Results 21 to 30 of about 9,473,872 (308)
Rigid firing sequences undermine spatial memory codes in a neurodegenerative mouse model
eLife, 2013 Hippocampal neurons encode spatial memories by firing at specific locations. As the animal traverses a spatial trajectory, individual locations along the trajectory activate these neurons in a unique firing sequence, which yields a memory code ...
Jingheng Cheng, Daoyun Ji
doaj +1 more source
Prefrontal synaptic activation during hippocampal memory reactivation
Cell Reports, 2021 Summary: Cooperative reactivation of hippocampal and prefrontal neurons is considered crucial for mnemonic processes. To directly record synaptic substances supporting the interregional interactions, we develop concurrent spike recordings of hippocampal ...
Yuya Nishimura +2 more
doaj +1 more source
Place, space and memory cells [PDF]
Current Biology, 2012 SummarySelf-localization and navigation are critical functions for the survival of mobile animals. By processing sensory information such as landmarks and environmental features, as well as keeping track of the path they have taken, animals are able to remain oriented as they explore the world, learning what resources are where and planning how to ...
Marozzi, Elizabeth, Jeffery, Kathryn J.
openaire +2 more sources
A boundary vector cell model of place field repetition [PDF]
, 2018 Hippocampal place cells are thought to form the neural substrate of a global cognitive map. However, in multicompartment mazes these cells exhibit locally repeating representations, undermining the global cognitive map view of place cells.
Duvelle, E. +5 more
core +1 more source
Hippocampal Place Cell Instability after Lesions of the Head Direction Cell Network [PDF]
, 2003 The occurrence of cells that encode spatial location (place cells) or head direction (HD cells) in the rat limbic system suggests that these cell types are important for spatial navigation.
Dudchenko, Paul +11 more
core +1 more source
Episodic-like memory trace in awake replay of hippocampal place cell activity sequences
eLife, 2015 Episodic memory retrieval of events at a specific place and time is effective for future planning. Sequential reactivation of the hippocampal place cells along familiar paths while the animal pauses is well suited to such a memory retrieval process.
Susumu Takahashi
doaj +1 more source
Identifying Core Regions for Path Integration on Medial Entorhinal Cortex of Hippocampal Formation
Brain Sciences, 2020 Path integration is one of the functions that support the self-localization ability of animals. Path integration outputs position information after an animal’s movement when initial-position and movement information is input.
Ayako Fukawa +3 more
doaj +1 more source
Multi-Scale Extension in an Entorhinal-Hippocampal Model for Cognitive Map Building
Frontiers in Neurorobotics, 2021 Neuroscience research shows that, by relying on internal spatial representations provided by the hippocampus and entorhinal cortex, mammals are able to build topological maps of environments and navigate.
Jiru Wang, Rui Yan, Huajin Tang
doaj +1 more source
Intracellular Dynamics of Virtual Place Cells [PDF]
Neural Computation, 2011 The pattern of spikes recorded from place cells in the rodent hippocampus is strongly modulated by both the spatial location in the environment and the theta rhythm. The phases of the spikes in the theta cycle advance during movement through the place field.
Sandro Romani +2 more
openaire +2 more sources
Bidirectional synaptic plasticity rapidly modifies hippocampal representations
eLife, 2021 Learning requires neural adaptations thought to be mediated by activity-dependent synaptic plasticity. A relatively non-standard form of synaptic plasticity driven by dendritic calcium spikes, or plateau potentials, has been reported to underlie place ...
Aaron D Milstein +6 more
doaj +1 more source