Results 31 to 40 of about 66,700 (309)

Comprehensive Genomic Characterization of A Case of Granular Cell Tumor of the Posterior Pituitary Gland: A Case Report

Frontiers in Endocrinology, 2021
Granular cell tumors of the pituitary belong to a rare family of neoplasms, arising from the posterior pituitary gland. Although considered benign, they may cause significant morbidity and residual disease after resection can lead to poor clinical ...
Christopher S. Hong, Aladine A. Elsamadicy, Adeniyi Fisayo, Silvio E. Inzucchi, Pallavi P. Gopal, Eugenia M. Vining, E. Zeynep Erson-Omay, Sacit Bulent Omay   +7 more
doaj   +1 more source

Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors [PDF]

, 2016
PURPOSE: Subsets of pituitary tumors exhibit an aggressive clinical courses and recur despite surgery, radiation, and chemotherapy. Because modulation of the immune response through inhibition of T-cell checkpoints has led to durable clinical responses ...
Agar, Nathalie Y. R., Bi, Wenya Linda, Du, Ziming, Dunn, Gavin P, Dunn, Ian F, Fecci, Peter E, Freeman, Gordon J, Greenwald, Noah F, Kaiser, Ursula B, Laws, Edward R, Jr, Mei, Yu, Reardon, David A, Santagata, Sandro, Woodmansee, Whitney W   +13 more
core   +3 more sources

The evolution in pituitary tumour classification: a clinical perspective

Endocrine Oncology, 2023
Objective: Pituitary tumours comprise a pathologically and clinically diverse group of neoplasms. Classification frameworks have changed dramatically in the past two decades, reflecting improving understanding of tumour biology.
Nele F Lenders, Peter E Earls, Warrick J Inder, Ann I McCormack   +3 more
doaj   +1 more source

Chromogranin A as serum marker for neuroendocrine neoplasia: comparison with neuron-specific enolase and the alpha-subunit of glycoprotein hormones [PDF]

, 1997
Chromogranin A (CgA) is gaining acceptance as a serum marker of neuroendocrine tumors. Its specificity in differentiating between neuroendocrine and nonneuroendocrine tumors, its sensitivity to detect small tumors, and its clinical ...
Bouillon, R. (Roger), Coopmans, W., Herder, W.W. (Wouter) de, Krenning, E.P. (Eric), Kwekkeboom, D.J. (Dirk Jan), Lamberts, S.W.J. (Steven), Lindemans, J. (Jan), Nobels, F.R.E. (Frank), Schoenmakers, C.H.H. (Christian)   +8 more
core   +4 more sources

Chromogranin A: From Laboratory to Clinical Aspects of Patients with Neuroendocrine Tumors [PDF]

, 2018
Background. Neuroendocrine tumors (NETs) are characterized by having behavior and prognosis that depend upon tumor histology, primary site, staging, and proliferative index.
Baldelli, Roberto, Campana, Davide, Di Giacinto, Paola, Isidori, Andrea, Lania, Andrea, Lenzi, Andrea, Rizza, Laura, Rota, Francesca, Zuppi, Paolo   +8 more
core   +1 more source

Identification of Differentially Expressed Genes in Pituitary Adenomas by Integrating Analysis of Microarray Data

International Journal of Endocrinology, 2015
Pituitary adenomas, monoclonal in origin, are the most common intracranial neoplasms. Altered gene expression as well as somatic mutations is detected frequently in pituitary adenomas.
Peng Zhao, Wei Hu, Hongyun Wang, Shengyuan Yu, Chuzhong Li, Jiwei Bai, Songbai Gui, Yazhuo Zhang   +7 more
doaj   +1 more source

Relapse of the pituitary adenoma with a change of its hormonal activity in a female patient with multiple endocrine neoplasia syndrome type 1

Alʹmanah Kliničeskoj Mediciny, 2018
Multiple endocrine neoplasia syndrome type 1 (MEN1, Wermer's syndrome) is a group of heterogeneous inherited diseases, with its pathogenesis related to hyperplasia or neoplasms of several endocrine glands.
L. Ya. Rozhinskaya, P. M. Khandaeva, A. S. Lutsenko, A. M. Lapshina, A. Yu. Grigor'ev, S. D. Arapova, Zh. E. Belaya, G. A. Mel'nichenko   +7 more
doaj   +1 more source

Targeted treatment with somatostatin analogues: widening horizons of clinical practice

Alʹmanah Kliničeskoj Mediciny, 2022
Targeted treatment with somatostatin analogues (SA) in acromegaly and neuroendocrine neoplasms may have some benefits compared to curative treatments, because these agents decrease excessive hormone secretion and exert a tumor-suppressive effect ...
Vyacheslav S. Pronin, Mikhail B. Antsiferov, Tatiana M. Alexeeva, Evgeny V. Pronin   +3 more
doaj   +1 more source

Possible role of GADD45γ methylation in diffuse large B-cell Lymphoma: Does it affect the progression and tissue involvement? [PDF]

, 2015
Objective: Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma among adults and is characterized by heterogeneous clinical, immunophenotypic, and genetic features.
Barış, İkbal Cansu, Bağcı, Gülseren, Can, Özge, Caner, Vildan, Doğu, Mehmet Hilmi, Hacıoğlu, Sibel, Keskin, Ali, Sarı, İsmail, Tepeli, Emre, Türk, Nilay Şen, Çetin, Ozan   +10 more
core   +2 more sources

The Impact of Surgical Telementoring on Reducing the Complication Rate in Endoscopic Endonasal Surgery of the Skull Base

Diagnostics
Background: Pituitary adenomas represent the most common pituitary disorder, with an estimated prevalence as high as 20%, and they can manifest with hormone hypersecretion or deficiency, neurological symptoms from mass effect, or incidental findings on ...
Janez Ravnik, Hojka Rowbottom, Carl H. Snyderman, Paul A. Gardner, Tomaž Šmigoc, Matic Glavan, Urška Kšela, Nenad Kljaić, Boštjan Lanišnik   +8 more
doaj   +1 more source