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Biological and Therapeutic Implications of the Tumor Microenvironment in Pituitary Adenomas. [PDF]

Endocrine reviews, 2022
Pituitary adenomas are neoplasms derived from the endocrine cells of the anterior pituitary gland. Most frequently, they are benign tumors, but may sometimes display an aggressive course, and in some cases metastasize. Their biology, including their wide
M. Ilie, A. Vasiljevic, P. Bertolino, G. Raverot   +3 more
semanticscholar   +2 more sources

Glymphatic transport is reduced in rats with spontaneous pituitary tumor [PDF]

Frontiers in Medicine, 2023
Background and objectivePituitary tumor in patients induces adverse alterations in the brain, accompanied by cognitive deficits. Dysfunction of glymphatic waste clearance results in accumulation of neurotoxic products within the brain, leading to ...
Lian Li, Guangliang Ding, Li Zhang, Hao Luo, Esmaeil Davoodi-Bojd, Qingjiang Li, Michael Chopp, Michael Chopp, Zheng Gang Zhang, Quan Jiang, Quan Jiang   +10 more
doaj   +2 more sources

Evaluating pituitary tumor management: aligning with pituitary tumor centers of excellence criteria. [PDF]

Pituitary
Yang JH, Wang WH, Chen HS.
europepmc   +2 more sources

Imaging of pituitary tumors: an update with the 5th WHO Classifications—part 1. Pituitary neuroendocrine tumor (PitNET)/pituitary adenoma

Japanese Journal of Radiology, 2023
The pituitary gland is the body’s master gland of the endocrine glands. Although it is a small organ, many types of tumors can develop within it. The recently revised fifth edition of the World Health Organization (WHO) classifications (2021 World Health
Taro Tsukamoto, Yukio Miki
semanticscholar   +1 more source

Clinical Efficacy of Temozolomide and Its Predictors in Aggressive Pituitary Tumors and Pituitary Carcinomas: A Systematic Review and Meta-Analysis

Frontiers in Neurology, 2021
Background: A growing number of evidences suggest that TMZ applications can generate impressive benefits for APT and PC patients. However, the definite role of TMZ for individuals remains unclarified due to the variation between studies.
Mei Luo, Yiheng Tan, Wenli Chen, Bin Hu, Zongming Wang, Diming Zhu, Haosen Jiao, Chengbin Duan, Yonghong Zhu, Haijun Wang   +9 more
doaj   +1 more source

Automatic Detection for Acromegaly Using Hand Photographs: A Deep-Learning Approach

IEEE Access, 2021
Machine learning assisted diagnosis of acromegaly from facial photographs has been proved feasible in recent years. According to our previous research, facial and limb changes exist in patients with acromegaly at early stage.
Chengbin Duan, Wenli Chen, Shun Yao, Zhigang Mao, Zongming Wang, Bin Hu, Haosen Jiao, Dimin Zhu, Yonghong Zhu, Haijun Wang   +9 more
doaj   +1 more source

Spinning magnetic field patterns that cause oncolysis by oxidative stress in glioma cells

Scientific Reports, 2023
Raising reactive oxygen species (ROS) levels in cancer cells to cause macromolecular damage and cell death is a promising anticancer treatment strategy. Observations that electromagnetic fields (EMF) elevate intracellular ROS and cause cancer cell death,
Shashank Hambarde, Jeanne M. Manalo, David S. Baskin, Martyn A. Sharpe, Santosh A. Helekar   +4 more
doaj   +1 more source

Hydroxychloroquine overcomes cabergoline resistance in a patient with Lactotroph Pituitary neuroendocrine tumor: a case report

Frontiers in Endocrinology, 2022
ObjectiveA 22-year-old man complaining erectile dysfunction underwent transsphenoidal surgery for a 2.7 cm sellar mass with total resection and was confirmed at pathology to have a lactotroph pituitary neuroendocrine tumor (PiNET).
Shaojian Lin, Changxi Han, Xiaohui Lou, Zhe Bao Wu   +3 more
doaj   +1 more source

Risk of new tumor, carotid stenosis, and stroke after stereotactic radiosurgery for pituitary tumor: A multicenter study of 2254 patients with imaging follow-up. [PDF]

Neuro Oncol
Dumot C, Mantziaris G, Dayawansa S, Brantley C, Lee CC, Yang HC, Peker S, Samanci Y, Mathieu D, Tourigny JN, Martinez Moreno N, Martinez Alvarez R, Chytka T, Liscak R, Speckter H, Lazo E, Brito A, Picozzi P, Franzini A, Alzate J, Mashiach E, Bernstein K, Kondziolka D, Tripathi M, Bowden GN, Warnick RE, Sheehan D, Sheehan K, Fuentes A, Jane JA, Vance ML, Sheehan JP.   +31 more
europepmc   +3 more sources

Novel somatic variants involved in biochemical activity of pure growth hormone-secreting pituitary adenoma without GNAS variant

Scientific Reports, 2021
We aimed to identify somatic genetic alterations in pure growth hormone (GH)-secreting pituitary adenomas without GNAS variants. Patients with GH-secreting pituitary adenoma who underwent transsphenoidal adenomectomy at Severance Hospital, Yonsei ...
Cheol Ryong Ku, Hyeonseob Lim, Yang Jong Lee, Sun Ho Kim, Daham Kim, Se Hoon Kim, Mi Kyung Lee, Duhee Bang, Eun Jig Lee   +8 more
doaj   +1 more source