omeed Djassemi, Tamoghna Saha, Ponnusamy Nandhakumar, Muhammad Inam Khan, Hannah Fishman, Sara Earney, Chochanon Moonla, Yuchen Xu, Henry Thai, Sofia Morales‐Fermin, Gyeongho Kim, Rhea Park, Beya Acot, Oscar Wu, Cannon Wurster, An‐Yi Chang, Christopher Cheung, Julia Silberman, Shichao Ding, Joseph Wang   +19 more
wiley   +1 more source

Association of Pathology Markers with Somatostatin Analogue Responsiveness in Acromegaly

International Journal of Endocrinology, 2022
Background. Somatotroph adenomas (SAs) exhibit a variable responsiveness to somatostatin analogue (SS-a) treatment, a process that is not well understood.
George Kontogeorgos, Vyron Markussis, Eleni Thodou, Efi Kyrodimou, Theodossia Choreftaki, Panagiotis Nomikos, Kostas I. Lampropoulos, Stylianos Tsagarakis   +7 more
doaj   +1 more source