Results 31 to 40 of about 627,391 (362)
Genomic landscape of gliosarcoma: distinguishing features and targetable alterations
Scientific Reports, 2021 Gliosarcoma is an aggressive brain tumor with histologic features of glioblastoma (GBM) and soft tissue sarcoma. Despite its poor prognosis, its rarity has precluded analysis of its underlying biology.
Mark M. Zaki +8 more
doaj +1 more source
Trophic and neurotrophic factors in human pituitary adenomas (Review) [PDF]
, 2017 The pituitary gland is an organ that functionally connects the hypothalamus with the peripheral organs. The pituitary gland is an important regulator of body homeostasis during development, stress, and other processes.
Agostinelli, Enzo +11 more
core +1 more source
Inflammation-induced Gro1 triggers senescence in neuronal progenitors: effects of estradiol
Journal of Neuroinflammation, 2018 Background Inflammation has been proposed to contribute to the decline in adult hippocampal neurogenesis. Proinflammatory cytokines activate transcription of chemokine growth-regulated oncogene α (Gro1) in human and murine hippocampal neuronal progenitor
Svetlana Zonis +6 more
doaj +1 more source
Frontiers in Endocrinology, 2023 ObjectiveExcessive growth hormone and insulin-like growth factor 1 contribute to cutaneous changes in acromegaly. We investigated the sub-macroscopic skin manifestation of acromegaly patients and explored its reversibility upon hormone reduction after ...
Xiaopeng Guo +7 more
doaj +1 more source
E-cadherin expression is associated with somatostatin analogue response in acromegaly [PDF]
, 2018 Acromegaly is a rare disease resulting from hypersecretion of growth hormone (GH) and insulin‐like growth factor 1 (IGF1) typically caused by pituitary adenomas, which is associated with increased mortality and morbidity. Somatostatin analogues (SSAs)
Cano, David A. +10 more
core +1 more source
Frontiers in Endocrinology, 2021 Pituitary metastasis is an unusual situation in clinical practice, while the incidence is increasing with age. Breast cancer for women and lung cancer for men were the most frequent primary origins of pituitary metastasis.
Xiaohai Liu +7 more
doaj +1 more source
The role of stereotactic radiosurgery in the multimodal management of growth hormone–secreting pituitary adenomas [PDF]
, 2010 Growth hormone (GH)–secreting pituitary adenomas represent a common source of GH excess in patients with acromegaly. Whereas surgical extirpation of the culprit lesion is considered first-line treatment, as many as 19% of patients develop recurrent ...
Liu, Charles Y. +2 more
core +1 more source
Thyroxine-binding globulin: investigation of microheterogeneity [PDF]
, 1981 Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland +4 more
core +1 more source
Frontiers in Endocrinology, 2019 Background: Hypercortisolism has been implicated in the development of venous thromboembolic events (VTE). We aimed to characterize VTE risk in endogenous Cushing's syndrome (CS) patients, compare that risk to other pathologies, and determine if there ...
Jeffrey Wagner +6 more
doaj +1 more source
Chinese Journal of Contemporary Neurology and Neurosurgery, 2021 Objective To investigate the effect of neurophysiological monitoring in extended endoscopic transsphenoidal surgery for cavernous sinus and clivus tumors.
MAO Zhi⁃gang +4 more
doaj +1 more source