Results 81 to 90 of about 2,539 (164)

[Presence of genes of genotoxin associated with pks pathogenicity island in Escherichia coli M-17 probiotic strain].

Zhurnal mikrobiologii, epidemiologii i immunobiologii, 2012
Study the presence of genetic determinants of pks pathogenicity island containing clb (colibactin) genes in bacteria of the E. coli M-17 production strain by using PCR.E. coli M-17 cultures isolated from biopreparations bificol (Microgen) and colibacterin (Biomed) and control strain obtained from Tarasevich State Institute on Standardization and ...
V M, Bondarenko, S V, Fialkina
openaire   +1 more source

Prevalence and Molecular Characteristics of Klebsiella pneumoniae Harboring the Pks Island from Cancer Patients in China

Infection and Drug Resistance
Qun Wang,1 Xingwei Wang,2 Zhenghua Xie,1 Jiuxin Qu,2 Yongping Lin,1 Jing Hu,3 Liqiang Li,2 Li Zhang1 1National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and ...
Wang Q, Wang X, Xie Z, Qu J, Lin Y, Hu J, Li L, Zhang L   +7 more
doaj  

Prevalence and pathologic effects of colibactin and cytotoxic necrotizing factor-1 (Cnf 1) in Escherichia coli: experimental and bioinformatics analyses

Gut Pathogens, 2019
Background The colibactin and cytotoxic necrotizing factor 1 (Cnf 1) are toxins with cell cycle modulating effects that contribute to tumorgenesis and hyperproliferation.
Radwa N. Morgan, Sarra E. Saleh, Hala A. Farrag, Mohammad M. Aboulwafa   +3 more
doaj   +1 more source

L-serine promotes pro-carcinogenic effects of colibactin-producing E. coli

Gut Microbes
Colonic tissues are abnormally colonized by colibactin-producing Escherichia coli (CoPEC) in colorectal cancer (CRC) patients. CoPECs have been shown to promote colorectal carcinogenesis in several pre-clinical CRC mouse models.
Amandine Devaux, Romain Villéger, Gwenaëlle Roche, Binta Diémé, Michael Rodrigues, Charline Juban, Marie Lagrée, Nicolas Venisse, Cyril Jousse, Nicolas Barnich, Mathilde Bonnet   +10 more
doaj   +1 more source

Colibactin contributes to the hypervirulence of pks(+) K1 CC23 Klebsiella pneumoniae in mouse meningitis infections

, 2017
[[abstract]]Klebsiella pneumoniae is the most common pathogen of community-acquired meningitis in Taiwan. However, the lack of a physiologically relevant meningitis model for K. pneumoniae has impeded research into its pathogenesis mechanism.
Lu, MC;Chen, YT;Chiang, MK;Wang, YC;Hsiao, PY;Huang, YJ;Lin, CT;Cheng, CC;Liang, CL;Lai, YC
core   +1 more source

Role of the pks/clb island in EcN antibacterial activity on LF82.

, 2019
(A) Serial dilutions (ten-fold) of 24-hour co-cultures of E. coli LF82 (rifampicin resistant) with wild-type (WT) E. coli strain Nissle 1917 (EcN) or the mutant for the colibactin maturing peptidase ClbP, spotted (10 μL) on LB plate containing rifampicin
Priscilla Branchu (507991), Jean-Philippe Nougayrède (45294), Eric Oswald (45298), Michèle Boury (432964), Damien Dubois (282339), Clémence Massip (7419182), Nadège Bossuet-Greif (7460966), Déborah Gaillard (7419191), Camille V. Chagneau (7419188), Thomas Sécher (7419194), Patricia Martin (41047)   +10 more
core   +1 more source

L'ilot génomique pks chez Escherichia coli : structure-fonction de la protéine ClbP et études épidémiologiques

, 2011
The pks genomic island of Escherichia coli and other Enterobacteriaceae encodes polyketide andnonribosomal peptide synthases that build a putative hybrid PK-NRP compound.
Dubois, Damien
core   +1 more source

Intratumoral presence of the genotoxic gut bacteria pks+ E. coli, Enterotoxigenic Bacteroides fragilis, and Fusobacterium nucleatum and their association with clinicopathological and molecular features of colorectal cancer

Background: This study aimed to investigate clinicopathological and molecular tumour features associated with intratumoral pks+ Escherichia coli (pks+E.coli+), pks+E.coli- (non-E.coli bacteria harbouring the pks island), Enterotoxigenic Bacteroides ...
Georgeson, P, Walker, R, Southey, MC, Buchanan, DD, Winship, IM, Hopper, JL, Joseland, S, Win, AK, Toner, J, Clendenning, M, Ingle, DJ, Sherry, NL, Chu, YL, Diepenhorst, N, Meyers, AL, Lynch, BM, Mahmood, K, Como, J, Preston, SG, Jenkins, MA, Metz, A, Joo, JE, Milne, RL, Macrae, FA, Rosty, C   +24 more
core   +1 more source

What makes Xanthomonas albilineans unique amongst xanthomonads?

Frontiers in Plant Science, 2015
Xanthomonas albilineans causes leaf scald, a lethal disease of sugarcane. Compared to other species of Xanthomonas, X. albilineans exhibits distinctive pathogenic mechanisms, ecology and taxonomy.
Isabelle ePieretti, Alexander ePesic, Daniel ePetras, Monique eRoyer, Roderich D Süssmuth, Stéphane eCociancich   +5 more
doaj   +1 more source

Model for the co-evolution of the pks and high pathogenicity islands in E. coli.

, 2013
Left. Phylogenetic relationships amongst the E. coli reference strains (ECOR, [3], [52]). The phylogeny was based on MLST of back-bone genes [3], [43]. Ent locus positive strains are indicated in blue, HPI island positive strains are indicated in green ...
Eric Oswald (45298), Christian Chalut (111598), Patricia Martin (41047), Jean-Philippe Nougayrède (45294), Christophe Garcie (432962), Sören Schubert (172752), Michèle Boury (432964), Marc Audebert (386065), Giuseppe Magistro (268305), Delphine Payros (432963), Maïwenn Olier (432965), Marie Penary (20069), Ingrid Marcq (432961)   +12 more
core   +1 more source