Results 151 to 160 of about 410,688 (266)

Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults

Autism Research, EarlyView.
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin, Arthur N. Westover, Amy S. F. Lutz, Manish K. Jha   +3 more
wiley   +1 more source

Triadic relations in healthcare: surveying physicians' perspectives on generative AI integration and its role on empathy, the placebo effect and patient care. [PDF]

Front Psychol
Faria V, Goturi N, Dynak A, Talbert C, Pondelis N, Annoni M, Blease C, Holmes SA, Moulton EA.   +8 more
europepmc   +1 more source

Real effect vs placebo effect. [PDF]

J Clin Sleep Med, 2021
Hunasikatti M.
europepmc   +1 more source

Current evidence and insights on single vs. double dose of basiliximab in adult solid organ transplant recipients: A systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this systematic review was to assess all available clinical data regarding the use of a single dose of basiliximab in solid organ transplantation compared to the standard double dosage, with particular interest in efficacy, safety and cost‐savings.
Alessio Provenzani, Braidon A. Lape, Anneliese M. Harp, Victoria Weisbrod, Lavinia Piazza   +4 more
wiley   +1 more source

Dose-extending placebo effect in a rat model of buprenorphine maintenance treatment. [PDF]

Psychopharmacology (Berl)
Pitts KM, Pilz EM, Colloca L, Shaham Y, Chow JJ.   +4 more
europepmc   +1 more source

Correction to: Gender-Affirming Treatment of Gender Dysphoria in Youth: A Perfect Storm Environment for the Placebo Effect-The Implications for Research and Clinical Practice. [PDF]

Arch Sex Behav, 2023
Clayton A.
europepmc   +1 more source

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

British Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source

Differential placebo effect of sham acupuncture for chronic pain: a network meta-analysis of randomized controlled trials. [PDF]

BMC Complement Med Ther
Wan R, Zheng Q, Zeng X, Luo Y, Sun L, Chen S, Luo F, Zhang Y, Zhu Z, Chen X, Zhao Y, Li Y.   +11 more
europepmc   +1 more source

Gender-Affirming Treatment of Gender Dysphoria in Youth: A Perfect Storm Environment for the Placebo Effect-The Implications for Research and Clinical Practice. [PDF]

Arch Sex Behav, 2023
Clayton A.
europepmc   +1 more source

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

British Journal of Clinical Pharmacology, EarlyView.
Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort, Marella C. E. van Ruissen, Lisanne C. A. Smidt, Naomi B. Klarenbeek, Philip H. K. Kremer, Manon A. A. Jansen, Jacobus Burggraaf, Joop M. A. van Gerven, Matthijs Moerland   +8 more
wiley   +1 more source