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Genomic characterization of Escherichia coli harbor a polyketide synthase ( pks ) island associated with colorectal cancer (CRC) development

Abstract The E. coli strain harboring the polyketide synthase ( Pks) island encodes the genotoxin colibactin, a secondary metabolite reported to have severe implications for human health and for the progression of colorectal ...
Chao, Lv   +11 more
openaire   +2 more sources

Insights into the acquisition of the pks island and production of colibactin in the Escherichia coli population

Microbial Genomics, 2021
Frédéric Auvray   +2 more
exaly  

Expression Variations of MBF-1, PKS and psbA Genes in Umbilicaria decussata Collected from Horseshoe Island (Antarctic Peninsula) and the Southern Coast of Turkiye

Antarktika likenleri, çevresel değişimin göstergesi olarak bilimsel araştırmalara katkıda bulunarak bilim adamlarının iklim değişikliğinin ve insan faaliyetinin etkilerini izlemesine yardımcı olur. Liken türlerinin bu farklı habitatlara ve ekstrem koşullara adaptasyonu, genetik arka planlarındaki genlerin hızlı ekspresyonundan kaynaklanmaktadır.
Bölükbaşı, Ekrem   +1 more
openaire   +1 more source

pks+ Escherichia coli more prevalent in benign than malignant colorectal tumors

Molecular Biology Reports, 2021
Kin Israel Notarte   +2 more
exaly  

Mo1603 The E. coli Genotoxic Island Pks Promotes Colorectal Cancer (CRC) Without Impacting Intestinal Inflammation

Gastroenterology, 2012
Janelle C. Arthur   +10 more
openaire   +1 more source

Isolation of a Metabolite from the pks Island Provides Insights into Colibactin Biosynthesis and Activity

Organic Letters, 2015
Carolyn A Brotherton   +2 more
exaly  

Molecular Epidemiology and Phylogenetic Distribution of the Escherichia coli pks Genomic Island

Journal of Clinical Microbiology, 2008
James R Johnson   +2 more
exaly  

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