Results 101 to 110 of about 150,481 (338)

Par3 is essential for the establishment of planar cell polarity of inner ear hair cells

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Planar cell polarity (PCP) signaling coordinates cell polarization along an axis orthogonal to its apical–basal axis and is essential for both tissue development and function.
André Landin Malt, Zachary Dailey, Julia Holbrook-rasmussen, Yuqiong Zheng, Arielle Hogan, Q. Du, Xiaowei Lu   +6 more
semanticscholar   +1 more source

Retracing the path of planar cell polarity [PDF]

BMC Evolutionary Biology, 2016
The Planar Cell Polarity pathway (PCP) has been described as the main feature involved in patterning cell orientation in bilaterian tissues. Recently, a similar phenomenon was revealed in cnidarians, in which the inhibition of this pathway results in the absence of cilia orientation in larvae, consequently proving the functional conservation of PCP ...
Schenkelaars, Quentin, Fierro-Constain, Laura, Renard, Emmanuelle, Borchiellini, Carole   +3 more
openaire   +4 more sources

Packaging of Macroscopic Material Payloads: Needs, Challenges, Concepts, and Future Directions

Advanced Engineering Materials, EarlyView.
This review introduces a unified framework that decomposes any macroscopic packaging system into the payload, packaging material, and packaging strategy and combines them into a conceptual packaging equation: packaging strategy = payload + packaging material.
Venkata S. R. Jampani, Manos Anyfantakis
wiley   +1 more source

Tissue shear as a cue for aligning planar polarity in the developing Drosophila wing

Nature Communications
Planar polarity establishment in epithelia requires interpretation of directional tissue-level information at cellular and molecular levels. Mechanical forces exerted during tissue morphogenesis are emerging as crucial tissue-level directional cues, yet ...
Su Ee Tan, David Strutt
doaj   +1 more source

Characterisation of cell-scale signalling by the core planar polarity pathway during Drosophila wing development

eLife
In developing epithelia, cells become planar polarised through asymmetric localisation of the core planar polarity proteins to opposite cell membranes, where they form stable intercellular complexes.
Alexandre Carayon, Helen Strutt, David Strutt   +2 more
doaj   +1 more source

Requirement for Dlgh-1 in planar cell polarity and skeletogenesis during vertebrate development. [PDF]

PLoS ONE, 2013
The development of specialized organs is tightly linked to the regulation of cell growth, orientation, migration and adhesion during embryogenesis. In addition, the directed movements of cells and their orientation within the plane of a tissue, termed ...
Charlene Rivera, Sara J S Simonson, Idella F Yamben, Shalini Shatadal, Minh M Nguyen, Maryline Beurg, Paul F Lambert, Anne E Griep   +7 more
doaj   +1 more source

Direct Metal Deposition of Graphene–Ti28Nb35.4Zr Matrix Composites With Enhanced Mechanical, Corrosion, and Biocompatibility Properties for Bone Implants

Advanced Engineering Materials, EarlyView.
Graphene nanoplatelet (0.1 wt.%) reinforcement significantly enhances the performance of β Ti‐28Nb‐35.4Zr alloy. Grain refinement, reduced water contact angle, and improved surface characteristics promote osteoblast adhesion and complete surface coverage after 7 days.
Khurram Munir, Jixing Lin, Yuncang Li, Li Zhu, Paul F. A. Wright, Cuie Wen   +5 more
wiley   +1 more source

PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling

Cell Reports, 2019
SUMMARY Wnt signaling pathways direct key physiological decisions in development. Here, we establish a role for a pleckstrin homology domain-containing protein, PLEKHA4, as a modulator of signaling strength in Wnt receiving cells.
A. Shah, Alex G. Batrouni, Dongsung Kim, Amith Punyala, Wendy Cao, Chun Han, M. Goldberg, M. Smolka, Jeremy M. Baskin   +8 more
semanticscholar   +1 more source

Exploring Dipolar Dynamics and Ionic Transport in Metal‐Organic Frameworks: Experimental and Theoretical Insights

Advanced Functional Materials, EarlyView.
In this study, the interplay of dipolar dynamics and ionic charge transport in MOF compounds is investigated. Synthesizing the novel structure CFA‐25 with integrated freely rotating dipolar groups, local and macroscopic effects, including interactions with Cs cations are explored.
Ralph Freund, Arthur Schulz, Peter Lunkenheimer, Maryana Kraft, Thomas Bergler, Harald Oberhofer, Dirk Volkmer   +6 more
wiley   +1 more source

Apical-Basal Polarity Signaling Components, Lgl1 and aPKCs, Control Glutamatergic Synapse Number and Function. [PDF]

, 2019
Normal synapse formation is fundamental to brain function. We show here that an apical-basal polarity (A-BP) protein, Lgl1, is present in the postsynaptic density and negatively regulates glutamatergic synapse numbers by antagonizing the atypical protein
Cheng, Hongqiang, Ghosh, Sourav, Hejran, Helen, Klezovitch, Olga, Lee, Su-Yee, Mao, Ye, Mu, Yongxin, Qin, Huaping, Scott, John, Thakar, Sonal, Vasioukhin, Valeri, Yu, Ting, Zou, Yimin   +12 more
core   +1 more source