Results 121 to 130 of about 66,700 (309)

Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. [PDF]

open access: yes, 2009
BRAF and NRAS are common targets for somatic mutations in benign and malignant neoplasms that arise from melanocytes situated in epithelial structures, and lead to constitutive activation of the mitogen-activated protein (MAP) kinase pathway.
Barsh, Gregory S   +8 more
core  

Arrhythmic expression signatures of circadian clock‐associated transcription factors and chronic circadian disruption contribute to advanced prostate cancer growth

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Circadian rhythm disruption potentially fuels prostate cancer progression. The mechanisms and signaling molecules contributing to hormonal tumorigenesis, however, remain largely undefined. In this study, circadian expression patterns of core‐circadian controlled genes (CCCGs) and nuclear receptors (NRs) were investigated in advanced ...
Ria Chopra   +4 more
wiley   +1 more source

Long‐term impact of stressful life events on breast cancer risk: A 36‐year genetically informed prospective study in the Finnish Twin Cohort

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Breast cancer results from a combination of genetic and environmental causes, and the cumulative effect of stressful life events may be a contributing factor. Here, the authors analyzed data from cohort and twin‐pair studies including 36 years of follow‐up to find out how stressful life events affect breast cancer risk. They found that even
Elissar Azzi   +5 more
wiley   +1 more source

Meningiomas occurring during long-term survival after treatment for childhood cancer

open access: yes, 2014
Childhood cancer is rare but improvements in treatment over the past five decades have resulted in a cohort of more than 30,000 long-term survivors of childhood cancer in the UK with more added annually.
Bhangoo, R.   +4 more
core   +1 more source

Microbiota‐gut‐brain axis multi‐organ chip construction and applications in drug evaluation

open access: yesiMetaOmics, EarlyView.
Microbiota‐gut‐brain axis multiorgan chip and its applications in drug evaluation. The chip includes essential biological components such as gut microbiota, gut barrier, blood‐brain barrier (BBB), and brain. This integrated platform incorporates neural (blue), endocrine (yellow), immune (pink), and metabolic (green) pathways to investigate the impact ...
Yue Tang   +9 more
wiley   +1 more source

The great simulator [PDF]

open access: yes, 1993
Cardiac myxoma often simulates multisystem disease and initially defies diagnosis. In this paper, we present three cases of cardiac myxoma in adults.
Aquilina, Oscar   +2 more
core  

Bifenthrin Under Scrutiny: Revisiting Toxicological Evidence Amid Regulatory Gaps

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Despite growing health concerns, bifenthrin (BF) remains widely used for controlling agricultural and residential pests. However, different perspectives on its toxicological profile and regulatory framework warrant a revisit and update on BF regulation towards a robust risk‐safety assessment.
Caroline V. L. Moreira   +10 more
wiley   +1 more source

Analysis of the experimental absorption spectrum of the rabbit lung and identification of its components

open access: yesJournal of Biophotonics, EarlyView.
The broadband absorption coefficient spectrum of the rabbit lung was reconstructed from the absorption spectra of tissue components. The similar accumulation of melanin and lipofuscin was retrieved from the broadband baseline in the absorption coefficient spectrum, and the calculation of the absorption fold ratios for proteins, DNA and hemoglobin ...
Maria R. Pinheiro   +2 more
wiley   +1 more source

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