Results 61 to 70 of about 1,543,966 (410)

Regulation with Placebo Effects [PDF]

, 2008
A growing scientific literature supports the existence of placebo effects from a wide range of health interventions and for a range of medical conditions.
Malani, Anup
core   +1 more source

Change in Cognition Following Ischaemic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline can occur following ischaemic stroke. How cognition changes over time and associations with cognitive change are poorly understood. This study aimed to explore these issues over 2 years following ischaemic stroke.
Wenci Yan, Terence Quinn, Alex McConnachie, Niall Broomfield, Yun Wong, David Dickie, Kirsten Forbes, Matthew Walters, Jesse Dawson   +8 more
wiley   +1 more source

Critical appraisal and update on the clinical utility of agomelatine, a melatonergic agonist, for the treatment of major depressive disease in adults [PDF]

, 2009
This article describes the pharmacology of the novel atypical antidepressant drug agomelatine, critically reviews and evaluates its clinical use for the treatment of major depression, and suggests areas for further research.
Howland, RH
core   +1 more source

Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and CSF Cell Composition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich, Tilman Schneider‐Hohendorf, Eric Baetscher, Evan L. Riddle, Marie Deffner, Emily Katsnelson, Janine Ferrant‐Orgettas, Julie Czerkowicz, John Anderson, Susan E. Goelz, Nicholas Schwab   +10 more
wiley   +1 more source

A comparative evaluation of propolis and light-cured ormocer-based desensitizer in reducing dentin hypersensitivity

Journal of Indian Society of Periodontology, 2020
Objectives: The purpose of the study was to evaluate and compare the clinical efficacy and the durability of propolis and Light-cured ormocer-based desensitizer (Admira Protect, Voco: Cuxhaven Germany) in the treatment of dentin hypersensitivity (DH ...
Snigdha Maity, Vidya Priyadharshini, Suman Basavaraju   +2 more
doaj   +1 more source

Study of the placebo effect with a placebo test

Comprehensive Psychiatry, 1968
Summary This paper briefly reviewed several methodological problems in studies of the placebo effect. The importance of finding appropriate measures of placebo effect was emphasized. This led to an attempt to develop a more valid and reliable test of placebo reactivity.
A K, Shapiro, H, Wilensky, E L, Struening   +2 more
openaire   +2 more sources

Domain Specific Placebo Response in the Modified Friedreich's Ataxia Rating Scale

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The placebo response in clinical trials in ataxias complicates outcome interpretation and potentially obscures genuine treatment effects. We analyzed placebo group data from past trials in Friedreich Ataxia and observed notable responses in appendicular items, in contrast to minimal changes in axial function, as measured by respective ...
Christian Rummey, Jennifer M. Farmer, David R. Lynch   +2 more
wiley   +1 more source

An update on non-pharmacological interventions for pain relief

Cell Reports Medicine
Summary: Chronic pain affects a substantial portion of the population, yet current treatments often fail to provide adequate relief. Non-pharmacological interventions, which target behaviors and brain processes underlying the experience of pain, hold ...
Yang Wang, Rachel Aaron, Nadine Attal, Luana Colloca   +3 more
doaj   +1 more source

Randomized double-blind placebo-controlled trial of 40 mg/day of atorvastatin in reducing the severity of sepsis in ward patients (ASEPSIS Trial) [PDF]

, 2012
Introduction: Several observational studies suggest that statins modulate the pathophysiology of sepsis and may prevent its progression. The aim of this study was to determine if the acute administration of atorvastatin reduces sepsis progression in ...
Barnett, A. H., Cooke, Matthew, Hawkey, P. M., Hong, Tan, Jones, Alan, Linhartova, Lucie, Melody, Teresa, Patel, Jaimin M., Perkins, Gavin D., Smith, F. Gao, Snaith, Catherine, Thickett, David R.   +11 more
core   +3 more sources

A Placebo‐Controlled Trial of Bezafibrate in Primary Biliary Cholangitis

New England Journal of Medicine, 2018
Background Patients with primary biliary cholangitis who have an inadequate response to therapy with ursodeoxycholic acid are at high risk for disease progression.
C. Corpechot, O. Chazouilleres, A. Rousseau, Antonia Le Gruyer, F. Habersetzer, P. Mathurin, O. Goria, P. Potier, A. Minello, C. Silvain, A. Abergel, M. Debette‐Gratien, D. Larrey, O. Roux, J. Bronowicki, J. Boursier, V. de Lédinghen, A. Heurgue-berlot, E. Nguyen-Khac, F. Zoulim, I. Ollivier-Hourmand, J. Zarski, G. Nkontchou, S. Lemoinne, L. Humbert, D. Rainteau, G. Lefèvre, L. de Chaisemartin, S. Chollet-Martin, F. Gaouar, Farid-Hakeem Admane, T. Simon, R. Poupon   +32 more
semanticscholar   +1 more source