Results 41 to 50 of about 741,920 (302)

Central hypothyroidism

Indian Journal of Endocrinology and Metabolism, 2011
Central hypothyroidism is defined as hypothyroidism due to insufficient stimulation by thyroid stimulating hormone (TSH) of an otherwise normal thyroid gland. It has an estimated prevalence of approximately 1 in 80,000 to 1 in 120,000.
Vishal Gupta, Marilyn Lee
doaj   +1 more source

Effect of Soyabean Isoflavones Exposure on Onset of Puberty, Serum Hormone Concentration and Gene Expression in Hypothalamus, Pituitary Gland and Ovary of Female Bama Miniature Pigs [PDF]

Asian-Australasian Journal of Animal Sciences, 2015
This study was to investigate the effect of soyabean isoflavones (SIF) on onset of puberty, serum hormone concentration, and gene expression in hypothalamus, pituitary and ovary of female Bama miniature pigs.
Juexin Fan, Bin Zhang, Lili Li, Chaowu Xiao, Oso Abimbola Oladele, Guoli Jiang, Hao Ding, Shengping Wang, Yueteng Xing, Dingfu Xiao, Yulong Yin   +10 more
doaj   +1 more source

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

Advanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang, Hongyu Zhu, Wenqi Wang, Bingqian Shen, Yuanyuan Xin, Xingxing Song, Xuanyi Lu, Lixuan Li, Siting Chen, Xiaochen Zhang, Jialing Zeng, Haodong Zheng, Jianlong Lao, Ke Peng, Yixian Wei, Jiaming Zheng, Chuanhuo Hu, Xiaoye Wang, Xun Li   +18 more
wiley   +1 more source

Day length regulates gonadotrope proliferation and reproduction via an intra-pituitary pathway in the model vertebrate Oryzias latipes

Communications Biology
In seasonally breeding mammals and birds, the production of the hormones that regulate reproduction (gonadotropins) is controlled by a complex pituitary-brain-pituitary pathway.
Muhammad Rahmad Royan, Kjetil Hodne, Rasoul Nourizadeh-Lillabadi, Finn-Arne Weltzien, Christiaan Henkel, Romain Fontaine   +5 more
doaj   +1 more source

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

Advanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo, Joe G. Rizk, Emilia Calvano, Rajesh Sahu, Emina Colovic, Imane Chabba, Valentine Gilbart, Erwan Grandgirard, Bastien Morlet, Qingshuang Cai, Daniel Metzger, Delphine Duteil   +11 more
wiley   +1 more source

Agmatine, a novel hypothalamic amine, stimulates pituitary luteinizing hormone release in vivo and hypothalamic luteinizing hormone-releasing hormone release in vitro

Neuroscience Letters, 1995
Agmatine, a clonidine displacing substance and imidazoline receptor agonist, was recently isolated from bovine brain and shown to be present in the rat hypothalamus. Since clonidine can stimulate the release of pituitary luteinizing hormone (LH), we tested the hypothesis that agmatine may similarly act in the rat to stimulate the hypothalamic ...
Department of Neuroscience, University of Florida College of Medicine, Box 100244, Gainesville, FL 32610-0244, USA ( host institution ), Kalra, Satya P. ( author ), Pearson, Edward ( author ), Sahu, Abhiram ( author ), Kalra, Pushpa S. ( author )   +4 more
openaire   +3 more sources

Multi‐Layer Transcriptomic Comparison Across Human, Pig, and Mouse Informs Tissue‐ and Trait‐Specific Animal Model Selection

Advanced Science, EarlyView.
We integrated RNA‐seq data from humans, pigs, and mice across 15 matched tissues based on 14 910 one‐to‐one orthologous genes. Cross‐species similarity was systematically evaluated across multiple regulatory layers, including global co‐expression conservation, co‐expression networks, tissue‐specific programs, and 3D genome architecture.
Jingwen Dou, Yong Liao, Xiong Shen, Xin Huang, Zhenshuang Tang, Yuwei Gou, Huajun Zhou, Jingya Xu, Hong Liu, Yue Wang, Keke Liang, Jia Liu, Xiao Zhang, Chenyao Li, Shangjian Wang, Liangliang Fu, Lilin Yin, Xinyun Li, Shuhong Zhao, Xiaolei Liu, Jingjin Li, Yuhua Fu   +21 more
wiley   +1 more source

The involvement of central corticotropin-releasing hormone and its receptors in sleep-wake regulation of mice [PDF]

, 2010
The corticotropin-releasing hormone (CRH) is widely recognised as the major activator of the hypothalamic-pituitary-adrenocortical (HPA) axis, thereby mediating neuroendocrine, autonomic, and behavioural responses to stress.
Romanowski, C., Romanowski, Christoph
core   +1 more source

Effects of tetramethyl bisphenol F on thyroid and growth hormone-related endocrine systems in zebrafish larvae

Ecotoxicology and Environmental Safety, 2022
Trimethyl bisphenol F (TMBPF) has recently been used as a bisphenol A substitute in polymer coatings for metal cans containing beverages or food. This study investigated whether TMBPF disrupts the endocrine system associated with thyroid hormones and ...
Hyunggyu Kim, Kyunghee Ji
doaj   +1 more source

Impact of Gene-Gender Effects of Adrenergic Polymorphisms on Hypothalamic-Pituitary-Adrenal Axis Activity in Depressed Patients [PDF]

, 2008
Objective: There is overwhelming evidence that activation of the hypothalamic-pituitary-adrenal (HPA) system plays a major role in depression and cardiovascular disease in genetically susceptible individuals.
Bondy, Brigitta, Baghai, Thomas C., Spraul, M., Zill, P., Rupprecht, R., Eser, D., Schule, C., Haefner, S.   +7 more
core   +1 more source