Results 41 to 50 of about 1,501,016 (387)

Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk: The CARMELINA Randomized Clinical Trial

Journal of the American Medical Association (JAMA), 2019
Importance Type 2 diabetes is associated with increased cardiovascular (CV) risk. Prior trials have demonstrated CV safety of 3 dipeptidyl peptidase 4 (DPP-4) inhibitors but have included limited numbers of patients with high CV risk and chronic kidney ...
J. Rosenstock, V. Perkovic, O. Johansen, M. Cooper, S. Kahn, N. Marx, J. Alexander, M. Pencina, R. Toto, C. Wanner, B. Zinman, H. Woerle, David Baanstra, E. Pfarr, S. Schnaidt, T. Meinicke, J. George, M. von Eynatten, D. McGuire   +18 more
semanticscholar   +1 more source

A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis.

New England Journal of Medicine, 2010
BACKGROUND Oral fingolimod, a sphingosine-1-phosphate-receptor modulator that prevents the egress of lymphocytes from lymph nodes, significantly improved relapse rates and end points measured on magnetic resonance imaging (MRI), as compared with either ...
L. Kappos, E. Radue, P. O'Connor, C. Polman, R. Hohlfeld, P. Calabresi, K. Selmaj, C. Agoropoulou, M. Leyk, Lixin Zhang-Auberson, P. Burtin   +10 more
semanticscholar   +1 more source

Intravenous iron supplementation treats anemia and reduces blood transfusion requirements in patients undergoing coronary artery bypass grafting—A prospective randomized trial

Annals of Cardiac Anaesthesia, 2022
Study Objective: Preoperative anemia results in two- to sixfold increased incidence of perioperative blood transfusion requirements and reduced postoperative hemoglobin (Hb) level.
Hoda Shokri, Ihab Ali
doaj   +1 more source

Can Intracommunicology Assist the Philosophy of the Media? [PDF]

In Medias Res, 2020
In 2014, the famous researcher and Nobel laureate Bruce Lipton proved that human thoughts, not just thinking, are energy, they are real and have power. “‘Do not doubt that you command your body and mind... If thoughts are weak and life is like that.
Fahira Fejzić-Čengić
doaj   +1 more source

Cognitive behavioral therapy for anxiety and related disorders: A meta‐analysis of randomized placebo‐controlled trials

Depression and Anxiety, 2018
The purpose of this study was to examine the efficacy of cognitive behavioral therapy (CBT) for anxiety‐related disorders based on randomized placebo‐controlled trials.
Joseph K. Carpenter, Leigh A Andrews, S. Witcraft, Mark B. Powers, Jasper A. J. Smits, S. Hofmann   +5 more
semanticscholar   +1 more source

Cost-effectiveness analyses for mirtazapine and sertraline in dementia: randomised controlled trial [PDF]

, 2012
BACKGROUND Depression is a common and costly comorbidity in dementia. There are very few data on the cost-effectiveness of antidepressants for depression in dementia and their effects on carer outcomes. AIMS To evaluate the cost-effectiveness of
Alan Thomas, Alistair Burns, Bains, Beecham, Chris Fox, Claire Lawton, Clive Ballard, Clive Holmes, Cornelius Katona, Curtis, Dolan, Esme Moniz-Cook, Gill Livingston, James Lindesay, Jennifer Hellier, Joanna Murray, John O'Brien, Kales, Kenneth Wilson, Martin Knapp, Michael Dewey, Michaela Poppe, Niall McCrae, Peter Bentham, Rebecca Walwyn, Renee Romeo, Robert Baldwin, Shirley Nurock, Sube Banerjee, Wimo   +29 more
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Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial.

New England Journal of Medicine, 1991
BACKGROUND AND METHODS In the Cardiac Arrhythmia Suppression Trial, designed to test the hypothesis that suppression of ventricular ectopy after a myocardial infarction reduces the incidence of sudden death, patients in whom ventricular ectopy could be ...
D. Echt, P. Liebson, L. Mitchell, R. Peters, D. Obias-Manno, A. H. Barker, D. Arensberg, A. Baker, Lawrence M. Friedman, H. Greene, M. Huther, D. Richardson   +11 more
semanticscholar   +1 more source

Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness [PDF]

, 2018
BACKGROUND: There are conflicting data on the effects of antipsychotic medications on delirium in patients in the intensive care unit (ICU). METHODS: In a randomized, double-blind, placebo-controlled trial, we assigned patients with acute ...
Bernard, G.R., Boehm, L.M., Bowton, D.L., Brummel, N.E., Carson, S.S., Chandrasekhar, R., Dittus, R.S., Douglas, I.S., Ely, E.W., Exline, M.C., Feinstein, D.J., Girard, T.D., Gong, M.N., Hite, R.D., Hough, C.L., Hughes, C.G., Hyzy, R.C., Jackson, J.C., Khan, B., Malhotra, A., Masica, A.L., Owens, R.L., Pandharipande, P.P., Patel, M.B., Pisani, M.A., Pun, B.T., Rock, P., Schmidt, G.A., Schweickert, W.D., Stollings, J.L., Strength, C., Thompson, J.L.   +31 more
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A randomized, placebo‐controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis

Hepatology, 2018
The aim of this study was to evaluate cenicriviroc (CVC), a dual antagonist of CC chemokine receptor types 2 and 5, for treatment of nonalcoholic steatohepatitis (NASH) with liver fibrosis (LF).
S. Friedman, V. Ratziu, S. Harrison, M. Abdelmalek, G. Aithal, J. Caballería, S. Francque, G. Farrell, K. Kowdley, A. Craxì, K. Simon, L. Fischer, Liza Melchor-Khan, Jeffrey D. Vest, B. Wiens, P. Vig, S. Seyedkazemi, Z. Goodman, V. Wong, R. Loomba, F. Tacke, A. Sanyal, E. Lefebvre   +22 more
semanticscholar   +1 more source

Evaluation of Pain on Probing using Anaesthetic Gel in Chronic Periodontitis Patients with True Pressure Sensitive Probe: A Placebo Controlled Trial [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Periodontal diagnosis and treatment plan rely on an important aspect which is called as the periodontal probing. However, probing has proven to be a painful procedure especially in untreated chronic periodontitis patients.
Siddani Siva Vara Prasad, Anil Kumar Kancharla, Shareen Babu Perika, Pandranki Divya Deepthi, Anwesh Reddy Nandigam, Mohammad Sheema Tasneem, Billa Sowjanya Reddy, Shruthi Akilandan   +7 more
doaj   +1 more source