Results 111 to 120 of about 39,920 (262)

Herramientas moleculares para la detección de sistemas biosintéticos PKS-I, PKS-II Y NRPS en actinomicetos

open access: yes, 2003
Tesis doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Ciencias, Departamento de Biología Molecular, Fecha de lectura 26-11-2003In the last decades natural products screening programs have devoted an enormous effort to discover ...
Ayuso Sacido, Angel
core   +1 more source

Atypical Condensation Domains Guide Discovery and Illuminate Biosynthesis of Myxoglucamides Featuring Vinyl‐Substituted, α‐Oxidized γ‐Amino Acids

open access: yesAngewandte Chemie, Volume 138, Issue 41, 5 October 2026.
Genome mining of atypical condensation (C) domains leads to the discovery of myxoglucamides, glycolipopeptides featuring an unprecedented vinyl‐substituted, α‐oxidized γ‐amino acid. Biosynthetic studies reveal a discrete C‐domain‐like O‐acyltransferase, a β‐hydroxylation‐dependent chain‐extension checkpoint, and an unusual pathway for γ‐amino acid ...
Tingting Wang   +10 more
wiley   +2 more sources

Reconstruction of deep and perforating corneal defects in dogs—A review (Part I/III): Autogenous ocular tissues, donor tissues, and corneal clarity scoring

open access: yesVeterinary Ophthalmology, Volume 28, Issue 2, Page 519-531, March 2025.
Abstract Corneal reconstruction is a key part of veterinary ophthalmic practice and numerous reconstructive techniques have been described for use in small animals in the peer‐reviewed veterinary literature written in English. Despite the evidence accrued over the last six decades in over 40 clinical articles and numerous other publications on ocular ...
Rick F. Sanchez   +2 more
wiley   +1 more source

Numerical and Experimental Evaluation of a Simplified Lateral Spring Formulation for Rocking Structures

open access: yesEarthquake Engineering &Structural Dynamics, Volume 55, Issue 14, Page 3540-3560, November 2026.
ABSTRACT Rocking podium isolation systems have gained significant research interest as a method of limiting seismic demands on superstructures and eliminating residual post‐earthquake drifts through self‐centring behaviour. However, while numerous models of varying complexity, including analytical, phenomenological, and physical formulations, have been
Marawan Zaki   +2 more
wiley   +1 more source

Intratumoural pks+ Escherichia coli is associated with risk of metachronous colorectal cancer and adenoma development in people with Lynch syndromeResearch in context

open access: yesEBioMedicine
Summary: Background: The adverse gut microbiome may underlie the variability in risks of colorectal cancer (CRC) and metachronous CRC in people with Lynch syndrome (LS). The role of pks+/− Escherichia coli (pks+/− E.
Yen Lin Chu   +21 more
doaj   +1 more source

Incidence Trends of Early‐Onset Colorectal Cancer in Germany: A Registry‐Based Study From 2003 to 2023

open access: yesInternational Journal of Cancer, Volume 159, Issue 9, Page 2207-2218, 1 November 2026.
The evidence on the rising incidence of colorectal cancer among adults below 50 years of age largely stems from the United States. Using high‐quality cancer registry data for the 2003–2023 period in Germany, this study found a moderate increase of early‐onset colorectal cancer incidence that was limited to those aged 20–39 years and more pronounced ...
Sven Voigtländer   +20 more
wiley   +1 more source

KONSISTENSI PKS DALAM MEMPERJUANGKAN HARKAT DAN MARTABAT PEREMPUAN (Studi Pada: DPD PKS Lampung Utara) [PDF]

open access: yes, 2018
Skripsi ini membahas tentang konsistensi PKS dalam memperjuangkan harkat dan martabat perempuan. Fenomena politik perempuan di Indonesia telah lama menjadi perdebatan yang belum kunjung usai.
Mahtuti, Tri
core   +1 more source

First‐In‐Human Study of Mirogabalin (BM2216) Sustained‐Release Tablets: Safety, Tolerability, Pharmacokinetics, Food Effect and Dose Proportionality With Comparison to Mirogabalin Besylate in Healthy Participants

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10795-10813, November 2026.
ABSTRACT Aim To characterise the pharmacokinetics (PKs) and safety of BM2216 sustained‐release (SR) tablets after single‐dose oral administration under fasted/fed conditions in healthy participants, assess the effect of food and dose proportionality, and compare the single and multiple‐dose PK of BM2216 SR tablets with mirogabalin besylate tablets to ...
Peiyang Song   +6 more
wiley   +1 more source

Czy istnieje potrzeba zmiany nazwy PKS? [PDF]

open access: yes, 2013
W wyniku prywatyzacji wiele przedsiębiorstw Państwowej Komunikacji Samochodowej znika z mapy kraju. Jedne zostają kupione przez większe firmy transportowe inne przejmowane są przez samorządy gminne, powiatowe i wojewódzkie.
Abramowicz, A.
core  

Depression Beyond the 6‐Month Postpartum Period: A Mixed‐Method Study Among Women in Nepal

open access: yesJournal of Advanced Nursing, Volume 82, Issue 11, Page 10029-10042, November 2026.
ABSTRACT Aim This study aimed to comprehensively examine social and clinical factors contributing to postpartum depression among women in Nepal and identify their perspectives/experiences regarding postpartum mental health. Design and Methods The explanatory sequential mixed‐method study was conducted in two phases. In the quantitative phase, data were
Sangita Pudasainee‐Kapri   +7 more
wiley   +1 more source

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