Results 241 to 250 of about 741,920 (302)
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Modelling the Pituitary Response to Luteinizing Hormone-Releasing Hormone
Journal of Neuroendocrinology, 2004AbstractThe pituitary response to luteinizing hormone‐releasing hormone (LHRH) is steroid‐dependent and varies throughout the reproductive cycle, but the rapid rise in pituitary sensitivity on the day of the ovulation‐inducing LH surge is due to a ‘self‐priming’ effect of exposure to LHRH that results in a potentiation of pituitary responsiveness 35–40
Gareth Leng
exaly +3 more sources
Growth hormone-releasing hormone and pituitary development, hyperplasia and tumorigenesis
Trends in Endocrinology and Metabolism, 2002Growth hormone-releasing hormone (GHRH) is essential for expansion of the somatotrope lineage during pituitary development, and excessive GHRH secretion and/or action results in unregulated somatotrope proliferation and neoplastic transformation. Our understanding of the molecular and morphological bases for these effects from both animal and clinical ...
Rhonda D Kineman, Lawrence A. Frohman
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Luteinizing Hormone-Releasing Hormone in Human Pituitary Blood
Obstetrical & Gynecological Survey, 1978✓ Luteinizing hormone (LH) and LH-releasing hormone (LHRH) were measured by radioimmunoassay in blood samples collected from the pituitary gland during transsphenoidal surgery in 19 patients. Detectable levels of LHRH were present in 12 patients. Wide fluctuations of LHRH were seen in sequential samples collected at 10-minute intervals, suggesting a ...
J L, Antunes +3 more
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Effects of cholinergic stimulation on pituitary hormone release
Psychoneuroendocrinology, 1982Abstract Physostigmine was infused into human volunteers to assess the effect of central cholinergic stimulation on memory and on neuroendocrine function. Methscopolamine bromide, a peripheral anticholinergic agent, was given simultaneously. The lower dose of physostigmine (1.0 mg) produced no change in AVP, cortisol, melatonin, GH or LH in those ...
B M, Davis +5 more
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The Journal of Clinical Endocrinology & Metabolism, 1983
In vitro evidence suggests that calcium is involved in the release of anterior pituitary hormones. Therefore, we studied the effect of the slow calcium channel blocker or calcium antagonist nifedipine on the FSH and LH responses to LRH and the TSH and PRL responses to TRH in vivo. Nine normal male subjects were studied on two occasions, and nifedipine
Struthers, A. D. +4 more
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In vitro evidence suggests that calcium is involved in the release of anterior pituitary hormones. Therefore, we studied the effect of the slow calcium channel blocker or calcium antagonist nifedipine on the FSH and LH responses to LRH and the TSH and PRL responses to TRH in vivo. Nine normal male subjects were studied on two occasions, and nifedipine
Struthers, A. D. +4 more
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Clinical Endocrinology, 1976
SummaryIntrajugular administration of LHRH (0.6 and 1.2 μg) in hypophysectomized rats which received renal grafts of anterior pituitary induced a small but significant rise in plasma GH 5 and 10 min post‐treatment. LHRH, at the same dose levels, was ineffective in weight‐matched intact controls.
Panerai A. E. +5 more
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SummaryIntrajugular administration of LHRH (0.6 and 1.2 μg) in hypophysectomized rats which received renal grafts of anterior pituitary induced a small but significant rise in plasma GH 5 and 10 min post‐treatment. LHRH, at the same dose levels, was ineffective in weight‐matched intact controls.
Panerai A. E. +5 more
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General and Comparative Endocrinology, 1977
The luteinizing hormone (LH) releasing activities of luteinizing hormone-releasing hormone (LH-RH) and four related analogues were compared using isolated chicken anterior pituitary cells. The analogues, des-Gly10-LH-RH and Phe5-LH-RH, exhibited a greater potency than LH-RH (150 and 237%, respectively), whereas LH-RH(OH) was much less active (1.1 ...
R C, Bonney, F J, Cunningham
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The luteinizing hormone (LH) releasing activities of luteinizing hormone-releasing hormone (LH-RH) and four related analogues were compared using isolated chicken anterior pituitary cells. The analogues, des-Gly10-LH-RH and Phe5-LH-RH, exhibited a greater potency than LH-RH (150 and 237%, respectively), whereas LH-RH(OH) was much less active (1.1 ...
R C, Bonney, F J, Cunningham
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Selectivity of Melatonin Pituitary Inhibition for Luteinizing Hormone-Releasing Hormone
Neuroendocrinology, 2008The pineal indole melatonin suppresses the neonatal rat luteinizing hormone (LH) and follicle-stimulating hormone (FSH) responses to LH-releasing hormone (LHRH), as shown in previous studies from this laboratory. We show in this study that the melatonin inhibition is a selective effect and is not due to general inhibition of pituitary function.
J E, Martin, C, Sattler
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Quantitative immunocytochemistry of pituitary receptors for luteinizing hormone-releasing hormone
Cell and Tissue Research, 1975In Araldite sections of male rat pituitaries, stained after embedding by the unlabeled antibody enzyme method with antisera to native luteinizing hormone-releasing hormone (LH-RH) or LH-RH azo-conjugated to bovine serum albumin, localization is confined mainly to the interior of the large, and to a lesser extent to that of the small, secretion granules
L A, Sternberger, J P, Petrali
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