Results 181 to 190 of about 8,800,807 (297)

Simultaneous path-integration recalibration in head direction and place cells. [PDF]

Curr Biol
Jayakumar RP, Sueoka Y, Ferreyros MK, Li BY, Madhav MS, Chen X, Knierim JJ, Cowan NJ.   +7 more
europepmc   +1 more source

Tetrode recording of rat CA1 place cells in an observational spatial working memory task. [PDF]

STAR Protoc, 2022
Mou X, Suresh P, Ji D.
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Brain region-specific gain modulation of place cells by VIP neurons. [PDF]

Nat Commun
Lenkey N, Garvert AC, Neubrandt M, Kriener B, Vervaeke K.   +4 more
europepmc   +2 more sources

Place cells in CA1 lack topographical organization of firing locations. [PDF]

Proc Natl Acad Sci U S A
Slettmoen T, de Jong NL, Eneqvist H, Skytøen ER, Zong W, Moser MB, Moser EI.   +6 more
europepmc   +1 more source

Task-selective place cells show behaviorally driven dynamics during learning and stability during memory recall. [PDF]

Cell Rep, 2022
Zemla R, Moore JJ, Hopkins MD, Basu J.
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Beyond place cells: Specific and cooperative roles of hippocampal interneuron families in spatial coding. [PDF]

Fundam Res
Cao JW, Jiang C.
europepmc   +1 more source

Place cells dynamically refine grid cell activities to reduce error accumulation during path integration in a continuous attractor model. [PDF]

Sci Rep, 2022
Fernandez-Leon JA, Uysal AK, Ji D.
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source