Results 121 to 130 of about 1,288,236 (382)

The effect of 14 weeks of vitamin D3 supplementation on antimicrobial peptides and proteins in athletes [PDF]

open access: yes, 2016
Heavy training is associated with increased respiratory infection risk and antimicrobial proteins are important in defence against oral and respiratory tract infections.
Cheng-Shiun He   +9 more
core   +1 more source

Effectiveness and Safety of Oral Azvudine for Elderly Hospitalized Patients With COVID‐19: A Multicenter, Retrospective, Real‐World Study

open access: yesAdvanced Science, EarlyView.
This multicenter, retrospective, real‐world study enrolls the largest hospitalized elderly cohort of COVID‐19 patients from nine hospitals in Henan Province to investigate the effectiveness and safety of Azvudine. The results show that compared controls, Azvudine treatment can reduce the rate of all‐cause death in elderly patients with COVID‐19, and ...
Ranran Sun   +20 more
wiley   +1 more source

Exposing the evidence gap for complementary and alternative medicine to be integrated into science-based medicine. [PDF]

open access: yes, 2011
When people who advocate integrating conventional science-based medicine with complementary and alternative medicine (CAM) are confronted with the lack of evidence to support CAM they counter by calling for more research, diverting attention to the ...
Hopayian, K, Power, M.
core   +1 more source

Programmable NIR Responsive Nanocomposite Enables Noninvasive Intratympanic Delivery of Dexamethasone to Reverse Cisplatin Induced Hearing Loss

open access: yesAdvanced Science, EarlyView.
In this study, saponin‐coated silica@gold nanocarriers responsive to NIR radiation is developed to enhance intratympanic drug delivery for cisplatin‐induced hearing loss (CIHL) treatment. The biocompatibility and oto‐protective properties are validated both in vitro and in vivo.
Rawand A. Mustafa   +6 more
wiley   +1 more source

The effect of carbohydrate ingestion on the Interleukin-6 response to a 90-minute run time trial [PDF]

open access: yes, 2009
Fatigue is a predictable outcome of prolonged physical activity; yet its biological cause remains uncertain. During exercise, a polypeptide messenger molecule interleukin- 6 (IL-6) is actively produced.
Ansley, Les   +3 more
core   +1 more source

YC‐4‐3, a Novel Glycogen Synthase Kinase 3β Inhibitor, Alleviates the Endoplasmic Reticulum Stress of Macrophages in Primary Immune Thrombocytopenia

open access: yesAdvanced Science, EarlyView.
A patented GSK‐3β inhibitor (GSK‐3βi), new benzothiazepinone compounds (BTZs), YC‐4‐3, can modulate the inflammatory status of macrophages in primary immune thrombocytopenia (ITP), and improve the thrombocytopenia in murine ITP models by directly interacting with endoplasmic reticulum (ER) stress response.
Pengcheng Xu   +10 more
wiley   +1 more source

Mixed Spices at Culinary Doses Have Prebiotic Effects in Healthy Adults: A Pilot Study. [PDF]

open access: yes, 2019
Spices were used as food preservatives prior to the advent of refrigeration, suggesting the possibility of effects on microbiota. Previous studies have shown prebiotic activities in animals and in vitro, but there has not been a demonstration of ...
Carpenter, Catherine L   +11 more
core   +1 more source

Advances in Fecal Microbiota Transplantation for Gut Dysbiosis‐Related Diseases

open access: yesAdvanced Science, EarlyView.
This article reviews the use of fecal microbiota transplantation (FMT) to treat intestinal diseases like recurrent Clostridioides difficile infection (rCDI), inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS). It discusses FMT's efficacy, influencing factors such as donor selection, recipient characteristics, and treatment protocols ...
Shuna Hou   +4 more
wiley   +1 more source

Systematic review of antitumour efficacy and mechanism of metformin activity in prostate cancer models

open access: yesBJUI Compass, Volume 4, Issue 1, Page 44-58, January 2023., 2023
Abstract Metformin, the first line pharmacotherapy for type 2 diabetes has demonstrated favourable effects in prostate cancer (PCa) across a range of studies evaluating PCa patient outcomes amongst metformin users. However, a lack of rigorously conducted prospective studies has stalled clinical use in this setting.
Nan Fang Wang   +3 more
wiley   +1 more source

La investigación: Un placebo para los que ven en ella un camino al reconocimiento investigação: um placebo para os que vêem nela um caminho ao reconhecimento Research: Placebo for those who see a way to recognition on it

open access: yesInvestigación y Educación en Enfermería, 2012
En este artículo se discute el sentido que debe tener la investigación como herramienta de aproximación a la realidad cotidiana y del papel del investigador como agente de cambio social.Neste artigo se discute o sentido que deve ter a investigação como ...
Johan Sebastián Lopera Valle
doaj  

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