Results 91 to 100 of about 191,349 (283)

Determination of Acid Dissociation Constants of Some 2-(3H) –Benzoxazolone Derivatives by UV–Vis Spectrophotometry [PDF]

Iranian Journal of Chemistry & Chemical Engineering
The acid dissociation constant values of some 2-(3H)-benzoxazolone derivatives were determined in buffered solutions by using the UV-Vis spectrophotometric method.
Semra Altunterim Erkan, Hayati Celik, Banu Kesanlı   +2 more
doaj   +1 more source

The Protein Kinase A-Dependent Phosphoproteome of the Human Pathogen Aspergillus fumigatus Reveals Diverse Virulence-Associated Kinase Targets

mBio, 2020
Protein kinase A (PKA) signaling plays a critical role in the growth and development of all eukaryotic microbes. However, few direct targets have been characterized in any organism.
E. Keats Shwab, Praveen R. Juvvadi, Greg Waitt, Shareef Shaheen, John Allen, Erik J. Soderblom, Benjamin G. Bobay, Yohannes G. Asfaw, M. Arthur Moseley, William J. Steinbach   +9 more
doaj   +1 more source

TOCP treatment reduces PKA activity.

, 2014
A. Flies treated with 16 mg/ml TOCP reveal a significant reduction in PKA activity in head extracts whereas flies treated with Paraoxon (PO; 0.2 mg/ml) show no change in PKA activity. B.
Jill S. Wentzell (308546), Doris Kretzschmar (308547), Marlène Cassar (523925)   +2 more
core   +1 more source

Ti‐Doping Activates Adjacent Zr Sites in Bimetallic MOFs for Cooperative Phospholipid Removals in Human Biomonitoring

Advanced Science, EarlyView.
Ti‐doped Zr/Ti bimetallic MOFs activate neighboring Zr sites to selectively capture phospholipids from serum through cooperative interactions. In nontargeted screening, the material minimizes matrix interference, expands detectable feature coverage, and enables broad recovery of diverse chemical hazards, providing a powerful cleanup strategy for LC ...
Yanmin Liang, Hongyue Ma, Feier Bai, Jing Zhang, Yan Qi, Bing Shao   +5 more
wiley   +1 more source

Comparison of productive and carcass traits and economic value of lines selected for different criteria, slaughtered at similar weights

World Rabbit Science, 2016
The aim of the experiment was to compare 3 genetic groups, slaughtered at similar weights, to examine their productive and carcass traits and economic value.
K. Szendrő, ZS. Szendrő, ZS. Gerencsér, I. Radnai, P. Horn, ZS. Matics   +5 more
doaj   +1 more source

The tails of PKA

, 2022
Protein kinase A (PKA) is a holoenzyme consisting of a regulatory (R)-subunit dimer and two catalytic (C)-subunits. There are two major families of C-subunits, Cα and Cβ, and four functionally nonredundant R-subunits (RIα, RIβ, RIIα, RIIβ). In addition to binding to and being regulated by the R-subunits, the C-subunits are regulated by two tail regions
Taylor, Susan S, Søberg, Kristoffer, Kobori, Evan, Wu, Jian, Pautz, Sabine, Herberg, Friedrich W, Skålhegg, Bjørn Steen   +6 more
openaire   +2 more sources

Reciprocal regulation of PKA and rac signaling [PDF]

, 2013
Activated G protein-coupled receptors (GPCRs) and receptor tyrosine kinases relay extracellular signals through spatial and temporal controlled kinase and GTPase entities.
Stefan, E., Bachmann, V.A., Riml, A., Baillie, G.S., Liedl, K.R., Valovka, T., Huber, R.G.   +6 more
core   +1 more source

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

Advanced Science, EarlyView.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae, Jisun Lee, Jae‐Hun Ahn, Hosam Choi, Huijeong Choi, Jungmin Kim, Minho Kang, Ho Rim Oh, So Hyun Park, Eun Young Oh, Sanghyuk Jeon, Yeeun Lee, Yu‐Sun Lee, Na‐Young Lee, Hee‐Jin Bae, Jina Kwak, Jooil Kim, Nakyung Lee, Beomsun Kang, Ji‐Hye Kim, Eunsaem Song, Daesub Song, Hyunho Yoon, Sang‐Myeong Lee, Hyewon Youn, Kiyoun Lee, Byeong‐Cheol Kang, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Spectrophotometric Determination of Acidity Constants of Thiamine in Water, Water-Triton X-100 Micellar Media Solutions [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2008
In this work the acidity constants of Thiamine in water and water-Triton X-100 micelle media solutions, at 25 °C, have been determined spectrophotometrically.
Mohammad Goodarzi, Tahmineh Goodarzi
doaj  

Liberated PKA Catalytic Subunits Associate with the Membrane via Myristoylation to Preferentially Phosphorylate Membrane Substrates

Cell Reports, 2017
Summary: Protein kinase A (PKA) has diverse functions in neurons. At rest, the subcellular localization of PKA is controlled by A-kinase anchoring proteins (AKAPs). However, the dynamics of PKA upon activation remain poorly understood.
Shane E. Tillo, Wei-Hong Xiong, Maho Takahashi, Sheng Miao, Adriana L. Andrade, Dale A. Fortin, Guang Yang, Maozhen Qin, Barbara F. Smoody, Philip J.S. Stork, Haining Zhong   +10 more
doaj   +1 more source