Results 51 to 60 of about 64,206 (312)

Distinctive actions of connexin 46 and connexin 50 in anterior pituitary folliculostellate cells. [PDF]

open access: yesPLoS ONE, 2017
Folliculostellate cell gap junctions establish a network for the transmission of information within the anterior pituitary. Connexins make up gap junction channels.
María Leiza Vitale   +3 more
doaj   +1 more source

Isolated anterior pituitary dysfunction in adulthood

open access: yesFrontiers in Endocrinology, 2023
Hypopituitarism is defined as a complete or partial deficiency in one or more pituitary hormones. Anterior hypopituitarism includes secondary adrenal insufficiency, central hypothyroidism, hypogonadotropic hypogonadism, growth hormone deficiency and ...
Nunzia Prencipe   +8 more
doaj   +1 more source

The Processes of Anterior Pituitary Hormone Pulse Generation [PDF]

open access: yesEndocrinology, 2018
More than 60 years ago, Geoffrey Harris described his "neurohumoral theory," in which the regulation of pituitary hormone secretion was a "simple" hierarchal relationship, with the hypothalamus as the controller. In models based on this theory, the electrical activity of hypothalamic neurons determines the release of hypophysiotropic hormones into the ...
Le Tissier, Paul   +2 more
openaire   +3 more sources

PFOS Disrupts Oocyte Maturation and Early Embryonic Development via Ovarian FOXK1 O‐GlcNAcylation in Mice

open access: yesAdvanced Science, EarlyView.
Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han   +16 more
wiley   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

open access: yesAdvanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen   +8 more
wiley   +1 more source

Male reproductive hormones and semen quality

open access: yesAsian Pacific Journal of Reproduction, 2019
Male reproductive functions are mediated by different hormones whose orchestrations remain a major research interest. The ‘master’ regulator hormonal axis is the hypothalamo- pituitary-gonadal/testicular axis which is led by the pulsatile release of ...
Sulagna Dutta   +2 more
doaj   +1 more source

Claudin-9 constitutes tight junctions of folliculo-stellate cells in the anterior pituitary gland

open access: yesScientific Reports, 2021
The anterior pituitary gland regulates growth, metabolism, and reproduction by secreting hormones. Folliculo-stellate (FS) cells are non-endocrine cells located among hormone-producing cells in the anterior pituitary glands.
Atsuko Y. Higashi   +5 more
doaj   +1 more source

Soluble guanylyl cyclase α1 subunit is a key mediator of proliferation, survival, and migration in ECC-1 and HeLa cell lines [PDF]

open access: yes, 2019
Soluble guanylyl cyclase (sGC) is a heterodimeric enzyme constituted by two subunits, α1 and β1. Previously we have shown that 17β-estradiol (E2) exerts opposite effects on these subunits by increasing α1 and decreasing both β1 expression and enzymatic ...
Bollani, Sabrina Natalia   +6 more
core   +1 more source

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

open access: yesAdvanced Science, EarlyView.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen   +9 more
wiley   +1 more source

Unmasking the pituitary shadow 11 years postpartum: A case report of late-stage Sheehan's syndrome

open access: yesRadiology Case Reports
Sheehan's syndrome (SS) is a rare but significant condition that occurs as a result of postpartum pituitary gland infarction, typically following severe blood loss or hypotension during or after childbirth.
Oumaima Mesbah   +5 more
doaj   +1 more source

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