Results 51 to 60 of about 162,638 (311)
Epileptiform Activity and Seizure Risk Follow Long‐Term Non‐Linear Attractor Dynamics
Advanced Science, EarlyView.This study leverages the HAVOK framework to model long‐term, nonlinear attractor dynamics underlying epileptiform activity and seizure risk in epilepsy patients. By identifying key forcing mechanisms driving chaotic transitions, the findings improve seizure risk forecasting over multi‐day cycles and provide a pathway for personalized, data‐driven ...
Richard E Rosch +4 more
wiley +1 more source
Evaluation of Anterior Pituitary Leptin Receptor Expression in Pregnant and Non-pregnant Gilts [PDF]
, 2020 Successful reproduction in porcine depends on the coordinated synthesis and release of several hormones from the hypothalamus and anterior pituitary gland.
Clapper, Jeffrey, Pederson, Juliana
core +1 more source
Advanced Science, EarlyView.Chronic social stress elevates oxytocin levels, leading to immunosuppression by enhancing regulatory T‐cell activity and promoting anti‐inflammatory macrophage polarization in the spleen. Blocking oxytocin signaling reverses these effects but worsens stress‐induced behavioral disorders and reduces survival rates. This highlights oxytocin's dual role in
Yi‐Shu Zhang +5 more
wiley +1 more source
Clinical Features and Analysis in Pituitary Stalk Interruption Syndrome
International Journal of EndocrinologyObjective. Pituitary stalk interruption syndrome (PSIS) is characterized by the absence of pituitary stalk, pituitary hypoplasia, and ectopic posterior pituitary.
Qiuxuan Guo, Jing Zhao, Shuang Yu
doaj +1 more source
Mirtazapine decreases stimulatory effects of reboxetine on cortisol, adrenocorticotropin and prolactin secretion in healthy male subjects [PDF]
, 2004 Reboxetine is a selective noradrenaline reuptake inhibitor, whereas mirtazapine acts as an antagonist at noradrenergic alpha(2), serotonin (5-HT2), 5-HT3 and histamine H-1 receptors.
Baghai, Thomas C. +2 more
core +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Advanced Science, EarlyView.Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang +4 more
wiley +1 more source
Advances in computational modeling approaches in pituitary gonadotropin signaling [PDF]
Expert Opinion on Drug Discovery, 1-15. (2018), 2018 Pituitary gonadotropins play an essential and pivotal role in the control of human and animal reproduction within the hypothalamic-pituitary-gonadal (HPG) axis. The computational modeling of pituitary gonadotropin signaling encompasses phenomena of different natures such as the dynamic encoding of gonadotropin secretion, and the intracellular cascades ...
arxiv +1 more source
Advanced Science, EarlyView.RSPO2 and GDF9:BMP15 heterodimers—core components of oocyte‐secreted factors (OSFs)—coordinate to shape the molecular architecture of preantral granulosa cells via gene‐specific synergistic and antagonistic regulation, mediated through CTNNB1–SMAD2 signaling crosstalk.
Yingmei Wang +7 more
wiley +1 more source
BMC Endocrine Disorders, 2017 Background A functional pituitary adenoma can produce multiple anterior-pituitary hormones, such as growth hormone (GH) -producing adenomas (GHoma) with prolactin or thyrotropin stimulating hormone production in the same lineage. However, it is very rare
Tomoko Takiguchi +18 more
doaj +1 more source
3D Atlas of the Pituitary Gland of the Model Fish Medaka (Oryzias latipes)
Frontiers in Endocrinology, 2021 In vertebrates, the anterior pituitary plays a crucial role in regulating several essential physiological processes via the secretion of at least seven peptide hormones by different endocrine cell types.
Muhammad Rahmad Royan +8 more
doaj +1 more source