Results 121 to 130 of about 8,509,826 (346)
Neural Patterns of Social Pain in the Brain‐Wide Representations Across Social Contexts
Advanced Science, EarlyView.Empathy arises from both physiological and social pain, yet their shared and context‐specific neural mechanisms remain unclear. Combining fMRI and multivariate pattern analysis, this study decodes overlapping empathy networks and distinct representations for social exclusion versus separation.
Xiaodong Zhang +11 more
wiley +1 more source
Putting climate change at the heart of education: Is England's strategy a placebo for policy?
British Educational Research Journal, Volume 48, Issue 6, Page 1083-1101, December 2022., 2022 Abstract In this paper we present an analysis of the sustainability and climate change strategy for education and children's services systems in England, produced by the Department for Education. Using critical discourse analysis, we juxtapose qualitative data collected from >200 youth teachers and teacher educators in the context of co‐creating a ...
Lynda Dunlop, Elizabeth A. C. Rushton
wiley +1 more source
Placebo response in antipsychotic clinical trials: a meta-analysis.
JAMA psychiatry, 2014 IMPORTANCE Because increasing placebo response rates decrease drug-placebo differences and increase the number of failed trials, it is imperative to determine what is causing this trend.
B. Rutherford +5 more
semanticscholar +1 more source
Targeting miRNA‐1a and miRNA‐15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration
Advanced Science, EarlyView.The article explores a novel therapeutic strategy for cardiac regeneration by targeting miRNA‐1a and miRNA‐15b. Combinatorial inhibition of miR‐1a and miR‐15b enhances cardiomyocyte proliferation, improves heart function, and reduces fibrosis in myocardial infarction models.
Ting Yuan +16 more
wiley +1 more source
Goodness‐of‐fit tests in proportional hazards models with random effects
Biometrical Journal, Volume 65, Issue 1, January 2023., 2023 Abstract This paper deals with testing the functional form of the covariate effects in a Cox proportional hazards model with random effects. We assume that the responses are clustered and incomplete due to right censoring. The estimation of the model under the null (parametric covariate effect) and the alternative (nonparametric effect) is performed ...
Wenceslao González‐Manteiga +2 more
wiley +1 more source
Advanced Science, EarlyView.This study presents receptor‐biased IL‐2 PEGylates that selectively modulate IL‐2 receptor subunit interactions to enhance CD8⁺ T cell antitumor activity while curbing Treg activation and endothelial toxicity. The combined not‐α and not‐β variants balance immune stimulation and prevent T cell exhaustion, offering a novel, fine‐tuned approach for ...
Jiaqi Sun +23 more
wiley +1 more source
Brain and Behavior, Volume 12, Issue 12, December 2022., 2022 Abstract Background There are few studies about the relationship between dietary patterns and aggression. The aim of this study was to assess the relationship between the main dietary patterns and aggression scores among adolescent girls in Iran. Methods This cross‐sectional study was conducted on 670 adolescent girls.
Mahsa Malekahmadi +8 more
wiley +1 more source
The British journal of psychiatry : the journal of mental science, 2014 BACKGROUND Pill-taking, expectations and therapeutic alliance may account for much of the benefit of medication and placebo treatment for major depressive disorder (MDD). Aims To examine the effects of medication, placebo and supportive care on treatment
A. Leuchter +3 more
semanticscholar +1 more source
RAB3B Dictates mTORC1/S6 Signaling in Chordoma and Predicts Response to mTORC1‐Targeted Therapy
Advanced Science, EarlyView.RAB3B is unveiled as a prominent oncogenic regulator in chordoma, which can block the DUSP12‐mediated dephosphorylation of p‐S6 (S235/236). The combination of RAB3B and p‐S6 indicates a good prognostic value and predicts mTORC1 inhibitors response for chordoma patients.
Jianxuan Gao +15 more
wiley +1 more source
COVID‐19 and myasthenia gravis: A review of neurological implications of the SARS‐COV‐2
Brain and Behavior, Volume 12, Issue 12, December 2022., 2022 Abstract Introduction This review highlights the potential mechanisms of neuromuscular manifestation of COVID‐19, especially myasthenia gravis (MG). Methods An extensive literature search was conducted by two independent investigators using PubMed/MEDLINE and Google Scholar from its inception to December 2020. Results Exacerbations of clinical symptoms
Syed Muhammad Ismail Shah +10 more
wiley +1 more source