Results 11 to 20 of about 987,131 (263)
Frontiers in Systems Neuroscience, 2021 This article describes a neural model of the anatomy, neurophysiology, and functions of intrinsic and extrinsic theta rhythms in the brains of multiple species.
Stephen Grossberg
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Cell Reports, 2013 H2O2 can cause oxidative damage associated with age-related diseases such as diabetes and cancer but is also used to initiate diverse responses, including increased antioxidant gene expression.
Jonathon D. Brown +5 more
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Place, space and memory cells [PDF]
Current Biology, 2012 SummarySelf-localization and navigation are critical functions for the survival of mobile animals. By processing sensory information such as landmarks and environmental features, as well as keeping track of the path they have taken, animals are able to remain oriented as they explore the world, learning what resources are where and planning how to ...
Marozzi, Elizabeth, Jeffery, Kathryn J.
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Cl-out is a novel cooperative optogenetic tool for extruding chloride from neurons
Nature Communications, 2016 Chloride regulation is important for setting GABAergic reversal potential, though tools to manipulate chloride levels are limited. Here, the authors combine Archaerhodopsin with a chloride channel opsin to generate an optogenetic chloride extrusion ...
Hannah Alfonsa +3 more
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Engineered kinesin motor proteins amenable to small-molecule inhibition
Nature Communications, 2016 The use of specific small molecule inhibitors can contribute to the study of kinesins' cellular functions. Here the authors develop a chemical-genetic approach to engineer kinesin motors that can be efficiently inhibited upon addition of cell-permeable ...
Martin F. Engelke +10 more
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eLife, 2016 Many recent models study the downstream projection from grid cells to place cells, while recent data have pointed out the importance of the feedback projection. We thus asked how grid cells are affected by the nature of the input from the place cells. We
Yedidyah Dordek +3 more
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Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1
Nature Communications, 2018 The meiotic telomere complex (MAJIN, TERB1, TERB2) tethers telomere ends to the nuclear envelope. Here the authors present the crystal structure of human MAJIN-TERB2 and combine biophysical approaches and structured illumination microscopy analysis of ...
James M. Dunce +6 more
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Hierarchical organization of context in the hippocampal episodic code
eLife, 2013 The hippocampal system appears to be critically important in establishing episodic memory of both internal and external events within contexts as well as spatial memory, which enables flexible spatial navigation.
Susumu Takahashi
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Rigid firing sequences undermine spatial memory codes in a neurodegenerative mouse model
eLife, 2013 Hippocampal neurons encode spatial memories by firing at specific locations. As the animal traverses a spatial trajectory, individual locations along the trajectory activate these neurons in a unique firing sequence, which yields a memory code ...
Jingheng Cheng, Daoyun Ji
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Prefrontal synaptic activation during hippocampal memory reactivation
Cell Reports, 2021 Summary: Cooperative reactivation of hippocampal and prefrontal neurons is considered crucial for mnemonic processes. To directly record synaptic substances supporting the interregional interactions, we develop concurrent spike recordings of hippocampal ...
Yuya Nishimura +2 more
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