Lymphocytic infundibuloneurohypophysitis: A rare case report
Lymphocytic hypophysitis is a neuroendocrine disorder characterized by autoimmune infiammation of the pituitary gland with various degrees of pituitary dysfunction. Coexistence of other autoimmune conditions is reported in the vast majority of cases. The
Manish Gutch+4 more
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Functional anterior pituitary generated in self-organizing culture of human embryonic stem cells
It is difficult to generate functional human anterior pituitary tissues in vitro. Here, Ozone et al. generate human anterior pituitary from embryonic stem cells by recapitulating in vivodevelopment, and demonstrate this tissue secretes hormones and ...
Chikafumi Ozone+8 more
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Electrolyte Imbalance in Patients with Sheehan's Syndrome [PDF]
BackgroundWe investigated the prevalence of electrolyte imbalance and the relationship between serum electrolyte and anterior pituitary hormone levels in patients with Sheehan's syndrome.MethodsIn a retrospective study, we investigated 78 patients with ...
Chur Hoan Lim+7 more
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The effect of acute heat exposure on rat pituitary corticotroph activation: the role of vasopressin.
The increased ambient temperature affects the function of hypothalamic-pituitary-adrenal (HPA) axis. Since the correlation among vasopressin (VP), adrenocorticotropic hormone (ACTH) and corticosterone (CORT) responses to various stressors have been long ...
Sinisa Djurasevic+8 more
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Identification and clinical significance of folliculo-stellate cells in normal hypophysis and adenomas [PDF]
Background: Folliculo-stellate cells were first identified with electron microscopy as a non-hormone secreting accessory cells, star-shaped and follicleforming cells. They represent about 4-20% of pituitary cells from the anterior pituitary lobe.
Elena Portnoi
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Deprenyl, an old drug with new anticancer potential: Mini review [PDF]
The anticancer potential of monoamine oxidase (MAO) was observed in pre-clinical assays conducted with cell cultures and animals. L-Deprenyl (DEP) causes apoptosis in melanoma, leukemia and mammary cells. High-dose DEP has shown toxicity in mammary and pituitary cancers, as well as in monoblastic leukemia, in rats.
arxiv
ZBTB20 is required for anterior pituitary development and lactotrope specification
The pituitary is a complex structure with the anterior lobe containing five specialized cell types secreting different hormones. Here Cao et al. unravel a role for ZBTB20 in pituitary development and specifically in lactrotrope specification.
Dongmei Cao+16 more
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Successful twin pregnancy in panhypopituitarism
Panhypopituitarism is characterized by inadequate or absent production of anterior pituitary hormones. This involves hypofunction of most of the major endocrine functions that affect fertility and reproduction.
R. D. Jeewantha+3 more
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Mathematical Modelling of Hypothalamus-Pituitary-Adrenal Axis Dynamics: A Review, a Novel Approach, and Future [PDF]
A novel mathematical model for the hypothalamic pituitary adrenal (HPA) axis is proposed to comprehend the oscillations observed in hormone concentration and potential dysfunction within the HPA axis in stressful situation. This model integrates impact of hippocampal receptors on the secretion of corticotropin-releasing hormone (CRH), an additional ...
arxiv
DynPeak : An algorithm for pulse detection and frequency analysis in hormonal time series [PDF]
The endocrine control of the reproductive function is often studied from the analysis of luteinizing hormone (LH) pulsatile secretion by the pituitary gland. Whereas measurements in the cavernous sinus cumulate anatomical and technical difficulties, LH levels can be easily assessed from jugular blood.
arxiv +1 more source