Results 91 to 100 of about 322,068 (275)

Liberated PKA Catalytic Subunits Associate with the Membrane via Myristoylation to Preferentially Phosphorylate Membrane Substrates

open access: yesCell Reports, 2017
Summary: Protein kinase A (PKA) has diverse functions in neurons. At rest, the subcellular localization of PKA is controlled by A-kinase anchoring proteins (AKAPs). However, the dynamics of PKA upon activation remain poorly understood.
Shane E. Tillo   +10 more
doaj   +1 more source

Mechanistic studies of anti-hyperpigmentary compounds: elucidating their inhibitory and regulatory actions. [PDF]

open access: yes, 2014
Searching for depigmenting agents from natural sources has become a new direction in the cosmetic industry as natural products are generally perceived as relatively safer.
Cheng, CH   +3 more
core   +2 more sources

Bioinspired Polypeptide Dendrimer‐Modified Thin‐Film Composite Membranes for Selective Lithium‐Magnesium Separation with DFT Insights

open access: yesAdvanced Functional Materials, EarlyView.
We fabricated a biomimetic dendrimer‐modified thin‐film nanocomposite membrane with a coordination‐assisted ion‐selective interface. pH‐responsive polypeptide sites preferentially bind Mg2+ and promote Li+ permeation, as predicted by density functional theory calculations of metal‐ligand interactions.
Mehrasa Yassari   +7 more
wiley   +1 more source

Spectrophotometric Determination of Acidity Constants of Thiamine in Water, Water-Triton X-100 Micellar Media Solutions [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2008
In this work the acidity constants of Thiamine in water and water-Triton X-100 micelle media solutions, at 25 °C, have been determined spectrophotometrically.
Mohammad Goodarzi, Tahmineh Goodarzi
doaj  

Mechanically Stable and Tunable Photoactivated Peptide‐Based Hydrogels for Soft Tissue Adhesion

open access: yesAdvanced Functional Materials, EarlyView.
A collagen‐like peptide hydrogel platform is developed using supramolecular self‐assembly and light‐triggered crosslinking. It creates mechanically stable, tunable hydrogels with cytocompatibility and biodegradability, making them potential soft tissue adhesives.
Alex Ross   +8 more
wiley   +1 more source

Fyn Regulates Binding Partners of Cyclic-AMP Dependent Protein Kinase A

open access: yesProteomes, 2018
The cAMP-dependent protein kinase A (PKA) is a serine/threonine kinase involved in many fundamental cellular processes, including migration and proliferation.
Anna M. Schmoker   +6 more
doaj   +1 more source

A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids

open access: yesAdvanced Healthcare Materials, EarlyView.
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova   +7 more
wiley   +1 more source

GABAC-Receptor Stimulation Activates cAMP-Dependent Protein Kinase via A-Kinase Anchoring Protein 220

open access: yesJournal of Pharmacological Sciences, 2008
In our previous study, anti-apoptotic effects of GABAC-receptor stimulation was suppressed by inhibitors of cAMP-dependent protein kinase (PKA), implying GABACreceptor–mediated PKA activation. The present study showed that GABAC-receptor stimulation with
Li Yang   +4 more
doaj   +1 more source

Protein Kinase Inhibitor Peptide as a Tool to Specifically Inhibit Protein Kinase A

open access: yesFrontiers in Physiology, 2020
The protein kinase enzyme family plays a pivotal role in almost every aspect of cellular function, including cellular metabolism, division, proliferation, transcription, movement, and survival.
Chong Liu   +4 more
doaj   +1 more source

From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function

open access: yesAdvanced Healthcare Materials, EarlyView.
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini   +2 more
wiley   +1 more source

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