Results 71 to 80 of about 2,539 (164)
Investigation of horizontal gene transfer of pathogenicity islands in Escherichia coli using next-generation sequencing. [PDF]
PLoS ONE, 2017 Horizontal gene transfer (HGT) contributes to the evolution of bacteria. All extraintestinal pathogenic Escherichia coli (ExPEC) harbour pathogenicity islands (PAIs), however relatively little is known about the acquisition of these PAIs.
Maxim Messerer +2 more
doaj +1 more source
Environmental Microbiology, Volume 28, Issue 5, May 2026.Abyssal sediments were assessed for taxonomic diversity and polyketide biosynthetic potential and compared to metagenomic and metabolomic assessments of the same sediments. Biodiversity differences were documented across biogeochemical regimes with the results providing baseline awareness of what might be lost should deep‐sea microbiomes be disrupted ...
Hans W. Singh +7 more
wiley +1 more source
APMIS, Volume 134, Issue 5, May 2026.ABSTRACT Familial adenomatous polyposis (FAP) is a hereditary condition marked by the growth of hundreds to thousands of adenomatous polyps in the colon and rectum, significantly elevating the risk of colorectal cancer (CRC) if left untreated. Caused by pathogenic variants in the APC gene, FAP is typically identified in adolescence, often leading to ...
John Gásdal Karstensen
wiley +1 more source
Cancer Science, Volume 117, Issue 5, Page 1223-1234, May 2026.Shared risk factors, clinical features, and tumor characteristics across multiple early‐onset cancer types are shown in this Graphical Abstract. Integrative approaches combining molecular pathology, oncology, and population sciences offer opportunities to clarify underlying mechanisms and help us develop preventive strategies for early‐onset cancers ...
Nobuhiro Nakazawa +17 more
wiley +1 more source
مجلة بغداد للعلومColibactin is a genotoxin produced by Enterobacteriaceae via a polyketide synthase (pks) island cluster. There is less knowledge regarding the distribution of colibactin genes in E.
Rukiya Saad Jassam, Husam Sabah Auhim
doaj +1 more source
Frontiers in Genetics, 2019 The gut microbiota has been implicated in a number of normal and disease biological processes. Recent studies have identified a subset of gut bacterial genes as potentially involved in inflammatory processes.
Ramón Gómez-Moreno +8 more
doaj +1 more source
Bacterial Infections Role in Gynecological Cancers Development: Narrative Review
Cancer Reports, Volume 9, Issue 4, April 2026.ABSTRACT Background Gynecological cancers are among the most common cancers in women that affect female reproductive organs. The most common gynecological cancers are ovarian, cervical, uterine/endometrial, vaginal, and vulvar cancer. Women's reproductive organs have a dynamic and relative microbial balance.
Robab Azargun +7 more
wiley +1 more source
People and Nature, Volume 8, Issue 4, Page 854-870, April 2026.Abstract Ecosystem services are rapidly degrading under anthropogenic pressure. Therefore, it is increasingly important to understand how ecosystem services flow, particularly at local scales, where people directly rely on nature for their livelihoods and well‐being. Many ecosystem services are underpinned by ecological (e.g.
Anna Stanworth +8 more
wiley +1 more source
, 2017 Some Escherichia coli strains of phylogroup B2 harbor a (pks) pathogenicity island that encodes a polyketide-peptide genotoxin called colibactin. It causes DNA double-strand breaks and megalocytosis in eukaryotic cellsand it may contribute to cancer ...
Mauro Nicoletti +23 more
core +1 more source
The Polyamine Spermidine Modulates the Production of the Bacterial Genotoxin Colibactin
mSphere, 2019 Colibactin is a polyketide/nonribosomal peptide produced by Escherichia coli strains that harbor the pks island. This toxin induces DNA double-strand breaks and DNA interstrand cross-links in infected eukaryotic cells.
Camille V. Chagneau +8 more
doaj +1 more source