Results 31 to 40 of about 9,473,872 (308)

Overwriting the past with supervised plasticity

eLife, 2022
Triggered activity bursts in place cells can increase and decrease the strength of some inputs.
Xingyun Wang, Richard Naud
doaj   +1 more source

Place Cells, Grid Cells, Attractors, and Remapping [PDF]

Neural Plasticity, 2011
Place and grid cells are thought to use a mixture of external sensory information and internal attractor dynamics to organize their activity. Attractor dynamics may explain both why neurons react coherently following sufficiently large changes to the environment (discrete attractors) and how firing patterns move smoothly from one representation to the ...
openaire   +4 more sources

Experience-Dependent Egr1 Expression in the Hippocampus of Japanese Quail

Frontiers in Psychology, 2022
The hippocampal formation (HF) is a structure critical to navigation and many forms of memory. In mammals, the firing of place cells is widely regarded as the fundamental unit of HF information processing.
Chelsey C. Damphousse, Noam Miller, Diano F. Marrone   +2 more
doaj   +1 more source

Mesenchymal cell invasion requires cooperative regulation of persistent microtubule growth by SLAIN2 and CLASP1 [PDF]

, 2016
Microtubules regulate signaling, trafficking, and cell mechanics, but the respective contribution of these functions to cell morphogenesis and migration in 3D matrices is unclear.
Noordstra, Ivar, Katrukha, Eugene A., Derksen, Patrick W. B., Katrukha, Eugene A, van Amersfoort, Miranda, Ter Hoeve, Natalie D, Celbiologie, Bouchet, Benjamin P, Derksen, Patrick W B, Dogterom, Marileen, Ammon, York-Christoph, Bouchet, Benjamin P., Hodgson, Louis, Sub Cell Biology, Akhmanova, Anna, ter Hoeve, Natalie D.   +15 more
core   +2 more sources

Neuromorphic place cells

Neuromorphic Computing and Engineering
Abstract A neuromorphic simultaneous localization and mapping (SLAM) system shows potential for more efficient implementation than its traditional counterpart. At the mean time a neuromorphic model of spatial encoding neurons in silicon could provide insights on the functionality and dynamic between each group of cells.
Zhaoqi Chen, Alia Nasrallah, Ralph Etienne-Cummings   +2 more
openaire   +3 more sources

Place-cell and snippet coding.

, 2019
Panel A represents the place-cell activations that correspond to a single point. Place-cell centers are represented by red points and the mean firing rate of each place-cell by a red circle with a fixed radius, centered on the place-cell center.
Martin Llofriu Alonso (6954389), Tatiana Pelc (6954395), Peter Ford Dominey (278909), Pablo Scleidorovich Chiodi (6954392), Nicolas Cazin (6954386), Jean-Marc Fellous (127113), Bruce Harland (6954398), Alfredo Weitzenfeld (6954401)   +7 more
core   +1 more source

p57(Kip2) imposes the reserve stem cell state of gastric chief cells

, 2022
Adult stem cells constantly react to local changes to ensure tissue homeostasis. In the main body of the stomach, chief cells produce digestive enzymes; however, upon injury, they undergo rapid proliferation for prompt tissue regeneration.
Ju, Young Seok, Caldwell, Brianna, Wu, Szu-Hsien Sam, Choi, Eunyoung, Stange, Daniel E., Park, JinYoung, Bamford, Aileen-Diane, Kim, Somi, Kim, Jihoon, An, Yohan, Bon-kyoung Koo, Kim, Jong Kyoung, Rocha, Andreia Sofia Batista, Pilat-Carotta, Sandra, Josserand, Manon, Lee, Heetak, Han, Seungmin, Lee, Ji-Hyun, Philpott, Anna, Fink, Juergen, Szep-Bakonyi, Réka, Min, Jimin, Koo, Bon-Kyoung, Lee, Sieun, Simons, Benjamin D.   +24 more
core   +1 more source

Long-term transverse imaging of the hippocampus with glass microperiscopes

eLife, 2022
The hippocampus consists of a stereotyped neuronal circuit repeated along the septal-temporal axis. This transverse circuit contains distinct subfields with stereotyped connectivity that support crucial cognitive processes, including episodic and spatial
William T Redman, Nora S Wolcott, Luca Montelisciani, Gabriel Luna, Tyler D Marks, Kevin K Sit, Che-Hang Yu, Spencer Smith, Michael J Goard   +8 more
doaj   +1 more source

Place-cell phase precession in marmoset hippocampus.

, 2019
(A) The phase-location correlation ρ is plotted against the log p-value in panel A for all place cells indicated by black dots, with neurons clearing the p-value threshold circled in red. Neurons exhibiting significant θ phase precession (p p = 0.019 BT).
Hristos S. Courellis (8103404), Geoffrey W. Diehl (8103413), Robert Bussell (2740429), Gert Cauwenberghs (371489), Cory T. Miller (3254919), Samuel U. Nummela (8103407), Michael Metke (8103410)   +6 more
core   +1 more source

Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma [PDF]

, 2021
ADAPTeR is a prospective, phase II study of nivolumab (anti-PD-1) in 15 treatment-naive patients (115 multiregion tumor samples) with metastatic clear cell renal cell carcinoma (ccRCC) aiming to understand the mechanism underpinning therapeutic response.
Schnidrig, D, Sunderland, MW, Ghorani, E, Lingard, K, Rowan, A, Jamal-Hanjani, M, Litchfield, K, Turajlic, S, Becker, PD, Swanton, C, Borg, E, PEACE Consortium, Hatipoglu, E, Mahadeva, U, Xu, H, Hazell, S, Mitchison, M, Green, A, TRACERx Renal Consortium, Reading, JL, Sarker, S, Robert de Massy, M, Nicol, D, TRACERx Renal Consortium,, Falzon, M, López, JI, Edmonds, K, Carlyle, E, Mason, R, Salgado, R, Vasquez, MD, Uddin, I, Au, L, Proctor, I, Yang, WW, Quezada, SA, Spencer, C, Fotiadis, N, Shepherd, STC, Mangwende, M, Dhillon, K, Joshi, K, Lund, T, Byrne, F, Horswell, S, Beattie, G, Moore, DA, PEACE Consortium,, Furness, AJS, Puccio, I, Akarca, A, Thompson, R, Larkin, J, Chain, B, Del Rosario, L, Fendler, A, Pickering, L, Kassiotis, G, Marafioti, T, Attig, J   +59 more
core   +1 more source