Results 41 to 50 of about 797,570 (234)
A double-blind study of the efficacy of apomorphine and its assessment in "off-periods in Parkinson's disease [PDF]
, 1993 Five patients with idiopathic Parkinson's disease with severe response fluctuations were selected for a randomized double-blind placebo-controlled study, concerning the clinical effects of subcutaneous apomorphine and its assessment in `off¿-periods. The
Essink, A.W.G. +4 more
core +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich +10 more
wiley +1 more source
Should we reconsider the routine use of placebo controls in clinical research?
Trials, 2012 Background Modern clinical-research practice favors placebo controls over usual-care controls whenever a credible placebo exists. An unrecognized consequence of this preference is that clinicians are more limited in their ability to provide the benefits ...
Avins Andrew L +4 more
doaj +1 more source
The hedonic placebo effect of traditional medicines [PDF]
, 2012 To date, the scientific evidence on traditional medicines is scant and under-developed, yet, paradoxically individuals continue to use it and claim high satisfaction levels. What can explain this effect? Using self-collected data from Ghana we argue that
Costa-i-Font, Joan, Sato, Azusa
core
Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes [PDF]
, 2016 Background The cardiovascular effect of liraglutide, a glucagon-like peptide 1 analogue, when added to standard care in patients with type 2 diabetes, remains unknown. Methods In this double-blind trial, we randomly assigned patients with type 2 diabetes
Bergenstal, RM +15 more
core +1 more source
Prophylactic Management of Vestibular Migraine: A Systematic Review
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Vestibular migraine (VM) is a neurological disorder characterized by episodic vertigo in patients with migraine, contributing to substantial functional impairment. Although VM is relatively common, a consensus on effective prophylactic treatments is lacking.
Hussain Ali Almohammed +11 more
wiley +1 more source
Placebo effect associated to artistic products; the case of poetry
Management Letters/Cuadernos de Gestión, 2014 This research finds unambiguous evidence about the existence of the placebo effect in the evaluation of an artistic product, such as a poem. After applying different methods and under disparate test situations, results indicate that the name of the ...
Jose A. Martínez
doaj +1 more source
Racial Differences in the Effect of Granulocyte Macrophage Colony-Stimulating Factor on Improved Walking Distance in Peripheral Artery Disease: The PROPEL Randomized Clinical Trial. [PDF]
, 2019 Background The effects of race on response to medical therapy in people with peripheral artery disease ( PAD ) are unknown. Methods and Results In the PROPEL (Progenitor Cell Release Plus Exercise to Improve Functional Performance in PAD) Trial, PAD ...
Criqui, Michael H +11 more
core +1 more source
The Placebo Effect in Digital Games [PDF]
, 2015 Play-testing of digital games is a crucial part of any game development process, used to gather feedback about the game and correct any existing and potential flaws with the design.
Cairns, P., Denisova, A.
core +2 more sources
Arthritis Care &Research, Accepted Article.Objective This study examined the global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis (OA) burden from 1990 to 2021. Methods Age‐standardized years lived with disability rate for site‐specific OA across 204 countries/territories were obtained from the Global Burden of Diseases Study (GBD) 2021.
Haowei Chen +14 more
wiley +1 more source