Results 21 to 30 of about 12,173,418 (313)

Placebo use in the United Kingdom: results from a national survey of primary care practitioners [PDF]

open access: yes, 2013
Objectives: Surveys in various countries suggest 17% to 80% of doctors prescribe ‘placebos’ in routine practice, but prevalence of placebo use in UK primary care is unknown.Methods: We administered a web-based questionnaire to a representative sample of ...
Stevens, Sarah   +25 more
core   +1 more source

Placebo and the law of identification

open access: yesFrontiers in Psychiatry
Thousands of essays and studies have been published on placebo and nocebo. Yet, despite this plethora of information, we are not much closer to a comprehensive understanding of the fundamental mechanism producing placebo and nocebo effects than we were ...
Steve F. Bierman   +2 more
doaj   +1 more source

Drug*placebo interaction effect may bias clinical trials interpretation: hybrid balanced placebo and randomized placebo-controlled design

open access: yesBMC Medical Research Methodology, 2016
Background Conventional randomized placebo-controlled study design assumes the absence of drug*placebo interaction. We hypothesized the presence of such an interaction and that conventionally estimated drug effect might be biased.
Muhammad M. Hammami   +5 more
doaj   +1 more source

Patients’ experiences treated with open-label placebo versus double-blind placebo: a mixed methods qualitative study

open access: yesBMC Psychology, 2022
Background There is increasing evidence suggesting that open-label placebo (OLP) is an effective treatment for several medical conditions defined by self-report.
Julia W. Haas   +9 more
doaj   +1 more source

Suggestive Preparation of Patients using Intravenous Ketoprofen as a Part of Postoperative Pain Management in Elective Abdominal Surgery

open access: yesActa Clinica Croatica, 2023
Suggestive preparation before surgery may have a placebo effect and can reduce perioperative consumption of analgesics. A total of 77 adult patients undergoing elective cholecystectomy and hernioplasty were included in this prospective study.
Anja Petričević   +3 more
doaj   +1 more source

A transferable anxiolytic placebo effect from noise to negative effect

open access: yes, 2015
Background: The placebo effect in relieving negative emotion arousal is poorly understood.Aims: We examined whether placebo expectation established with noise stimuli could have a transferable anxiolytic effect on negative emotion arousal.Methods: In ...
Zhang, Jianxin   +5 more
core   +1 more source

The placebo effect in sport: How practitioners can inject words to improve performance

open access: yes, 2020
Placebo effects are a complex interplay between an intervention* and factors associated with the administration of that intervention, such as expectations, previous experiences and interactions between participant and researcher.1 While researchers often
Roelands, B.   +3 more
core   +1 more source

Study of the placebo effect with a placebo test

open access: yesComprehensive Psychiatry, 1968
Summary This paper briefly reviewed several methodological problems in studies of the placebo effect. The importance of finding appropriate measures of placebo effect was emphasized. This led to an attempt to develop a more valid and reliable test of placebo reactivity.
A K, Shapiro   +2 more
openaire   +2 more sources

The Hawthorne Effect: a randomised, controlled trial [PDF]

open access: yes, 2007
Background: The 'Hawthorne Effect' may be an important factor affecting the generalisability of clinical research to routine practice, but has been little studied.
Griffin, M   +17 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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