Results 41 to 50 of about 9,905,323 (311)

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source

EL PLACEBO: LUCES Y SOMBRAS Placebo: Lights and shadows

Revista Habanera de Ciencias Médicas, 2008
Se realiza una revisión sobre el placebo definiéndose su concepto, así como del efecto placebo, sus reacciones en el organismo, utilidad en las investigaciones, sus posibles usos en la práctica médica y los peligros de su empleo.
José Díaz Novás
doaj  

The Role of Expectation and Beliefs on the Effects of Non-Invasive Brain Stimulation

Brain Sciences, 2021
Non-invasive brain stimulation (NIBS) techniques are used in clinical and cognitive neuroscience to induce a mild magnetic or electric field in the brain to modulate behavior and cortical activation.
Miriam Braga, Diletta Barbiani, Mehran Emadi Andani, Bernardo Villa-Sánchez, Michele Tinazzi, Mirta Fiorio   +5 more
doaj   +1 more source

An educational placebo effect intervention reduces the likelihood of athletes using performance enhancing drugs [PDF]

, 2018
Background Recent research has reported that placebo effects can significantly improve sport performance. However, while research has generated knowledge about placebo effects on sport performance, there is limited research devoted to how this can ...
Beedie, C., Hurst, P., Coleman, D., Foad, A.   +3 more
core  

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Should we reconsider the routine use of placebo controls in clinical research?

Trials, 2012
Background Modern clinical-research practice favors placebo controls over usual-care controls whenever a credible placebo exists. An unrecognized consequence of this preference is that clinicians are more limited in their ability to provide the benefits ...
Avins Andrew L, Cherkin Daniel C, Sherman Karen J, Goldberg Harley, Pressman Alice   +4 more
doaj   +1 more source

The placebo and nocebo effect on sports performance: A systematic review [PDF]

, 2019
This is an accepted manuscript of an article published by Taylor and Francis in European Journal of Sport Science on 20/08/2019, available online: https://www.tandfonline.com/doi/full/10.1080/17461391.2019.1655098 The accepted version of the publication
Foad, Abby, Raglin, John S., Lane, A., Raglin, John, Hettinga, F., Coleman, D., Szabo, Attila, Hettinga, Florentina, Raglin, J., Foad, A., Szabo, A., Hurst, Phillip, Coleman, Damian, Roelands, Bart, Roelands, B., Hurst, Philip, Schiphof-Godart, l., Beedie, C., Schipof-Godart, Lieke, Beedie, Chris, Lane, Andrew, Hurst, P.   +21 more
core   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Re-evaluating the placebo response in recent canine dietary epilepsy trials

BMC Veterinary Research
The placebo response is a common phenomenon. Limited evidence is available about its magnitude in canine epilepsy trials, even though it can significantly influence the efficacy evaluation of new treatments.
Teresa Schmidt, Nina Meyerhoff, Sebastian Meller, Friederike Twele, Marios Charalambous, Benjamin A. Berk, Tsz H. Law, Rowena M. A. Packer, Brian Zanghi, Yuanlong Pan, Andrea Fischer, Holger A. Volk   +11 more
doaj   +1 more source