Results 91 to 100 of about 194,517 (249)

GABAC-Receptor Stimulation Activates cAMP-Dependent Protein Kinase via A-Kinase Anchoring Protein 220

Journal of Pharmacological Sciences, 2008
In our previous study, anti-apoptotic effects of GABAC-receptor stimulation was suppressed by inhibitors of cAMP-dependent protein kinase (PKA), implying GABACreceptor–mediated PKA activation. The present study showed that GABAC-receptor stimulation with
Li Yang, Yasuhisa Nakayama, Naoki Hattori, Bing Liu, Chiyoko Inagaki   +4 more
doaj   +1 more source

Hydrogen‐Bond Enabled Phosphite Based Intrinsic Flame‐Retardant Solid‐Solid Phase Change Materials Using Catalyst/Solvent‐Free Multi‐Component Reaction for Battery Thermal Management

Advanced Science, EarlyView.
The phosphite group endows intrinsic flame retardancy, while the P = O bond enhances intermolecular interactions to realize solid‐solid phase transition. Battery thermal management tests show the materials extend the safe working time of lithium‐ion batteries by 200%. Cone calorimeter tests indicate a 14s delay in ignition time, and reductions of 37.6%,
Changhui Liu, Guangyuan Liang, Yuanzheng Liu, Jiantang Gao, Zeyang Li, Lin Huang, Jiateng Zhao, Junbing Xiao, Xiaoxing Zhong, Jun (Joelle) Wang   +9 more
wiley   +1 more source

PKA-mediated inhibition of a novel K+ channel underlies the slow after-hyperpolarization in enteric AH neurons.

, 2003
PKA-mediated inhibition of a novel K+ channel underlies the slow after-hyperpolarization in enteric AH ...
John R Harvey (19455376), John Furness (13070439), Fivos Vogalis (19448368)   +2 more
core  

Sonic-hedgehog-mediated proliferation requires the localization of PKA to the cilium base

, 2010
Cerebellar granular neuronal precursors (CGNPs) proliferate in response to the mitogenic activity of Sonic hedgehog (Shh), and this proliferation is negatively regulated by activation of cAMP-dependent protein kinase (PKA).
Álvarez-Rodríguez, Rubén, Pons, Sebastián, Barzi Diéguez, Mercedes, Menendez, Anghara, Berenguer, Jordi, Anghara Menendez, Ruben Alvarez-Rodriguez, Sebastian Pons, Jordi Berenguer, Mercedes Barzi   +9 more
core   +1 more source

Bioinspired Porphyrin‐Based Catalysts From Temporospatial Confined Frameworks for Ultrafast Removal of Sulfaclozine

Advanced Science, EarlyView.
We report the rational design of artificial photocatalysts with asymmetrically coordinated dual‐metal centers and a tailored microenvironment, broadly applicable strategy is established for the synthesis of multivariate zirconium‐based metal–organic frameworks, offering a platform for precisely tuning active‐site configurations to optimize ...
Yuxin Lu, Yu‐Hang Li, Zhiyi Sun, Fanke Tong, Zelin Li, Sheng Wang, Shangkun Pei, Yi Li, Xiyan Xu, Chong‐Chen Wang, Bo Wang, Xiang Li   +11 more
wiley   +1 more source

Charakterisierung kleiner Moleküle zur Hemmung von AKAP-PKA-Interaktionen

, 2009
A-kinase anchoring proteins (AKAP) tether the cAMP-dependent protein kinase (PKA) to subcellular structures in proximity to its substrates, providing the basis for compartmentalised cAMP signalling.
Christian, Frank
core   +1 more source

Polyelectrolyte Multilayer: Caged PTFE Particles in Water for Continuous, Sonochemical H2O2 Synthesis

Advanced Science, EarlyView.
A yolk–shell PTFE‐based composite (YSP) enables tunable, robust hydrophobic–water interfaces for efficient, on‐demand sonocatalytic H2O2 generation and pollutant degradation. ABSTRACT The use of polytetrafluoroethylene (PTFE) particles to promote sonochemical H2O2 production has attracted growing interest, as cavitation bubbles formed at or near their ...
Rong Wang, Bo Wang, Tengyue Fu, Yue Yang, Chongling Cheng, Zhenhui Qi, Dayang Wang   +6 more
wiley   +1 more source

14-3-3 adaptors interact with PKA and Ung.

, 2013
(a) Schematics of the principle of the BiFC assays to analyze interaction of 14-3-3 (HA–14-3-3–EYFP155–238) with PKA-Cα (Flag–PKA-Cα–EYFP1–154), PKA-RIα (Flag–PKA-RIα–EYFP1–154), RPA1 (Flag–RPA1–EYFP1–154) or Ung (Flag–Ung–EYFP1–154).
Tonika Lam (489334), Lisa M. Thomas (489335), Clayton A. White (489336), Zhenming Xu (489339), Guideng Li (489337), Egest J. Pone (489338), Paolo Casali (489340)   +6 more
core   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

Reciprocal regulation of PKA and rac signaling [PDF]

, 2013
Activated G protein-coupled receptors (GPCRs) and receptor tyrosine kinases relay extracellular signals through spatial and temporal controlled kinase and GTPase entities.
Stefan, E., Bachmann, V.A., Riml, A., Baillie, G.S., Liedl, K.R., Valovka, T., Huber, R.G.   +6 more
core   +1 more source