Results 71 to 80 of about 14,257 (219)

Culture of cryopreserved first trimester placental tissues to study syncytial renewal

open access: yesScientific Reports
Ex vivo studies with first trimester placental tissues are crucial for understanding human placental development, and culturing placental villi in floating conditions is vital to mimic the natural setting.
Mary Mansilla, Yao Wang, Guiying Nie
doaj   +1 more source

Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner   +2 more
wiley   +1 more source

PFAS exposure during pregnancy: Implications for placental health and functioning

open access: yesEnvironment International
Background: Animal studies have linked prenatal poly- and perfluoroalkyl substances (PFAS) exposures with impaired placental structure and function. In humans, only few studies have investigated such associations.
Sadia Khan   +15 more
doaj   +1 more source

Narrative Review on Therapies That Influence Inflammatory Responses During Extremely Premature Perinatal Respiratory Transition

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aims and Methods Advances in neonatal care have extended borderline survival to 22–24 post‐conceptional weeks. Present review discusses approaches for prolonging short pregnancies and prevention of serious morbidities in extremely premature infants born before 28 weeks of pregnancy.
Mikko Hallman
wiley   +1 more source

Quantitative proteomic (iTRAQ) analysis of 1st trimester maternal plasma samples in pregnancies at risk for preeclampsia [PDF]

open access: yes, 2012
A current major obstacle is that no reliable screening markers exist to detect pregnancies at risk for preeclampsia. Quantitative proteomic analysis employing isobaric labelling (iTRAQ) has been suggested to be suitable for the detection of potential ...
Hoesli, I.   +5 more
core   +1 more source

Chorionic Villi with Placental Hypoplasia

open access: yesAnnals of Circulation
The structure and proliferation of endothelial and muscle cells of the chorionic veins of the underdeveloped placenta were studied. Histological, histochemical, and morphometric studies of the fetal membrane of the placenta of 36 placentas of 280-300 g at 39-40 weeks of pregnancy were carried out in comparison with 15 placentas of 450-500 g.
AN Gansburgsky, AV Yaltsev
openaire   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

open access: yesThe FEBS Journal, EarlyView.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo   +4 more
wiley   +1 more source

Gestational related morphological abnormalities in placental villous trophoblast turnover in compromised pregnancies

open access: yes, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Human placental villi are covered by a layer of trophoblast epithelia in direct contact with maternal blood, which exist in a constant steady-state of ...
Widdows, Kate Louise
core  

Role of matrix metalloproteinases 2 and 9 in ex vivo Trypanosoma cruzi infection of human placental chorionic villi [PDF]

open access: yes, 2012
Background: Chagas' disease is caused by the haemophlagelated protozoan Trypanosoma cruzi (T. cruzi). During congenital transmission the parasite breaks down the placental barrier.
Cabrera, G.   +8 more
core   +1 more source

High‐elevation adaptation and gestational hypoxia jointly shape vascular development in a rodent placenta

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We investigated how environmental hypoxia and genetic adaptation to high altitudes jointly impact the development of the placental exchange surface in ways that might protect fetal growth potential. We used wild‐derived, lab‐born North American deer mice (Peromyscus maniculatus) from low‐elevation and high‐elevation environments (
Kathryn Wilsterman   +6 more
wiley   +1 more source

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