Results 51 to 60 of about 322,068 (275)

Photocatalytic Versus Stoichiometric Hydrogen Generation Using Mesoporous Silicon Catalysts: The Complex Role of Sacrificial Reagents

open access: yesAdvanced Functional Materials, EarlyView.
This study highlights the importance of accounting for stoichiometric hydrogen produced when utilizing Si photocatalysts. The stoichiometric contribution is sacrificial reagent dependent and decreases with increasing sterics around the catalyst surface.
Sarrah H. Putwa   +4 more
wiley   +1 more source

Performance Model of Multichannel Deflection-Routed All-Optical Networks With Packet Injection Control [PDF]

open access: yes, 2014
Deflection routing is a feasible approach to resolve the output contention problem in packet-switched networks when buffering of packets is not practical.
Li, CY, Li, VOK, Wai, PKA
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz   +3 more
wiley   +1 more source

Ligustroside derived from Ligustrum japonicum inhibits melanogenesis via blocking the MAPK and PKA/CREB signaling pathways

open access: yesAsian Pacific Journal of Tropical Biomedicine
Objective: To investigate the anti-melanogenic potential of ligustroside isolated from Ligustrum japonicum. Methods: The cytotoxicity of ligustroside was tested via MTT assay.
Xian-Rong Zhou   +4 more
doaj   +1 more source

Theoretical investigation of cyclooxygenase inhibition property of several non-steroidal anti-inflammatory drugs by density functional theory calculations and molecular docking studies [PDF]

open access: yesTrends in Pharmaceutical Sciences, 2015
Understanding the geometry, electronic properties of non-steroidal anti-inflammatory drugs (NSAIDs) and the nature of their interactions with human cyclooxygenase-2 (COX-2) is important in development and design of novel NSAIDs.
Atena Najdian   +4 more
doaj  

Functionally distinct and selectively phosphorylated GPCR subpopulations co-exist in a single cell. [PDF]

open access: yes, 2018
G protein-coupled receptors (GPCRs) transduce pleiotropic intracellular signals in a broad range of physiological responses and disease states. Activated GPCRs can undergo agonist-induced phosphorylation by G protein receptor kinases (GRKs) and second ...
Chowdhury, Dhrubajyoti   +8 more
core   +3 more sources

Signaling diversity of PKA achieved via a Ca2+-cAMP-PKA oscillatory circuit [PDF]

open access: yesNature Chemical Biology, 2010
Many protein kinases are key nodal signaling molecules that regulate a wide range of cellular functions. These functions may require complex spatiotemporal regulation of kinase activities. Here, we show that protein kinase A (PKA), Ca(2+) and cyclic AMP (cAMP) oscillate in sync in insulin-secreting MIN6 beta cells, forming a highly integrated ...
Ni, Qiang   +6 more
openaire   +2 more sources

Tailoring the Properties of Functional Materials With N‐Oxides

open access: yesAdvanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich   +5 more
wiley   +1 more source

Theoretical study on the protonation of AZA-aromatics [PDF]

open access: yes, 1975
The protonation of azanaphthalenes and azabenzenes has been studied theoretically using CNDO/2 wavefunctions and perturbation theory in order to examine the correlation between pKa values and quantum-mechanical ...
Meer, Douwe van der   +1 more
core   +2 more sources

Biphasic pKa Values

open access: yesCroatica Chemica Acta, 2018
A novel approach – termed here as biphasic pKa values – is presented for quantifying the acidity/basicity of lipophilic compounds embedded in water-immiscible media (membranes or solutions) at equilibrium with aqueous solution. In this approach the hydrogen ion activity is determined in the aqueous phase, while the concentration ratio of protonated and
Selberg, Sigrid   +2 more
openaire   +2 more sources

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