In this issue of SLEEP, Kushida and colleagues1 report neurocognitive performance results from a large, multi-site, double blind, controlled, randomized clinical trial on the effects of long-term continuous positive airway pressure (CPAP) therapy.1–3 In this trial, 1,098 patients with obstructive sleep apnea were randomized to active CPAP or sham CPAP (
Schwartz, Skai W.+2 more
openaire +4 more sources
Placebo and the law of identification
Thousands of essays and studies have been published on placebo and nocebo. Yet, despite this plethora of information, we are not much closer to a comprehensive understanding of the fundamental mechanism producing placebo and nocebo effects than we were ...
Steve F. Bierman+2 more
doaj +1 more source
The glycaemic effects of single doses of Panax ginseng in young healthy volunteers [PDF]
The results of two acute placebo-controlled, double-blind cross-over studies assessing the effect of Panax ginseng (G115) on blood glucose levels are reported.
Kennedy, David+2 more
core +1 more source
When a placebo is not a ‘placebo’: a placebo effect on postprandial glycaemia [PDF]
What is already known about this subject • Although placebo effects have been shown on subjective continuous variables such as pain, placebo effects on objective continuous variables remain uncertain.• The present, pilot, follow‐up investigation represents the first to assess a placebo effect on the objective continuous measurement of acute ...
Vladimir Vuksan+3 more
openaire +3 more sources
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness [PDF]
BACKGROUND: There are conflicting data on the effects of antipsychotic medications on delirium in patients in the intensive care unit (ICU). METHODS: In a randomized, double-blind, placebo-controlled trial, we assigned patients with acute ...
Bernard, G.R.+31 more
core +1 more source
"AI enhances our performance, I have no doubt this one will do the same": The Placebo effect is robust to negative descriptions of AI [PDF]
Heightened AI expectations facilitate performance in human-AI interactions through placebo effects. While lowering expectations to control for placebo effects is advisable, overly negative expectations could induce nocebo effects. In a letter discrimination task, we informed participants that an AI would either increase or decrease their performance by
arxiv
Randomised controlled trial of homoeopathy versus placebo in perennial allergic rhinitis with overview of four trial series [PDF]
OBJECTIVE: To test the hypothesis that homoeopathy is a placebo by examining its effect in patients with allergic rhinitis and so contest the evidence from three previous trials in this series.
Aitchison, T,+4 more
core +2 more sources
Decomposing Triple-Differences Regression under Staggered Adoption [PDF]
The triple-differences (TD) design is a popular identification strategy for causal effects in settings where researchers do not believe the parallel trends assumption of conventional difference-in-differences (DiD) is satisfied. TD designs augment the conventional 2x2 DiD with a "placebo" stratum -- observations that are nested in the same units and ...
arxiv
Should we reconsider the routine use of placebo controls in clinical research?
Background Modern clinical-research practice favors placebo controls over usual-care controls whenever a credible placebo exists. An unrecognized consequence of this preference is that clinicians are more limited in their ability to provide the benefits ...
Avins Andrew L+4 more
doaj +1 more source
Glucose and cognitive performance : the effects of glucose on memory and sustained attention : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]
The effects of glucose on tasks of declarative memory, and sustained attention were examined. These effects were also investigated with regard to the age of the participant.
Richardson, Kelly
core