Results 81 to 90 of about 194,517 (249)
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
Spectrophotometric Determination of Acidity Constants of Thiamine in Water, Water-Triton X-100 Micellar Media Solutions [PDF]
In this work the acidity constants of Thiamine in water and water-Triton X-100 micelle media solutions, at 25 °C, have been determined spectrophotometrically.
Mohammad Goodarzi, Tahmineh Goodarzi
doaj
A, Model network pathway of PKA dynamics. R and C represent the regulatory subunit and catalytic subunit of PKA, respectively, where the amount of PKA activity is considered identical to C activity.
Carole A. Farah (336422) +3 more
core +1 more source
Schematic illustration of development of experimental datasets and algorithm models, screening and preparation of the scaffolds and their applications in vivo. ABSTRACT Bone defects require materials with osteogenic, neurogenic, and angiogenic activity, yet designing such materials within high‐dimensional compositional spaces remains challenging. Here,
Kunlu Lin +9 more
wiley +1 more source
KITLV- Bunga Rampai Temu Budaya Nusantara PKA-3
PKA = Pekan Kebudayaan Aceh Met Lit ...
Ismuha
core
This work presents a computational–experimental strategy to engineer material‐binding peptides toward polymer specificity. Molecular dynamics simulations identified residues driving polystyrene binding, enabling targeted substitutions that greatly reduced polystyrene affinity while preserving PET binding.
Julian Luka +3 more
wiley +1 more source
Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao +5 more
wiley +1 more source
Fyn Regulates Binding Partners of Cyclic-AMP Dependent Protein Kinase A
The cAMP-dependent protein kinase A (PKA) is a serine/threonine kinase involved in many fundamental cellular processes, including migration and proliferation.
Anna M. Schmoker +6 more
doaj +1 more source
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem +24 more
wiley +1 more source

