Results 81 to 90 of about 96,077 (207)

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Mitochondria Respiration in the Placental Villi Tissue of Obese and Normal-Weight Women

, 2023
BACKGROUND: Maternal obesity (MO) is a risk factor for short and long-term poor outcomes, for both the mother and the offspring. Placental oxidative stress is typical in MO, and mitochondria (mt) dysfunction has been shown in placental trophoblasts.
Giovarelli M, Anelli GM, Coco C, Mando' C, Novielli C, Serati A, Cetin I   +6 more
core   +1 more source

Virus‐specific alterations in placental structure and transporter expression following maternal arbovirus infection

The Journal of Physiology, EarlyView.
Abstract figure legend Arboviruses induce virus‐specific alterations in placental structure and functional markers. Chikungunya virus (CHIKV) exposure was associated with reduced syncytiotrophoblast and syncytial knot areas, increased cytotrophoblast proliferation (Ki‐67) and thyroid transporter (MCT8) expression, reduced protective (P‐gp and BCRP ...
Cherley B. V. Andrade, Enrrico Bloise, Natália L. Silva, Jair R. S. Braga, Sharton V. A. Coelho, Veronica M. O. Nascimento, Guinever E. Imperio, Camila O. S. Nunes, Antônio J. L. A. Cunha, Marcelo A. Pascoal‐Xavier, Luciana B. Arruda, Arnaldo Prata‐Barbosa, Kristin L. Connor, Tania M. Ortiga‐Carvalho   +13 more
wiley   +1 more source

Uterus‐preserving surgery for placenta accreta spectrum: An expert, illustrated review of techniques and its outcomes

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 10, Page 1932-1949, October 2026.
Uterus‐preserving strategies for PAS include myometrial resection and leaving placenta in situ, differing in surgical principles, complications, and follow‐up. Myometrial resection offers definitive treatment with lower rates of delayed morbidity, while leaving the placenta in situ minimizes surgical risk but is associated with prolonged follow‐up ...
Pedro Viana Pinto, Albaro José Nieto‐Calvache, Rafael José Vieira, Abdalla Mousa, Hooman Soleymani majd, Rozi Aditya Aryananda, José Miguel Palacios‐Jaraquemada   +6 more
wiley   +1 more source

Human type 2 17beta-hydroxysteroid dehydrogenase mRNA and protein distribution in placental villi at mid and term pregnancy

Reproductive Biology and Endocrinology, 2007
Background During human pregnancy, the placental villi produces high amounts of estradiol. This steroid is secreted by the syncytium, which is directly in contact with maternal blood.
Plante Julie, Simard Marc, Drolet Renée, Laberge Philippe, Tremblay Yves   +4 more
doaj   +1 more source

An Integrated Proteomics and Genomics Approach to Identify Essential Protein Kinases During Human Trophoblast Development

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Integrated quantitative proteomic, phosphoproteomic, and transcriptomic analyses of human trophoblast stem cells identify stage‐specific kinase signaling networks that regulate trophoblast self‐renewal and differentiation into syncytiotrophoblasts and extravillous trophoblasts.
Rajnish Kumar, Purbasa Dasgupta, Soma Ray, Soumen Paul   +3 more
wiley   +1 more source

Histological Appearance of Placental Solomonization in the Treatment of Twin–Twin Transfusion Syndrome

American Journal of Perinatology Reports, 2016
Background Placental laser equatorialization or “solomonization” during treatment for twin–twin transfusion syndrome (TTTS) is associated with improved pregnancy outcomes.
Stephen P. Emery, Lananh Nguyen, W. Tony Parks   +2 more
doaj   +1 more source

Global Recommendations for the Use of Diagnostic Genomic Sequencing in the Prenatal Setting on Behalf of the ESHG and ISPD

Prenatal Diagnosis, EarlyView.
Zandra C. Deans, Lina Basel Salmon, Kwong Wai Choy, Guido de Wert, Zirui Dong, Lilian Downie, Francesca Romana Grati, Sabine Hentze, Paula Jorge, Brynn Levy, Luca Lovrecic, Dora Mayen, Álvaro Mendes, Michael Morris, Ashley Pritchard, Raquel Gouveia Silva, Tina‐Marié Wessels, Francesca Forzano, Natalie J. Chandler   +18 more
wiley   +1 more source

Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes

Advanced Science, Volume 13, Issue 50, 7 September 2026.
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami, Masanori Ono, Yasunari Mizumoto, Tatsuhito Kanda, Takashi Iizuka, Takiko Daikoku, Shin‐ichi Horike, Akira Hattori, Akihito Horie, Sachiko Minamiguchi, Tomoko Fujiwara, Kazuyoshi Hosomichi, Atsushi Tajima, Hirokazu Usui, Kaoru Abiko, Hiroshi Fujiwara   +15 more
wiley   +1 more source

Zika Virus Affects the Placental Villi

, 2016
The pathogenesis of Zika virus infection is not well known and the effects on the structure of the placental villi require to be investigated. Is our proposal to describe the histopathological changes that occur in the placental villi provoked by Zika ...
Olivar C Castejon
core