Results 81 to 90 of about 14,257 (219)

Human placental exposure to pollutant nanoparticles: uptake, translocation and functional impact

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to pollutant nanoparticles has been increasingly investigated due to concerns about their potential effects on placental function and pregnancy outcomes. Maternal inhalation of pollutant nanoparticles can result in a pro‐inflammatory response; particles can also translocate across the alveolus epithelial barrier
Katherine L. Bethell, Andrew C. Povey, Edward D. Johnstone, Peter T. Ruane   +3 more
wiley   +1 more source

Zika Virus Affects the Placental Villi

, 2016
The pathogenesis of Zika virus infection is not well known and the effects on the structure of the placental villi require to be investigated. Is our proposal to describe the histopathological changes that occur in the placental villi provoked by Zika ...
Olivar C Castejon
core  

Physiological and anatomical determinants of placental drug transfer

The Journal of Physiology, EarlyView.
Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis, Anandita Umapathy, Jane K. Cleal, Bram G. Sengers   +3 more
wiley   +1 more source

A primary cell‐based fluidic co‐culture model to investigate drug transport across the human placenta

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of a flow‐driven in vitro model of the human placental barrier designed to study transport processes during pregnancy. The model recreates key features of the maternal–fetal interface, enabling the investigation of how nutrients and therapeutic compounds cross the placental barrier under physiologically ...
Barbara Fuenzalida, Nadja Koechli, Edgar Ontsouka, Chennakesava Cuddapah, Martin Mueller, Bram Sengers, Frantisek Staud, Christiane Albrecht   +7 more
wiley   +1 more source

The role of soluble FMS-like tyrosine kinase (sFLT1) and FAS associated proteins in pregnancies complicated by preeclampsia and intrauterine growth restriction (IUGR).

, 2005
PhDCurrent thinking suggests that preeclampsia is associated with activation of the maternal vascular endothelium in response to factors released from the placenta due to placental hypoxia.
Fayyad, Abdalla Mustafa
core  

Mesenchymal stem cells in human placental chorionic villi reside in a vascular Niche [PDF]

, 2010
he chorionic villi of human term placentae are a rich source of mesenchymal stem cells (PMSCs). The stem cell ‘‘niche’’ within the chorionic villi regulates how PMSCs participate in placental tissue gener-ation, maintenance and repair, but the anatomic ...
Erwich, J., Gude, N. M., Erwich, J.J., Gude, N.M., Gronthos, S., Erwich, J. J. H. M., Brennecke, S., Erwich, J. J. H. M.; id_orcid, Castrechini, N., Murthi, P., Gude, N., Brennecke, S.P., Brennecke, S. R., Kalionis, B., Zannettino, A., Castrechini, N.M., Castrechini, N. M.   +16 more
core   +1 more source

Association between birth weight and percentage of placental cells with chromosomal abnormalities after long-term cultured villi for type 2 confined placental mosaicisms (CPM2) and type 3 confined placental mosaicisms (CPM3) (Pearson's correlation coefficient = -0.61, p<0.001).

, 2018
Association between birth weight and percentage of placental cells with chromosomal abnormalities after long-term cultured villi for type 2 confined placental mosaicisms (CPM2) and type 3 confined placental mosaicisms (CPM3) (Pearson's correlation ...
Robert Saura (289468), Jacques Horovitz (289464), Damien Goutte-Gattat (5095484), Jérôme Toutain (289447)   +3 more
core   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Placental crises: disruptive selection and maternal under‐investment as the foundations of mammalian placental evolution and dysfunction

Biological Reviews, Volume 101, Issue 4, Page 1627-1640, August 2026.
ABSTRACT Among the vertebrates, mammals are notable for the dominance of live birth and placental nutrition. The structural diversity of the mammalian placenta is remarkable, despite sharing a single common ancestor and conserved physiological functions.
Davis Laundon, Neil J. Gostling, Ian G. Reddin, Bram G. Sengers, Pascale Chavatte‐Palmer, Rohan M. Lewis   +5 more
wiley   +1 more source

Histological Appearance of Placental Solomonization in the Treatment of Twin–Twin Transfusion Syndrome

American Journal of Perinatology Reports, 2016
Background Placental laser equatorialization or “solomonization” during treatment for twin–twin transfusion syndrome (TTTS) is associated with improved pregnancy outcomes.
Stephen P. Emery, Lananh Nguyen, W. Tony Parks   +2 more
doaj   +1 more source