Results 111 to 120 of about 514,858 (318)

The Epigenomics of Pituitary Adenoma

open access: yesFrontiers in Endocrinology, 2019
Background: The vast majority of pituitary tumors are benign and behave accordingly; however, a fraction are invasive and are more aggressive, with a very small fraction being frankly malignant.
Blake M. Hauser   +4 more
doaj   +1 more source

Complications associated with microscopic and endoscopic transsphenoidal pituitary surgery: experience of 1153 consecutive cases treated at a single tertiary care pituitary center.

open access: yesJournal of Neurosurgery, 2019
OBJECTIVEPituitary adenomas (PAs) are benign neoplasms that are frequently encountered during workup for endocrinopathy, headache, or visual loss. Transsphenoidal surgery remains the first-line approach for PA resection.
Matthew S Agam   +5 more
semanticscholar   +1 more source

Progress on diagnosis and treatment of pituitary adenoma in children

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery
Pituitary adenoma is a benign intracranial tumor, commonly found in adults and occasionally in children. Pituitary adenoma is classified into secretory and non-secretory adenoma based on whether there is abnormal hormone secretion.
WANG Chuan-wei   +5 more
doaj   +1 more source

Biomarkers for Liquid Biopsies of Pituitary Neuroendocrine Tumors

open access: yesBiomedicines, 2020
Pituitary neuroendocrine tumors (PitNET) do not only belong to the most common intracranial neoplasms but seem to be generally more common than has been thought.
Wilhelm Gossing   +2 more
doaj   +1 more source

Corrin Ring Modification in Peptide Drug Development – a Brief History of “Corrination”

open access: yesChemMedChem, EarlyView.
This review highlights the applications of vitamin B12 conjugation (“corrination”) to peptides in the field of peptide‐based therapeutics, focusing on improved physio‐chemical properties, targeted/localized drug delivery, and enhanced oral bioavailability.
Nancy Cham, Robert P. Doyle
wiley   +1 more source

Continuous and Pulsed Experiments with Numerical Simulation to Dissect Pituitary Gland Tumour by Using Liquid Jet [PDF]

open access: yesEngineering Letters, 2017, 2019
Endoscopic endonasal surgery is a minimal invasive surgery that has been used to dissect pituitary gland tumour via curettes with the help of endoscope. However, this type of surgery has a high risk of failure because curettes may cause damages to blood vessels and optical nerves that lead to more complication for the patient.
arxiv  

Night‐Time Chronotherapy with Methylprednisolone Prevents an Acute Rejection in Pediatric Patients with Liver Transplantation: A Randomized Clinical Trial

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Concept of methylprednisolone chronotherapy to prevent acute rejections. While endogenous cortisol secretion rises in the early morning, the number of lymphocytes in the blood is higher at night, thus exhibiting an antiphase pattern to cortisol secretion. Therefore, compared with the daytime, the infiltration of lymphocytes into immune‐reactive tissues
Kentaro Ushijima   +11 more
wiley   +1 more source

Predictive value of pituitary tumor morphology on outcomes and complications in endoscopic transsphenoidal surgery

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 8, Issue 4, Page 321-329, December 2022., 2022
Abstract Purpose Endoscopic transsphenoidal surgery (ETSS) is an increasingly utilized approach for resection of pituitary tumors. Prior studies have evaluated preoperative tumor size, location, and extent as prognostic factors for surgical resection. There is little data on the relationship between preoperative pituitary tumor radiographic morphology ...
Andrew T. Heffernan   +8 more
wiley   +1 more source

Decreased Vision and Junctional Scotoma from Pituicytoma

open access: yesCase Reports in Ophthalmology, 2012
Pituicytomas are rare neoplasms of the sellar region. We report a case of vision loss and a junctional scotoma in a 43-year-old woman caused by compression of the optic chiasm by a pituitary tumor.
Nancy Huynh   +3 more
doaj   +1 more source

Pituitary Metastatic Composite Tumors: A Case Report with Next-Generation Sequencing and Review of the Literature

open access: yesCase Reports in Oncological Medicine, 2020
Background. While pituitary tumors are well understood, little research has been done on metastasis from primary tumors into pituitary adenomas, also known as composite tumors. Because only 34 cases of composite tumors have been reported to date, we hope
Matthew Helton   +5 more
doaj   +1 more source

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