Results 141 to 150 of about 9,905,323 (311)

Integrating Genetic Modifier Genotype With Serum Proteomics in Duchenne Muscular Dystrophy Clinical Trials Links LTBP4 Genetic Modifier to IL‐23/CD93 Pathways in Muscle

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genetic modifiers of Duchenne muscular dystrophy (DMD) that alter disease severity or response to therapy have been reported using natural history or registry data sets of older corticosteroid‐treated patients. We tested associations of genetic modifiers on motor function outcomes in young (4 to < 7 years) steroid naïve clinical trial ...
Utkarsh J. Dang   +16 more
wiley   +1 more source

[The concept of placebo and the effect of placebo].

open access: yesTurk psikiyatri dergisi = Turkish journal of psychiatry, 2004
The discussions about what placebo means and how its effect occurs go far back in the history of medicine. In general medicinal understanding, placebo means the subjective feeling of a positive effect in response to something that is used for curative intentions. In spite of difficulties in its definition and unknown content, its existence is generally
openaire   +1 more source

The placebo effect in our everyday lives

open access: yes
reservedSpesso le nostre scelte di vita quotidiana sono governate da delle forze a noi estranee che inconsapevolmente influiscono sul nostro comportamento.
GENOVESI, MARTA
core  

Testing for Placebo Effects Using Data from Blinded, Randomized Controlled Trials [PDF]

open access: yes
This paper proposes a test for the existence of placebo effects, as described by the so-called expectancy theory. This theory, which is the dominant medical theory of how placebo effects operate, posits that health outcomes rise in individuals' beliefs ...
Anup Malani
core  

Lost and Found: Is Olfactory Recovery More Promising After COVID‐19 Than Other Causes, Even 2 Years Later?

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Olfactory dysfunction is a hallmark feature of COVID‐19, yet the potential for recovery with long‐standing COVID‐19‐related smell loss (CRSL) remains uncertain, particularly when treatment is initiated years later. This study evaluated olfactory outcomes in patients with CRSL compared with non‐COVID‐19‐related smell loss (non‐CRSL),
John W. Hunsicker   +6 more
wiley   +1 more source

Computational Psychiatry and the Placebo Effect in Psychosis. [PDF]

open access: yesBiol Psychiatry Glob Open Sci, 2023
Atlas LY.
europepmc   +1 more source

Tezepelumab in Chinese Patients With Severe Chronic Rhinosinusitis With Nasal Polyps: A Prespecified Subgroup Analysis of the Phase 3 WAYPOINT Trial

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) in Chinese patients often exhibits a mixed Type 1/2/3 inflammatory phenotype (63%), potentially impacting the efficacy of biologics targeting Type 2 inflammation. This prespecified subgroup analysis of WAYPOINT (NCT04851964) evaluated the efficacy and safety of tezepelumab in Chinese
Li Hu   +9 more
wiley   +1 more source

Shaping Treatment Expectation to Optimize Efficacy of Interleukin 17A Antagonist Secukinumab in Psoriasis Patients

open access: yesPsoriasis: Targets and Therapy
Stefanie Hölsken,1 Frederik Krefting,2 Senta Mühlhaus,2 Daniela Bese,2 Manfred Schedlowski,1,3 Wiebke Sondermann2 1Institute of Medical Psychology and Behavioral Immunobiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany ...
Hölsken S   +5 more
doaj  

The placebo effect in reading: a possible relationship with personality traits

open access: yes
reservedLa ricerca ha avuto lo scopo di verificare se sia possibile rilevare un effetto placebo nelle abilità di lettura e se vi sia una relazione tra l’effetto placebo e i tratti di personalità.
TALARICO, CHIARA
core  

The Placebo and Nocebo Effect: the brain's power in modulating our perceptions [PDF]

open access: yes
openLa tesi esplorerà i fenomeni dell'Effetto Placebo e Nocebo, mettendone in luce i meccanismi sottostanti, sia neurali che psicosociali. In particolare, verranno esaminati fattori come le aspettative, il condizionamento, la componente genetica e la ...
BELLIO, AURORA
core  

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