Results 131 to 140 of about 770,455 (417)
Continuous and Pulsed Experiments with Numerical Simulation to Dissect Pituitary Gland Tumour by Using Liquid Jet [PDF]
Engineering Letters, 2017, 2019 Endoscopic endonasal surgery is a minimal invasive surgery that has been used to dissect pituitary gland tumour via curettes with the help of endoscope. However, this type of surgery has a high risk of failure because curettes may cause damages to blood vessels and optical nerves that lead to more complication for the patient.
arxiv
Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours
Nature Communications, 2018 Aberrant expression of long noncoding RNA H19 has been associated with tumour progression, but the underlying molecular tumourigenesis mechanisms remain largely unknown.
Z. Wu +18 more
semanticscholar +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT SETD2 has an essential role in epigenetic regulation. SETD2 pathogenic variants cause neurodevelopmental disorders (SETD2‐NDDs) that most commonly include various degrees of intellectual disability and behavioral disorders, macrocephaly, brain malformations, and generalized overgrowth.
Marie Lucain +11 more
wiley +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Prader‐Willi syndrome (PWS) is a neurodevelopmental disorder typically caused by large deletions or imprinting defects on chromosome 15q11.2, encompassing multiple genes. While the contribution of individual genes to the PWS phenotype remains unclear, previous studies suggested that isolated deletions of MAGEL2, NDN, and MKRN3, excluding the ...
Jannis Buecking +6 more
wiley +1 more source
Cohesins: Crossroad Between Cornelia de Lange Spectrum and Cancer Predisposition
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The cohesin complex plays crucial roles in DNA repair, chromatid separation, and gene transcription regulation. Pathogenic variants in cohesins or dysfunctional transcriptional regulators lead to cohesinopathies, a broader group of disorders including Cornelia de Lange Spectrum (CdLSp), for which the prevalence of cancer cases remains unclear.
Laura Rigotti +11 more
wiley +1 more source
Environmental Toxicology and Chemistry, Volume 42, Issue 1, Page 130-142, January 2023., 2023 Abstract Gene expression profiling in Caenorhabditis elegans has been demonstrated to be a potential bioanalytical tool to detect the toxic potency of environmental contaminants. The RNA transcripts of genes responding to toxic exposure can be used as biomarkers for detecting these toxins. For routine application in environmental quality monitoring, an
Antoine Karengera +4 more
wiley +1 more source
Feline hypersomatotropism and acromegaly tumorigenesis: a potential role for the AIP gene [PDF]
, 2017 Acromegaly in humans is usually sporadic, however up to 20% of familial isolated pituitary adenomas are caused by germline sequence variants of the aryl-hydrocarbon-receptor interacting protein (AIP) gene.
Catchpole, B +5 more
core +1 more source
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Residential proximity to commercial pesticide application has been associated with increased odds of developing chronic rhinosinusitis (CRS) with in vitro studies demonstrating cytotoxic dose‐dependent effects on sinonasal epithelia.
Melodyanne Y. Cheng +8 more
wiley +1 more source
A Novel International Endoscopic Sphenoid Surgery Classification (IESSC): A Delphi Consensus
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Advancements in endoscopic sinus and skull base surgery created a need for standardized terminology to describe sphenoid sinus surgery. Although classification systems exist for other sinuses, one for endoscopic sphenoid sinus surgery is lacking.
Hussain Albaharna +20 more
wiley +1 more source