Results 31 to 40 of about 3,292,689 (405)

Rotating Magnetic Fields Inhibit Mitochondrial Respiration, Promote Oxidative Stress and Produce Loss of Mitochondrial Integrity in Cancer Cells

Frontiers in Oncology, 2021
Electromagnetic fields (EMF) raise intracellular levels of reactive oxygen species (ROS) that can be toxic to cancer cells. Because weak magnetic fields influence spin state pairing in redox-active radical electron pairs, we hypothesize that they disrupt
Martyn A. Sharpe, Martyn A. Sharpe, Martyn A. Sharpe, David S. Baskin, David S. Baskin, David S. Baskin, David S. Baskin, Kumar Pichumani, Kumar Pichumani, Kumar Pichumani, Kumar Pichumani, Omkar B. Ijare, Omkar B. Ijare, Omkar B. Ijare, Santosh A. Helekar, Santosh A. Helekar, Santosh A. Helekar, Santosh A. Helekar   +17 more
doaj   +1 more source

Work disability and its determinants in patients with pituitary tumor-related disease

Pituitary, 2018
IntroductionPituitary tumors may have a considerable impact on patients’ functional status, including paid employment, yet research in this area is sparse.ObjectiveTo describe work disability and its determinants in patients treated for a pituitary tumor.
Daniel J. Lobatto, Anath N V Steffens, A. Z. Zamanipoor Najafabadi, C. Andela, A. Pereira, W. B. van den Hout, W. Peul, T. V. Vliet Vlieland, N. Biermasz, W. V. van Furth   +9 more
semanticscholar   +1 more source

Evolution of Minimally Invasive Approaches to the Sella and Parasellar Region

International Archives of Otorhinolaryngology, 2014
Introduction Given advancements in endoscopic image quality, instrumentation, surgical navigation, skull base closure techniques, and anatomical understanding, the endonasal endoscopic approach has rapidly evolved into a widely utilized technique for ...
Robert G. Louis, Amy Eisenberg, Garni Barkhoudarian, Chester Griffiths, Daniel F. Kelly   +4 more
doaj   +1 more source

How to Classify and Define Pituitary Tumors: Recent Advances and Current Controversies

Frontiers in Endocrinology, 2021
Pituitary tumors are very complex and heterogeneous and have a very wide range of proliferative and aggressive behaviors, and how to define and classify these tumors remains controversial.
Congxin Dai, Jun Kang, Xiaohai Liu, Yong Yao, Yong Yao, Haijun Wang, Haijun Wang, Renzhi Wang, Renzhi Wang   +8 more
doaj   +1 more source

Thyroxine-binding globulin: investigation of microheterogeneity [PDF]

, 1981
Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland, Henze, R., Horn, K., Pickardt, C. R., Scriba, Peter Christian   +4 more
core   +1 more source

Tumor microenvironment defines the invasive phenotype of AIP-mutation-positive pituitary tumors

Oncogene, 2019
The molecular mechanisms leading to aryl hydrocarbon receptor interacting protein (AIP) mutation-induced aggressive, young-onset growth hormone-secreting pituitary tumors are not fully understood.
Sayka Barry, E. Carlsen, P. Marques, C. Stiles, E. Gadaleta, D. Berney, F. Roncaroli, C. Chelala, A. Solomou, M. Herincs, F. Caimari, A. Grossman, T. Crnogorac-Jurcevic, O. Haworth, C. Gaston-Massuet, M. Korbonits   +15 more
semanticscholar   +1 more source

Successful Treatment of Intracranial Glioblastoma Xenografts With a Monoamine Oxidase B-Activated Pro-Drug

EBioMedicine, 2015
The last major advance in the treatment of glioblastoma multiforme (GBM) was the introduction of temozolomide in 1999. Treatment with temozolomide following surgical debulking extends survival rate compared to radiotherapy and debulking alone.
Martyn A. Sharpe, Andrew D. Livingston, Taylor L. Gist, Pardip Ghosh, Junyan Han, David S. Baskin   +5 more
doaj   +1 more source

Corticotropinoma as a Component of Carney Complex. [PDF]

, 2017
Known germline gene abnormalities cause one-fifth of the pituitary adenomas in children and adolescents, but, in contrast with other pituitary tumor types, the genetic causes of corticotropinomas are largely unknown.
Chittiboina, Prashant, Dimopoulos, Aggeliki, Faucz, Fabio R, Hernández-Ramírez, Laura C, Kay, Denise M, Lane, John, Lodish, Maya B, Mills, James L, Pankratz, Nathan, Stratakis, Constantine A, Tatsi, Christina, Valdés, Nuria   +11 more
core   +2 more sources

Impact of Pituitary Stalk Preservation on Tumor Recurrence/Progression and Surgically Induced Endocrinopathy After Endoscopic Endonasal Resection of Suprasellar Craniopharyngiomas

Frontiers in Neurology, 2021
Objective: To investigate the factors associated with recurrence/progression after endoscopic endonasal resection of suprasellar craniopharyngiomas.
Zhengyuan Chen, Zhengyuan Chen, Zhengyuan Chen, Zhengyuan Chen, Zhengyuan Chen, Zhengyuan Chen, Zengyi Ma, Zengyi Ma, Zengyi Ma, Zengyi Ma, Zengyi Ma, Zengyi Ma, Wenqiang He, Wenqiang He, Wenqiang He, Wenqiang He, Wenqiang He, Wenqiang He, Xuefei Shou, Xuefei Shou, Xuefei Shou, Xuefei Shou, Xuefei Shou, Xuefei Shou, Zhao Ye, Zhao Ye, Zhao Ye, Zhao Ye, Zhao Ye, Zhao Ye, Yichao Zhang, Yichao Zhang, Yichao Zhang, Yichao Zhang, Yichao Zhang, Yichao Zhang, Qilin Zhang, Qilin Zhang, Qilin Zhang, Qilin Zhang, Qilin Zhang, Qilin Zhang, Nidan Qiao, Nidan Qiao, Nidan Qiao, Nidan Qiao, Nidan Qiao, Nidan Qiao, Xiang Zhou, Xiang Zhou, Xiang Zhou, Xiang Zhou, Xiang Zhou, Xiang Zhou, Xiaoyun Cao, Xiaoyun Cao, Xiaoyun Cao, Xiaoyun Cao, Xiaoyun Cao, Xiaoyun Cao, Min He, Min He, Zhaoyun Zhang, Zhaoyun Zhang, Hongying Ye, Hongying Ye, Yiming Li, Yiming Li, Shiqi Li, Shiqi Li, Shiqi Li, Shiqi Li, Shiqi Li, Shiqi Li, Yao Zhao, Yao Zhao, Yao Zhao, Yao Zhao, Yao Zhao, Yao Zhao, Ming Shen, Ming Shen, Ming Shen, Ming Shen, Ming Shen, Ming Shen, Yongfei Wang, Yongfei Wang, Yongfei Wang, Yongfei Wang, Yongfei Wang, Yongfei Wang, Yongfei Wang   +92 more
doaj   +1 more source

Gene Expression and the Physiological Role of Transforming Growth Factor-α in the Mouse Pituitary [PDF]

, 2003
Transforming growth factor-alpha (TGF-alpha), a member of the epidermal growth factor (EGF) family, is produced within the mouse anterior pituitaries. However, the cell types of TGF-alpha-expressing cells and the physiological roles of TGF-a within mouse
Kakeya, Tomoshi, Masui, Tohru, Oomizu, Souichi, Sharma, Seema, Takahashi, Sumio, Takeuchi, Sakae   +5 more
core   +1 more source