Results 121 to 130 of about 16,547 (202)
PKM2: The Thread Linking Energy Metabolism Reprogramming with Epigenetics in Cancer [PDF]
, 2014 Ling Chen +5 more
openalex +1 more source
Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.Vesicle‐associated membrane protein 7 (VAMP7) plays a pivotal role in HPV16‐driven cervical cancer by regulating autophagy, promoting tumour cell survival, immune evasion and lesion progression. These findings highlight VAMP7 as a potential therapeutic target, offering new opportunities for early intervention and treatment of cervical cancer.
Weijuan Xin +9 more
wiley +1 more source
European Journal of Immunology, Volume 56, Issue 1, January 2026.The increased lactate secretion by B cells from people with obesity and aging is a stimulus for pathogenic autoimmune anti‐dsDNA antibodies. The effects of lactate are mediated by phosphorylated signal transducer and activator of transcription 3 (p‐STAT3) and inhibited by a neutralizing antibody that blocks the lactate transporter SLC5A12, responsible ...
Maria Romero +7 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 1, January 2026.ABSTRACT Ferroptosis resistance is a key player in cervical cancer (CC) development. Hypoxia is a negative factor affecting CC treatment by inducing ferroptosis resistance. Our study aimed to investigate the detailed mechanisms of hypoxia‐induced ferroptosis resistance in CC cells.
Yan Gao, Ting Zou
wiley +1 more source
MedComm, Volume 7, Issue 1, January 2026.We identified first time a critical m6A modification of circIST1 on miR‐140‐3p/miR‐182‐HIF1α regulatory network involved in the HCC progression and tumor glycolysis, gaining mechanistic insights into the function of circRNAs in HCC progression. ABSTRACT The involvement of circular RNAs (circRNAs) have been well‐documented in various cancers, including ...
Yangyang Zhan +12 more
wiley +1 more source
PKM2-mediated STAT3 phosphorylation promotes acute liver failure via regulating NLRP3-dependent pyroptosis [PDF]
Songman Yu +8 more
openalex +1 more source
Mediation of PKM2-dependent glycolytic and non-glycolytic pathways by ENO2 in head and neck cancer development [PDF]
, 2023 Lixia Gao +8 more
openalex +1 more source
The FASEB Journal, Volume 39, Issue 24, 31 December 2025.We investigated two models of mitochondrial dysfunction in podocytes, using two cell culture models: podocytes isolated from mice with Oma1 deletion (Oma1del) and mouse podocytes modified with an inducible knockdown of PHB2 (Phb2kd). OMA1 deficiency induced a glycolytic shift, enhanced glutamine anaplerosis, and sustained energy homeostasis after ...
Cem Özel +13 more
wiley +1 more source