Results 31 to 40 of about 3,152,858 (268)

Evolution of Minimally Invasive Approaches to the Sella and Parasellar Region

International Archives of Otorhinolaryngology, 2014
Introduction Given advancements in endoscopic image quality, instrumentation, surgical navigation, skull base closure techniques, and anatomical understanding, the endonasal endoscopic approach has rapidly evolved into a widely utilized technique for ...
Robert G. Louis, Amy Eisenberg, Garni Barkhoudarian, Chester Griffiths, Daniel F. Kelly   +4 more
doaj   +1 more source

How to Classify and Define Pituitary Tumors: Recent Advances and Current Controversies

Frontiers in Endocrinology, 2021
Pituitary tumors are very complex and heterogeneous and have a very wide range of proliferative and aggressive behaviors, and how to define and classify these tumors remains controversial.
Congxin Dai, Jun Kang, Xiaohai Liu, Yong Yao, Yong Yao, Haijun Wang, Haijun Wang, Renzhi Wang, Renzhi Wang   +8 more
doaj   +1 more source

Intelligent Model for Brain Tumor Identification Using Deep Learning

Applied Computational Intelligence and Soft Computing, 2022
Brain tumors can be a major cause of psychiatric complications such as depression and panic attacks. Quick and timely recognition of a brain tumor is more effective in tumor healing.
Abdul Hannan Khan, Sagheer Abbas, Muhammad Adnan Khan, Umer Farooq, W. Khan, S. Siddiqui, Aiesha Ahmad   +6 more
semanticscholar   +1 more source

Autocrine IL-6 mediates pituitary tumor senescence

OncoTarget, 2016
Cellular senescence is a stable proliferative arrest state. Pituitary adenomas are frequent and mostly benign, but the mechanism for this remains unknown. IL-6 is involved in pituitary tumor progression and is produced by the tumoral cells.
M. Sapochnik, M. Haedo, Mariana Fuertes, P. Ajler, G. Carrizo, A. Cervio, G. Sevlever, G. Stalla, E. Arzt   +8 more
semanticscholar   +1 more source

Successful Treatment of Intracranial Glioblastoma Xenografts With a Monoamine Oxidase B-Activated Pro-Drug

EBioMedicine, 2015
The last major advance in the treatment of glioblastoma multiforme (GBM) was the introduction of temozolomide in 1999. Treatment with temozolomide following surgical debulking extends survival rate compared to radiotherapy and debulking alone.
Martyn A. Sharpe, Andrew D. Livingston, Taylor L. Gist, Pardip Ghosh, Junyan Han, David S. Baskin   +5 more
doaj   +1 more source

Impact of Pituitary Stalk Preservation on Tumor Recurrence/Progression and Surgically Induced Endocrinopathy After Endoscopic Endonasal Resection of Suprasellar Craniopharyngiomas

Frontiers in Neurology, 2021
Objective: To investigate the factors associated with recurrence/progression after endoscopic endonasal resection of suprasellar craniopharyngiomas.
Zhengyuan Chen, Zhengyuan Chen, Zhengyuan Chen, Zhengyuan Chen, Zhengyuan Chen, Zhengyuan Chen, Zengyi Ma, Zengyi Ma, Zengyi Ma, Zengyi Ma, Zengyi Ma, Zengyi Ma, Wenqiang He, Wenqiang He, Wenqiang He, Wenqiang He, Wenqiang He, Wenqiang He, Xuefei Shou, Xuefei Shou, Xuefei Shou, Xuefei Shou, Xuefei Shou, Xuefei Shou, Zhao Ye, Zhao Ye, Zhao Ye, Zhao Ye, Zhao Ye, Zhao Ye, Yichao Zhang, Yichao Zhang, Yichao Zhang, Yichao Zhang, Yichao Zhang, Yichao Zhang, Qilin Zhang, Qilin Zhang, Qilin Zhang, Qilin Zhang, Qilin Zhang, Qilin Zhang, Nidan Qiao, Nidan Qiao, Nidan Qiao, Nidan Qiao, Nidan Qiao, Nidan Qiao, Xiang Zhou, Xiang Zhou, Xiang Zhou, Xiang Zhou, Xiang Zhou, Xiang Zhou, Xiaoyun Cao, Xiaoyun Cao, Xiaoyun Cao, Xiaoyun Cao, Xiaoyun Cao, Xiaoyun Cao, Min He, Min He, Zhaoyun Zhang, Zhaoyun Zhang, Hongying Ye, Hongying Ye, Yiming Li, Yiming Li, Shiqi Li, Shiqi Li, Shiqi Li, Shiqi Li, Shiqi Li, Shiqi Li, Yao Zhao, Yao Zhao, Yao Zhao, Yao Zhao, Yao Zhao, Yao Zhao, Ming Shen, Ming Shen, Ming Shen, Ming Shen, Ming Shen, Ming Shen, Yongfei Wang, Yongfei Wang, Yongfei Wang, Yongfei Wang, Yongfei Wang, Yongfei Wang, Yongfei Wang   +92 more
doaj   +1 more source

The effects of somatostatin analogue therapy on pituitary tumor volume in patients with acromegaly

Pituitary, 2015
IntroductionIn nearly all cases, acromegaly is caused by excess GH from a pituitary adenoma, resulting in elevated circulating levels of GH and, subsequently, IGF-1. Treatment goals are to eliminate morbidity and restore the increased mortality to normal
A. Colao, R. Auriemma, R. Pivonello
semanticscholar   +1 more source

Tumor microenvironment defines the invasive phenotype of AIP-mutation-positive pituitary tumors

Oncogene, 2019
The molecular mechanisms leading to aryl hydrocarbon receptor interacting protein (AIP) mutation-induced aggressive, young-onset growth hormone-secreting pituitary tumors are not fully understood.
Sayka Barry, E. Carlsen, P. Marques, C. Stiles, Emanuela Gadaleta, D. Berney, F. Roncaroli, C. Chelala, A. Solomou, M. Herincs, F. Caimari, A. Grossman, T. Crnogorac-Jurcevic, O. Haworth, C. Gaston-Massuet, M. Korbonits   +15 more
semanticscholar   +1 more source

The PTTG1-targeting miRNAs miR-329, miR-300, miR-381, and miR-655 inhibit pituitary tumor cell tumorigenesis and are involved in a p53/PTTG1 regulation feedback loop

OncoTarget, 2015
Deregulation of the pituitary tumor transforming gene (PTTG1), a newly discovered oncogene, is a hallmark of various malignancies, including pituitary tumors. However, the mechanisms regulating PTTG1 expression are still needed to be explored. MicroRNAs (
Hai-qian Liang, Ren-jie Wang, Cai-feng Diao, Jianwei Li, Jing-liang Su, Sai Zhang   +5 more
semanticscholar   +1 more source

Brain tumor detection using artificial convolutional neural networks [PDF]

arXiv, 2022
In this paper, a convolutional neural network (CNN) was used to classify NMR images of human brains with 4 different types of tumors: meningioma, glioma and pituitary gland tumors. During the training phase of this project, an accuracy of 100% was obtained, meanwhile, in the evaluation phase the precision was 96%.
arxiv