Results 31 to 40 of about 574,474 (315)

Primary application of cavernous sinus cranial nerve neurophysiological monitoring in extended endoscopic transsphenoidal surgery

Chinese Journal of Contemporary Neurology and Neurosurgery, 2021
Objective To investigate the effect of neurophysiological monitoring in extended endoscopic transsphenoidal surgery for cavernous sinus and clivus tumors.
MAO Zhi⁃gang, WEI Xin, CHEN Jin⁃ping, LI Yong⁃fu, WANG Hai⁃jun   +4 more
doaj   +1 more source

Pituitary dysfunction induced by immune checkpoint inhibitors is associated with better overall survival in both malignant melanoma and non-small cell lung carcinoma: a prospective study

Journal for ImmunoTherapy of Cancer, 2020
Background Several immune-related adverse events (irAEs) are reported to be associated with therapeutic efficacy of immune checkpoint inhibitors, yet whether pituitary dysfunction, a life-threatening irAE, affects overall survival (OS) in patients with ...
Tomoko Kobayashi, Shintaro Iwama, Yoshinori Yasuda, N. Okada, Takayuki Okuji, Masaaki Ito, Takeshi Onoue, Motomitsu Goto, Mariko Sugiyama, T. Tsunekawa, Hiroshi Takagi, Daisuke Hagiwara, Yoshihiro Ito, Hidetaka Suga, Ryoichi Banno, K. Yokota, T. Hase, M. Morise, N. Hashimoto, M. Ando, Y. Fujimoto, H. Hibi, M. Sone, Y. Ando, M. Akiyama, Y. Hasegawa, H. Arima   +26 more
semanticscholar   +1 more source

Controlled Study of Pre‐ and Postoperative Headache in Patients with Sellar Masses (HEADs‐uP Study)

Endocrinology, Diabetes & Metabolism
Introduction Sellar masses are common intracranial neoplasms. Their clinical manifestations vary widely and include headache. We aimed to determine whether the prevalence and characteristics of headache in patients with sellar tumours differ from the ...
Tessa N. A. Slagboom, Tessel M. Boertien, Peter H. Bisschop, Eric Fliers, Johannes C. Baaijen, Jantien Hoogmoed, Madeleine L. Drent   +6 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Development of a Novel Algorithm to Identify People with High Likelihood of Adult Growth Hormone Deficiency in a US Healthcare Claims Database

International Journal of Endocrinology, 2022
Objective. Adult growth hormone deficiency (AGHD) is an underdiagnosed disease associated with increased morbidity and mortality. Identifying people who may benefit from growth hormone (GH) therapy can be challenging, as many AGHD symptoms resemble those
Kevin C. J. Yuen, Anna Camilla Birkegard, Lewis S. Blevins, David R. Clemmons, Andrew R. Hoffman, Nicky Kelepouris, Janice M. Kerr, Jens M. Tarp, Maria Fleseriu   +8 more
doaj   +1 more source

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

Arthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C. Scott   +3 more
wiley   +1 more source

Pathological characteristics of reoperated regrowing clinically nonfunctioning pituitary tumor cases in comparison with initial surgical cases

Frontiers in Endocrinology
ObjectivePostoperative nonfunctioning pituitary tumor (NFPT) regrowth is a significant concern, but its predictive factors are not well established. This study aimed to elucidate the pathological characteristics of NFPTs indicated for reoperation for ...
Atsushi Ishida, Naoko Inoshita, Noriaki Tanabe, Koji Takano, Sachiko Tanaka-Mizuno, Masataka Kato, Haruko Yoshimoto, Hideki Shiramizu, Go Matsuoka, Shozo Yamada   +9 more
doaj   +1 more source

Novel somatic variants involved in biochemical activity of pure growth hormone-secreting pituitary adenoma without GNAS variant

Scientific Reports, 2021
We aimed to identify somatic genetic alterations in pure growth hormone (GH)-secreting pituitary adenomas without GNAS variants. Patients with GH-secreting pituitary adenoma who underwent transsphenoidal adenomectomy at Severance Hospital, Yonsei ...
Cheol Ryong Ku, Hyeonseob Lim, Yang Jong Lee, Sun Ho Kim, Daham Kim, Se Hoon Kim, Mi Kyung Lee, Duhee Bang, Eun Jig Lee   +8 more
doaj   +1 more source

Beyond Inflammation: Why Understanding the Brain Matters in Inflammatory Arthritis

Arthritis Care &Research, EarlyView.
Persistent pain remains a major challenge in inflammatory arthritis, even when joint inflammation is well controlled. Pain and associated symptoms such as fatigue cannot be explained by peripheral inflammation alone but reflect altered central pain processing. These changes may arise through “top‐down” mechanisms, reflecting pre‐existing dysfunction in
Eoin M. Kelleher, Rosario Meouchi, Anushka Irani   +2 more
wiley   +1 more source

Non-functioning pituitary adenomas: indications for pituitary surgery and post-surgical management

Pituitary, 2019
PurposeNon-functioning pituitary adenomas (NFPAs) are associated with impaired well-being, increased comorbidities, and reduced long-term survival. Data on optimal management of NFPAs around surgical treatment are scarce, and postoperative treatment and ...
D. Esposito, Daniel S Olsson, O. Ragnarsson, M. Buchfelder, T. Skoglund, G. Johannsson   +5 more
semanticscholar   +1 more source