Results 161 to 170 of about 16,525,519 (328)

Evidence of spatial periodic firing in the subiculum of mice

open access: yesFrontiers in Neural Circuits
The subiculum is a critical node of the hippocampal formation, integrating multiple circuits—including thalamic inputs and afferents from CA1 and medial entorhinal cortex—and projecting broadly to cortical and subcortical targets. Yet its contribution to
P. Abad-Perez   +19 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

A contextual fear conditioning paradigm in head-fixed mice exploring virtual reality

open access: yeseLife
Contextual fear conditioning (CFC) is a classical laboratory task that tests associative memory formation and recall. Techniques such as multi-photon microscopy and holographic stimulation offer tremendous opportunities to understand the neural ...
Seetha Krishnan   +5 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Multimodal firing fields of place cells in large spaces.

open access: yes, 2013
(a) Data showing a histogram of the number of place fields, in a circular box with a diameter of 200 cm, for dorsal cells in proximal CA1 [6]. (b) Corresponding model simulations for the number of learned place fields, in a square box of 100 cm×100 cm ...
Stephen Grossberg (304121)   +1 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Spatial navigation and multiscale representation by hippocampal place cells

open access: yes, 2011
Hippocampal lesions are known to impair success in navigation tasks. While such tasks could be solved by memorizing complete paths from a starting location to the goal, animals still perform successfully when placed in a novel starting position.
Jason Prentice   +3 more
core   +1 more source

Leveraging place field repetition to understand positional versus nonpositional inputs to hippocampal field CA1

open access: yeseLife
The hippocampus is believed to encode episodic memory by binding information about the content of experience within a spatiotemporal framework encoding the location and temporal context of that experience.
William Hockeimer   +4 more
doaj   +1 more source

Do Place Cells Dream of Deceptive Moves in a Signaling Game? [PDF]

open access: yesNeuroscience, 2023
Fenton AA   +4 more
europepmc   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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