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The Epigenomics of Pituitary Adenoma
Background: The vast majority of pituitary tumors are benign and behave accordingly; however, a fraction are invasive and are more aggressive, with a very small fraction being frankly malignant.
Blake M. Hauser+4 more
doaj +1 more source
OBJECTIVEPituitary adenomas (PAs) are benign neoplasms that are frequently encountered during workup for endocrinopathy, headache, or visual loss. Transsphenoidal surgery remains the first-line approach for PA resection.
Matthew S Agam+5 more
semanticscholar +1 more source
Progress on diagnosis and treatment of pituitary adenoma in children
Pituitary adenoma is a benign intracranial tumor, commonly found in adults and occasionally in children. Pituitary adenoma is classified into secretory and non-secretory adenoma based on whether there is abnormal hormone secretion.
WANG Chuan-wei+5 more
doaj +1 more source
Biomarkers for Liquid Biopsies of Pituitary Neuroendocrine Tumors
Pituitary neuroendocrine tumors (PitNET) do not only belong to the most common intracranial neoplasms but seem to be generally more common than has been thought.
Wilhelm Gossing+2 more
doaj +1 more source
Corrin Ring Modification in Peptide Drug Development – a Brief History of “Corrination”
This review highlights the applications of vitamin B12 conjugation (“corrination”) to peptides in the field of peptide‐based therapeutics, focusing on improved physio‐chemical properties, targeted/localized drug delivery, and enhanced oral bioavailability.
Nancy Cham, Robert P. Doyle
wiley +1 more source
Continuous and Pulsed Experiments with Numerical Simulation to Dissect Pituitary Gland Tumour by Using Liquid Jet [PDF]
Endoscopic endonasal surgery is a minimal invasive surgery that has been used to dissect pituitary gland tumour via curettes with the help of endoscope. However, this type of surgery has a high risk of failure because curettes may cause damages to blood vessels and optical nerves that lead to more complication for the patient.
arxiv
Concept of methylprednisolone chronotherapy to prevent acute rejections. While endogenous cortisol secretion rises in the early morning, the number of lymphocytes in the blood is higher at night, thus exhibiting an antiphase pattern to cortisol secretion. Therefore, compared with the daytime, the infiltration of lymphocytes into immune‐reactive tissues
Kentaro Ushijima+11 more
wiley +1 more source
Abstract Purpose Endoscopic transsphenoidal surgery (ETSS) is an increasingly utilized approach for resection of pituitary tumors. Prior studies have evaluated preoperative tumor size, location, and extent as prognostic factors for surgical resection. There is little data on the relationship between preoperative pituitary tumor radiographic morphology ...
Andrew T. Heffernan+8 more
wiley +1 more source
Decreased Vision and Junctional Scotoma from Pituicytoma
Pituicytomas are rare neoplasms of the sellar region. We report a case of vision loss and a junctional scotoma in a 43-year-old woman caused by compression of the optic chiasm by a pituitary tumor.
Nancy Huynh+3 more
doaj +1 more source
Background. While pituitary tumors are well understood, little research has been done on metastasis from primary tumors into pituitary adenomas, also known as composite tumors. Because only 34 cases of composite tumors have been reported to date, we hope
Matthew Helton+5 more
doaj +1 more source