Results 21 to 30 of about 770,455 (417)

Surgical Outcomes of Clival Chordoma Through Endoscopic Endonasal Approach: A Single-Center Experience

open access: yesFrontiers in Endocrinology, 2022
ObjectiveClival chordoma is a locally aggressive tumor with low metastatic potential. In the past decade, endoscopic endonasal approach (EEA) for clival chordoma has had a higher resection rate and a lower morbidity rate than transcranial approaches ...
Ge Chen   +13 more
doaj   +1 more source

High-resolution DCE-MRI of the pituitary gland using radial k-space acquisition with compressed sensing reconstruction [PDF]

open access: yes, 2015
BACKGROUND AND PURPOSE: The pituitary gland is located outside of the blood-brain barrier. Dynamic T1 weighted contrast enhanced sequence is considered to be the gold standard to evaluate this region.
Babb, J.   +8 more
core   +1 more source

Treatment of Aggressive Pituitary Adenomas: A Case-Based Narrative Review

open access: yesFrontiers in Endocrinology, 2021
Management of aggressive pituitary adenomas is challenging due to a paucity of rigorous evidence supporting available treatment approaches. Recent guidelines emphasize the need to maximize standard therapies as well as the use of temozolomide and ...
Odelia Cooper   +4 more
doaj   +1 more source

Vascular endothelial growth factor production and regulation in rodent and human pituitary tumor cells in vitro [PDF]

open access: yes, 2001
Angiogenesis, the formation of a new blood supply, is an essential step in tumorigenesis. Although vascular endothelial growth factor (VEGF) is known to be a very potent angiogenic factor in most solid tumors, little is known about its production and ...
Gloddek, Jutta   +7 more
core   +1 more source

Regulation of the Hypothalamic-Pituitary-Adrenocortical Stress Response.

open access: yesComprehensive Physiology, 2016
The hypothalamo-pituitary-adrenocortical (HPA) axis is required for stress adaptation. Activation of the HPA axis causes secretion of glucocorticoids, which act on multiple organ systems to redirect energy resources to meet real or anticipated demand ...
J. Herman   +7 more
semanticscholar   +1 more source

The Clinical and Pathological Characteristics of Refractory Pituitary Adenomas: A Single Center Experience

open access: yesFrontiers in Oncology, 2022
BackgroundMost of pituitary adenomas (PAs) are slow-growing benign tumors which can be cured or controlled by conventional therapies, including surgery, medical treatment or radiotherapy.
Xiaohai Liu   +17 more
doaj   +1 more source

European Society of Endocrinology Clinical Practice Guidelines for the management of aggressive pituitary tumours and carcinomas.

open access: yesEuropean Journal of Endocrinology, 2018
BACKGROUND Pituitary tumours are common and easily treated by surgery or medical treatment in most cases. However, a small subset of pituitary tumours does not respond to standard medical treatment and presents with multiple local recurrences (aggressive
G. Raverot   +7 more
semanticscholar   +1 more source

Preoperative Fasting C-Peptide Acts as a Promising Predictor of Improved Glucose Tolerance in Patients With Acromegaly After Transsphenoidal Surgery: A Retrospective Study of 64 Cases From a Large Pituitary Center in China

open access: yesFrontiers in Endocrinology, 2019
Purpose: Abnormal glucose metabolism is one of the most frequent acromegaly complications. Improvement of glucose metabolism can be observed only in half of acromegaly patients after surgery.
Zihao Wang   +17 more
doaj   +1 more source

Prediction of the Recurrence of Non-Functioning Pituitary Adenomas Using Preoperative Supra-Intra Sellar Volume and Tumor-Carotid Distance

open access: yesFrontiers in Endocrinology, 2021
BackgroundCurrently, it is difficult to estimate the possibility of recurrence of nonfunctioning pituitary adenomas (NFPAs). Markers such as Ki-67 or transcription factors rely on postoperative pathology, while few indices can be used for preoperative ...
Wenli Chen   +9 more
doaj   +1 more source

Gonadotropin and kisspeptin gene expression, but not GnRH, are impaired in cFOS deficient mice. [PDF]

open access: yes, 2015
cFOS is a pleiotropic transcription factor, which binds to the AP1 site in the promoter of target genes. In the pituitary gonadotropes, cFOS mediates induction of FSHβ and GnRH receptor genes.
Coss, Djurdjica   +3 more
core   +1 more source

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