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Changes in PKM2 Associate with Prostate Cancer Progression

Cancer Investigation, 2014
Pyruvate kinase M2 (PKM2) is essential for aerobic glycolysis, the dominant metabolic pathway utilized by cancer cells. To determine the association of PKM2 with prostate cancer (PC), we examined 29 primary PC and three lymph node metastatic tumors; elevation of PKM2 was observed in Gleason 8-10 tumors compared to Gleason 6-7 carcinomas.
Nicholas, Wong   +5 more
openaire   +2 more sources

PKM2 is a Novel Osteoporosis-Associated Protein in Chinese

Endocrine Research
                       Purpose:Osteoporosis is characterized by low bone mineral density (BMD) and high risk of osteoporotic fracture (OF). Peripheral blood monocytes (PBM) can differentiate into osteoclasts to resorb bone. This study was to identify PBM-expressed proteins significant for osteoporosis in Chinese Han elderly population (>65 years), and ...
Qing Xu   +7 more
openaire   +2 more sources

PKM2 as a protein kinase

Nature Reviews Molecular Cell Biology, 2012
openaire   +1 more source

PKM2

2018
openaire   +1 more source

PKM2: A novel helmsman of lipid metabolism

Cellular Signalling
Zhijun Liu, Yifei Le, Dezhao Lu
openaire   +1 more source

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