Results 171 to 180 of about 16,525,519 (328)
Place cells are nonrandomly clustered by field location in CA1 hippocampus. [PDF]
Hippocampus, 2023 Wirtshafter HS, Disterhoft JF.
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Utilisation of coal in direct carbon fuel cells
, 2015 The authors thank the Research fund for coal and steel for supporting this research, Grant Agreement Number: RFCR CT-2011-00004.Hybrid Direct Carbon Fuel Cells merge Solid Oxide Fuel Cell (SOFC) and MCFC technologies, using a solid oxide electrolyte to ...
Mottram, Andrew +5 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Modelling directional firing properties of place cells
, 2008 . According to experimental data, hippocampal place cells are mostly directional when a rat is in radial or +-mazes, whereas most place cells are non-directional in open environments.
Wulfram Gerstner +2 more
core
Enhanced Reactivation of Remapping Place Cells during Aversive Learning. [PDF]
J Neurosci, 2023 Ormond J, Serka SA, Johansen JP.
europepmc +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Interactions between classical place cells and other pyramidal cells.
, 2016 (A) The densities of likelihood ratios for place-place, place-other, and other-other digrams (2-element sequences) qualitatively show no preference for classical place cells to fire with other classical place cells (blue density) or other pyramidal cells
Rod C. Scott (498608) +3 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The cerebellum promotes sequential foraging strategies and contributes to the directional modulation of hippocampal place cells. [PDF]
iScience, 2023 Zhang L +5 more
europepmc +1 more source